Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness

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Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness is …
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scholarly articleQ13442814

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P356DOI10.1002/JBMR.463
P932PMC publication ID3183324
P698PubMed publication ID21706518
P5875ResearchGate publication ID51251086

P50authorBruce W. HollisQ110282309
P2093author name stringCarol L Wagner
Thomas C Hulsey
Myla Ebeling
Donna Johnson
P2860cites workEvaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice GuidelineQ22306207
Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brainQ24320314
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial responseQ28298985
Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin DQ28304322
Influence of the vitamin D-binding protein on the serum concentration of 1,25-dihydroxyvitamin D3. Significance of the free 1,25-dihydroxyvitamin D3 concentrationQ28367593
Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic ratsQ28568682
Effect of vitamin D replacement on musculoskeletal parameters in school children: a randomized controlled trialQ33226868
Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responsesQ33463449
Analyzing adherence to prenatal supplement: does pill count measure up?Q33651865
Lactation and bone turnover: a conundrum of marked bone loss in the setting of coupled bone turnoverQ33786830
Vitamin D and the immune system: new perspectives on an old themeQ33888744
Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactinQ33993870
Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitisQ34026830
Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferolQ34166759
A diet history questionnaire ranks nutrient intakes in middle-aged and older men and women similarly to multiple food recordsQ34362580
Williams syndrome and related disordersQ34433419
Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trialQ34511555
Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal painQ34543762
Maternal vitamin D deficiency increases the risk of preeclampsiaQ34579840
Vitamin D deficiency and risk of cardiovascular diseaseQ34586829
Association between vitamin D deficiency and primary cesarean sectionQ34602371
Membrane mediated signaling mechanisms are used differentially by metabolites of vitamin D(3) in musculoskeletal cellsQ34605426
Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver diseaseQ34621374
Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunityQ34739582
Craniotabes in normal newborns: the earliest sign of subclinical vitamin D deficiencyQ34749457
Intrauterine vitamin D nutrition and postnatal growth in Asian infantsQ34784381
25-Hydroxylation of vitamin D3: relation to circulating vitamin D3 under various input conditionsQ34785596
Calcitonin and bone formation: a knockout full of surprisesQ34818417
Cord blood vitamin D status impacts innate immune responsesQ35001919
Epigenetic reduction in invariant NKT cells following in utero vitamin D deficiency in miceQ35079347
Maternal vitamin D and fetal growth in early-onset severe preeclampsiaQ35106064
Presentation of vitamin D deficiencyQ35280485
Maternal compared with infant vitamin D supplementationQ35603461
Assessment of dietary vitamin D requirements during pregnancy and lactationQ35758404
Vitamin D insufficiency in congestive heart failure: why and what to do about it?Q36526889
Elevated 1,25-dihydroxyvitamin D plasma levels in normal human pregnancy and lactationQ37036056
Significant vitamin D deficiency in youth with type 1 diabetes mellitusQ37083977
Vitamin d-directed rheostatic regulation of monocyte antibacterial responsesQ37195938
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interfaceQ37200849
The mechanisms of vitamin D toxicityQ37790613
A physiological role for calcitonin: protection of the maternal skeletonQ39568647
Nutritional Influences During PregnancyQ39617168
Possible Injury to the Cardiovascular System from Vitamin DQ40040669
Endocrine Regulation of Calcium Homeostasis During PregnancyQ40165839
Vitamin D3 and brain developmentQ40652918
Rickets in an infant with Williams syndromeQ41744051
Elevated 1,25-dihydroxyvitamin D and normocalcaemia in presumed familial Williams syndromeQ41932633
Calcitonin, a regulator of the 25-hydroxyvitamin D3 1alpha-hydroxylase geneQ43144652
The relationship of 1,25-dihydroxyvitamin D and radial bone massQ43472595
Vitamin D supplementation for non-Western pregnant women: the British experienceQ43806314
Prevention of rickets and vitamin D deficiency in infants, children, and adolescentsQ43826048
Williams syndrome: clinical, cytogenetical, neurophysiological and neuroanatomic studyQ44113543
Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D.Q44273267
Vitamin D supplements enhance weight gain and nutritional status in pregnant Asians.Q44379816
1,25-dihydroxyvitamin D3 induces nerve growth factor, promotes neurite outgrowth and inhibits mitosis in embryonic rat hippocampal neurons.Q44448707
Comparison of two dietary questionnaires validated against multiple dietary records collected during a 1-year periodQ44752024
Vitamin D as a defensin.Q46009356
Vitamin D deficiency in pregnant women from a non-European ethnic minority population--an interventional studyQ46485201
Maternal vitamin D depletion alters neurogenesis in the developing rat brainQ48184447
Nutrition and the developing brain: nutrient priorities and measurementQ48281043
Glucose intolerance and impairment of insulin secretion in relation to vitamin D deficiency in east London Asians.Q51025297
Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D.Q51537354
Correlation between vitamin D3 deficiency and insulin resistance in pregnancy.Q51911247
Immunonephelometric assay of vitamin D-binding protein.Q52414593
An evaluation of a food frequency questionnaire for assessing dietary intake of specific carotenoids and vitamin E among low-income black women.Q53855790
Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth.Q55113417
Vitamin-D requirements in pregnancy.Q55334240
A case of idiopathic hypercalcemia (hypersensitivity to vitamin D 3Q67867038
Vitamin D supplementation during pregnancy: effect on neonatal calcium homeostasisQ68802263
Vitamin D supplementation in pregnancy: a controlled trial of two methodsQ69612619
Validation of a retrospective questionnaire assessing diet 10-15 years agoQ69646359
Elevated plasma 1,25-dihydroxyvitamin D concentrations in infants with hypercalcemia and an elfin faciesQ69801626
Determination of vitamin D status by radioimmunoassay with an 125I-labeled tracerQ70598693
Effects of vitamin D supplementation in pregnancyQ70795218
High concentrations of vitamin D2 in human milk associated with pharmacologic doses of vitamin D2Q71010737
Quantification of circulating 1,25-dihydroxyvitamin D by radioimmunoassay with 125I-labeled tracerQ71011309
Vitamin D deficiency in homebound elderly personsQ71516268
Abnormal regulation of circulating 25-hydroxyvitamin D in the Williams syndromeQ72104392
Vitamin D as a cause of the supravalvular aortic stenosis syndromeQ72218378
Evaluation of the Total Fetomaternal Vitamin D Relationships at Term: Evidence for Racial Differences*Q72393749
Determinants of plasma vitamin E in healthy malesQ72555830
Familial occurrence of idiopathic infantile hypercalcemiaQ73030892
Congenital rickets due to maternal vitamin D deficiency in a sunny island of GreeceQ73340991
Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect levelQ73396246
Preeclampsia is associated with low circulating levels of insulin-like growth factor I and 1,25-dihydroxyvitamin D in maternal and umbilical cord compartmentsQ73866967
Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damageQ74243201
ASSOCIATION BETWEEN AORTIC STENOSIS AND FACIES OF SEVERE INFANTILE HYPERCALCAEMIAQ76522979
Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infantQ81111248
Vitamin D deficiency in early infancyQ81320615
Normal serum vitamin D levelsQ81358169
Vitamin D deficiency and supplementation during pregnancyQ81930448
Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthmaQ83039767
P433issue10
P921main subjectvitamin DQ175621
P304page(s)2341-2357
P577publication date2011-10-01
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleVitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness
P478volume26

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Q45782337The role of hypovitaminosis D in pregnancy-related venous thromboembolism
Q30416484The role of vitamin D in pregnancy and lactation: emerging concepts
Q30234422The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention
Q53234382Time-course analysis of 3-epi-25-hydroxyvitamin D3 shows markedly elevated levels in early life, particularly from vitamin D supplementation in preterm infants.
Q93031548Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth
Q48158641Transient neonatal hypercalcaemia secondary to excess maternal vitamin D intake: too much of a good thing.
Q35917808Treatment of vitamin D deficiency is an effective method in the elimination of asymptomatic bacterial vaginosis: A placebo-controlled randomized clinical trial.
Q55515171Trimester-Specific Dietary Intakes in a Sample of French-Canadian Pregnant Women in Comparison with National Nutritional Guidelines.
Q34473938Typical prenatal vitamin D supplement intake does not prevent decrease of plasma 25-hydroxyvitamin D at birth.
Q38817149Ultraviolet radiation and effects on humans: the paradigm of maternal vitamin D production during pregnancy.
Q97071898Update of the tolerable upper intake level for vitamin D for infants
Q27690927Update on vitamin D: More than just a nutrient
Q52658055Use of Placebo in Supplementation Studies-Vitamin D Research Illustrates an Ethical Quandary.
Q44632031Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program
Q26852292Vitamin D - roles in women's reproductive health?
Q91760878Vitamin D Concentration during Early Pregnancy and Adverse Outcomes among HIV-Negative Women in Dar-es-Salaam, Tanzania: A Case-Control Study
Q41178577Vitamin D Deficiency and Gallbladder Stasis
Q57611498Vitamin D Deficiency in Infants
Q47992286Vitamin D Deficiency in Pregnant Women and Their Infants
Q37339123Vitamin D Deficiency in Pregnant Women and Their Neonates
Q35891922Vitamin D Deficiency: This clandestine endemic disease is veiled no more.
Q42407595Vitamin D Metabolism Varies among Women in Different Reproductive States Consuming the Same Intakes of Vitamin D and Related Nutrients
Q35389974Vitamin D Status Affects Serum Metabolomic Profiles in Pregnant Adolescents
Q91955074Vitamin D Status Increases During Pregnancy and in Response to Vitamin D Supplementation in Rural Gambian Women
Q57928309Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth
Q38953734Vitamin D administration during pregnancy as prevention for pregnancy, neonatal and postnatal complications.
Q26801481Vitamin D and Inflammatory Cytokines in Healthy and Preeclamptic Pregnancies
Q27012365Vitamin D and Reproduction: From Gametes to Childhood
Q37977201Vitamin D and adverse pregnancy outcomes: beyond bone health and growth
Q39144032Vitamin D and autism, what's new?
Q37302666Vitamin D and bronchopulmonary dysplasia in preterm infants
Q57934019Vitamin D and fetal-neonatal calcium homeostasis: findings from a randomized controlled trial of high-dose antenatal vitamin D supplementation
Q38936663Vitamin D and its impact on maternal-fetal outcomes in pregnancy: A critical review.
Q22305602Vitamin D and its role during pregnancy in attaining optimal health of mother and fetus
Q38110772Vitamin D and maternal and child health: overview and implications for dietary requirements
Q38058150Vitamin D and neonatal immune function.
Q38012669Vitamin D and pregnancy: skeletal effects, nonskeletal effects, and birth outcomes
Q38123750Vitamin D and skeletal growth and development
Q91318939Vitamin D binding protein polymorphisms significantly impact vitamin D status in children
Q92784201Vitamin D deficiency 2.0: an update on the current status worldwide
Q35898169Vitamin D deficiency and supplementation in pregnancy in a multiethnic population-based cohort
Q37697181Vitamin D deficiency in cord plasma from multiethnic subjects living in the tropics
Q33819545Vitamin D deficiency in critically ill children
Q35514703Vitamin D deficiency in early pregnancy
Q37349712Vitamin D during pregnancy and maternal, neonatal and infant health outcomes: a systematic review and meta-analysis
Q38556295Vitamin D during pregnancy: why observational studies suggest deficiency and interventional studies show no improvement in clinical outcomes? A narrative review.
Q36382400Vitamin D improves the angiogenic properties of endothelial progenitor cells.
Q37055829Vitamin D in Children's Health
Q38400838Vitamin D in childhood and adolescence: an expert position statement
Q26849410Vitamin D in early childhood and the effect on immunity to Mycobacterium tuberculosis
Q55074474Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians.
Q37005435Vitamin D in pregnancy: current concepts
Q38058151Vitamin D in the maternal-fetal-neonatal interface: clinical implications and requirements for supplementation
Q35795116Vitamin D insufficiency is prevalent and vitamin D is inversely associated with parathyroid hormone and calcitriol in pregnant adolescents
Q40216793Vitamin D levels during pregnancy and associations with birth weight and body composition of the newborn: a longitudinal multiethnic population-based study
Q55434226Vitamin D levels in an Australian and New Zealand cohort and the association with pregnancy outcome.
Q36984964Vitamin D nutrition in pregnancy: current opinion
Q38839823Vitamin D replacement in children, adolescents and pregnant women in the Middle East and North Africa: A systematic review and meta-analysis of randomized controlled trials
Q37920578Vitamin D requirements and supplementation during pregnancy
Q40031937Vitamin D status among 4-month-old infants in New England: a prospective cohort study
Q35147031Vitamin D status among preterm and full-term infants at birth
Q36537925Vitamin D status and recurrent preterm birth: a nested case-control study in high-risk women
Q64987332Vitamin D status during pregnancy: The importance of getting it right.
Q38381692Vitamin D status during pregnancy: time for a more unified approach beyond borders?
Q43580787Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size
Q37256236Vitamin D status in early pregnancy and risk of preeclampsia
Q64281526Vitamin D status in pregnant women visiting a tertiary care center of North Eastern India
Q38873719Vitamin D status in wild toque macaques (Macaca sinica) in Sri Lanka
Q43938542Vitamin D status indicators in indigenous populations in East Africa
Q37709498Vitamin D study in pregnant women and their babies
Q26766130Vitamin D supplementation during pregnancy: Updated meta-analysis on maternal outcomes
Q24186477Vitamin D supplementation for women during pregnancy
Q24203647Vitamin D supplementation for women during pregnancy
Q94348236Vitamin D supplementation in pregnancy
Q47391798Vitamin D testing in pregnancy: Does one size fit all?
Q53763724Vitamin D treatment in Somali women living in Sweden - Two randomized, placebo-controlled studies.
Q55400588Vitamin D, Gestational Diabetes, and Measures of Glucose Metabolism in a Population-Based Multiethnic Cohort.
Q92026784Vitamin D, and Maternal and Child Health
Q84516535Vitamin D3 supplementation (4000 IU/d for 1 y) eliminates differences in circulating 25-hydroxyvitamin D between African American and white men
Q36069763Vitamin D3 supplementation at 4000 international units per day for one year results in a decrease of positive cores at repeat biopsy in subjects with low-risk prostate cancer under active surveillance
Q37029038Vitamin D: beyond bone
Q38079134Vitamin D: effects on childhood health and disease.
Q27008545Vitamin d status in central europe
Q40279324Vitamin-D Deficiency Is Associated with Gallbladder Stasis Among Pregnant Women
Q58695706Women who suffer from schizophrenia: Critical issues

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