Proteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin resistance

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Proteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/MCP.M114.039651
P932PMC publication ID4390267
P698PubMed publication ID25616869

P50authorPer-Olof BerggrenQ5571984
Suh Pann-GhillQ28323137
P2093author name stringDaehee Hwang
Sung Ho Ryu
Yoe-Sik Bae
Jaeyoon Kim
Yonghoon Kwon
Soyeon Park
Dayea Kim
Jaewang Ghim
Jong Hyuk Yoon
Parkyong Song
Jin-Hyeok Jang
P2860cites workFeature-based prediction of non-classical and leaderless protein secretionQ28259109
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Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide.Q46513293
Déjà vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins.Q46622407
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cellsQ46748522
Comparative proteomic analysis of the insulin-induced L6 myotube secretomeQ47200207
Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment.Q47671597
Lipid metabolism in diet-induced obese rabbits is similar to that of obese humans.Q51714266
Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient miceQ60642304
Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptorsQ28512121
SignalP 4.0: discriminating signal peptides from transmembrane regionsQ29547202
Adipokines in inflammation and metabolic diseaseQ29620456
A uniform proteomics MS/MS analysis platform utilizing open XML file formatsQ30478423
The APEX Quantitative Proteomics Tool: generating protein quantitation estimates from LC-MS/MS proteomics resultsQ33391589
Generally detected proteins in comparative proteomics--a matter of cellular stress response?Q33439008
Trans-proteomic pipeline: a pipeline for proteomic analysisQ34088315
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammationQ34095174
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in miceQ34178121
Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes.Q34251073
Annexin peptide Ac2-26 suppresses TNFα-induced inflammatory responses via inhibition of Rac1-dependent NADPH oxidase in human endothelial cellsQ34700008
Muscle as an endocrine organ: focus on muscle-derived interleukin-6.Q34857249
Identification of differentially regulated secretome components during skeletal myogenesisQ34994347
Palmitic acid acutely stimulates glucose uptake via activation of Akt and ERK1/2 in skeletal muscle cells.Q35067310
Metabolic syndrome: a clinical and molecular perspectiveQ36014668
Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signalingQ36098069
Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways.Q36145284
Role of myokines in exercise and metabolismQ36755279
Discoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle.Q36842237
TRIB3 mediates glucose-induced insulin resistance via a mechanism that requires the hexosamine biosynthetic pathwayQ37333602
Endocrine and liver interaction: the role of endocrine pathways in NASH.Q37433786
Morbid obesity in pediatric diabetes mellitus: surgical options and outcomesQ37788953
Lipid parameters for measuring risk of cardiovascular diseaseQ37833906
Annexin A1: novel roles in skeletal muscle biologyQ37972834
Secretomics for skeletal muscle cells: a discovery of novel regulators?Q38025270
Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cellsQ38347835
Proteomic analysis of tumor necrosis factor-alpha (TNF-α)-induced L6 myotube secretome reveals novel TNF-α-dependent myokines in diabetic skeletal muscleQ38500248
Attenuation of plasma annexin A1 in human obesityQ39265423
Regulation of lung fibroblast activation by annexin A1.Q39317340
Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activationQ39768542
Lipid induced overexpression of NF-kappaB in skeletal muscle cells is linked to insulin resistance.Q39900993
Pituitary adenylate cyclase-activating polypeptide 27 is a functional ligand for formyl peptide receptor-like 1.Q40313159
Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signallingQ41834792
Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcriptionQ42247586
Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytesQ42828051
Edward F. Adolph distinguished lecture: muscle as an endocrine organ: IL-6 and other myokinesQ43288569
P4510describes a project that usesImageJQ1659584
P433issue4
P921main subjectsecretomeQ17042943
insulin resistanceQ1053470
P304page(s)882-892
P577publication date2015-01-23
P1433published inMolecular & Cellular ProteomicsQ6895932
P1476titleProteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin resistance
P478volume14

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cites work (P2860)
Q47979606Annexin A1 and specialized proresolving lipid mediators: promoting resolution as a therapeutic strategy in human inflammatory diseases.
Q64078784Annexin-A1: Therapeutic Potential in Microvascular Disease
Q92130001Annexins in Adipose Tissue: Novel Players in Obesity
Q55714697Annexins in Translational Research: Hidden Treasures to Be Found.
Q37724747Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines
Q112748106Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk
Q88595362Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle
Q53809093Myostatin in relation to physical activity and dysglycaemia and its effect on energy metabolism in human skeletal muscle cells.
Q57786860NOTUM Is Involved in the Progression of Colorectal Cancer
Q41694441Oleate Prevents Palmitate-Induced Atrophy via Modulation of Mitochondrial ROS Production in Skeletal Myotubes.
Q92126409Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading
Q92570255Secretomics to Discover Regulators in Diseases
Q64068253The effect of type 2 diabetes mellitus and obesity on muscle progenitor cell function
Q38951385The ever-expanding myokinome: discovery challenges and therapeutic implications

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