tofacitinib

chemical compound

Wikidata entity: Q3530324

C₁₆H₂₀N₆O (P274)


Wikimedia Commons category is Tofacitinib

Quantities

P4250defined daily dose10
P2067mass312.17

P3780 active ingredient in ... Q47522319 (Xeljanz) Xeljanz
P233 canonical SMILES String CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N ???
P373 Commons category String Tofacitinib ???
P366 has use ... Q12140 (medication) medication
P366 has use ... Q25326509 (chemical probe) chemical probe
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P2017 isomeric SMILES String C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N ???
P3493 legal status (medicine) ... Q879952 (boxed warning) boxed warning
P8026 LiverTox likelihood score ... Q83284878 (Լյարդի ախտահարման հավանականության E կատեգորիա) Լյարդի ախտահարման հավանականության E կատեգորիա
P2175 medical condition treated ... Q1477 (ulcerative colitis) ulcerative colitis
P2175 medical condition treated ... Q170990 (arthritis) arthritis
P2175 medical condition treated ... Q181391 (hair loss) hair loss
P2175 medical condition treated ... Q1274464 (polyarthritis) polyarthritis
P2175 medical condition treated ... Q5075435 (alopecia areata) alopecia areata
P2175 medical condition treated ... Q55781316 (osteoarthritis susceptibility 1) osteoarthritis susceptibility 1
P129 physically interacts with ... Q6155969 (Janus kinase 3) Janus kinase 3
P3489 pregnancy category ... Q28123617 (US pregnancy category C) US pregnancy category C
P3364 stereoisomer of ... Q72493065 ((3S,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile) (3S,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile
P3364 stereoisomer of ... Q72493069 ((3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile) (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile
P3364 stereoisomer of ... Q72493072 ((3S,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile) (3S,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile
P279 subclass of ... Q11173 (chemical compound) chemical compound
P2868 subject has role ... Q7251487 (protein kinase inhibitors) protein kinase inhibitors
P2275 World Health Organisation international non-proprietary name Monolingualtext tofacitinib ???
External Ids
P267ATC codeL04AA29
P231CAS Registry Number477600-75-2
P683ChEBI ID71200
P592ChEMBL IDCHEMBL221959
P661ChemSpider ID8102425
P715DrugBank IDDB08895
P11198DrugCentral ID4713
P8494DSSTOX compound identifierDTXCID00119762
P3117DSSTox substance IDDTXSID90197271
P232EC number689-145-4
P2566ECHA Substance Infocard ID100.215.928
P646Freebase ID/m/0gfhs9b
P595Guide to Pharmacology Ligand ID5677
P2062HSDB ID8311
P234InChIInChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
P235InChIKeyUJLAWZDWDVHWOW-YPMHNXCESA-N
P665KEGG IDD09970
P7830LiverTox IDTofacitinib
P10245MedlinePlus drug identifiera613025
P486MeSH descriptor IDC479163
P6366Microsoft Academic ID (discontinued)2778886723
P2115NDF-RT IDN0000186059
P10283OpenAlex IDC2778886723
P3636PDB ligand IDMI1
P638PDB structure ID3EYG
P638PDB structure ID3LXN
P638PDB structure ID4OTI
P638PDB structure ID3LXK
P638PDB structure ID3FUP
P11199Probes And Drugs IDPD004666
P662PubChem CID9926791
P1579Reaxys registry number11647225
P3345RxNorm CUI1357536
P2877SureChEMBL ID322753
P2892UMLS CUIC2930696
P11089UniChem compound ID540499
P652UNII87LA6FU830
P11143WikiProjectMed IDTofacitinib

Why not click here or view trends?

log id: 2391116