Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia

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Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3324/HAEMATOL.2011.040535
P932PMC publication ID3186305
P698PubMed publication ID21750091
P5875ResearchGate publication ID51486581

P50authorFelipe ProsperQ37835050
Xabier AgirreQ40931651
Eva LumbrerasQ53101825
Miguel A SanzQ54544774
Miren MaicasQ57157699
P2093author name stringSalut Brunet
María D Odero
María J Calasanz
Nerea Marcotegui
Claudia Carranza
Idoya Lahortiga
Ana Valencia
José Cervera
Carmen Vicente
Jorge Sierra
Jesús M Hernández-Rivas
Iria Vázquez
Maria Gomez-Benito
María T Gómez-Casares
Oskar Marin-Béjar
P2860cites workIntergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain familyQ24314719
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignanciesQ27824769
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patientsQ28209409
Expression and prognostic significance of different mRNA 5'-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission durationQ28263954
EVI1 and hematopoietic disorders: history and perspectivesQ28284034
Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemiasQ28301353
The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functionsQ28302636
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genomeQ29616819
Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.Q33805966
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous diseaseQ34094502
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.Q34508425
Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumorsQ36780634
Leukemogenesis of the EVI1/MEL1 gene familyQ36812700
Acute myeloid leukemia: the challenge of capturing disease varietyQ37346654
Genome‐wide DNA methylation profilingQ37788000
EVI1 induces myelodysplastic syndrome in miceQ39951095
BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemiaQ39974408
Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5'-ends.Q40398239
AML1 mutations induced MDS and MDS/AML in a mouse BMT modelQ42818187
EVI-1 oncogene expression predicts survival in chronic-phase CML patients resistant to imatinib treated with second-generation tyrosine kinase inhibitorsQ42882348
Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemiaQ44073895
Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements.Q44893063
EVI1 is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangementsQ49097152
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.Q51956004
Prognostically useful gene-expression profiles in acute myeloid leukemia.Q51999490
Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells.Q53361854
High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.Q54546717
Internal tandem duplication of the flt3 gene found in acute myeloid leukemiaQ71841108
Mapping of leukaemia-associated breakpoints in chromosome band 3q21 using a newly established PAC contigQ74260823
Diagnosis and prognosis in acute myeloid leukemia--the art of distinctionQ81197668
Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cellsQ83058254
High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalitiesQ83822325
Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemiaQ84596053
P433issue10
P921main subjectacute myeloid leukemiaQ264118
P304page(s)1448-1456
P577publication date2011-07-12
P1433published inHaematologicaQ5638209
P1476titleDown-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia
P478volume96

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cites work (P2860)
Q38882990A murine model of acute myeloid leukemia with Evi1 overexpression and autocrine stimulation by an intracellular form of GM-CSF in DA-3 cells.
Q35565945A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells
Q42361215DNA Methylation Events as Markers for Diagnosis and Management of Acute Myeloid Leukemia and Myelodysplastic Syndrome.
Q34606698EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells
Q38314944EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis
Q42979885EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia.
Q38299701EVI1 promotes tumor growth via transcriptional repression of MS4A3.
Q55714578Ecotropic viral integration site 1 regulates the progression of acute myeloid leukemia via MS4A3-mediated TGFβ/EMT signaling pathway.
Q37965026Epigenetic regulation of miRNA genes in acute leukemia.
Q35726371Epigenetics in diagnosis, prognostic assessment and treatment of cancer: an update
Q39332914Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.
Q34516815High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia
Q33412515Myeloid neoplasm with t(3;8)(q26;q24): report of six cases and review of the literature
Q38166375Noncoding RNAs in Acute Myeloid Leukemia: From Key Regulators to Clinical Players
Q34849602Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.
Q39305389Selection for Evi1 activation in myelomonocytic leukemia induced by hyperactive signaling through wild-type NRas
Q89651160The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development
Q41930387The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid
Q52680326The role of zinc and its compounds in leukemia.
Q84782684Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases
Q60306602miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1

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