The nerve growth factor family of receptors

scientific article published on September 1, 1992

The nerve growth factor family of receptors is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/0166-2236(92)90047-C
P698PubMed publication ID1382329

P50authorSusan O MeakinQ55476731
P2093author name stringE. M. Shooter
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)323-331
P577publication date1992-09-01
P1433published inTrends in NeurosciencesQ3538443
P1476titleThe nerve growth factor family of receptors
P478volume15

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cites work (P2860)
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Q47846225Eradication of cerebellar granular cells alters the developmental expression of trk receptors in the rat inferior olive
Q48648964Ethanol reduces expression of the nerve growth factor receptor, but not nerve growth factor protein levels in the neonatal rat cerebellum
Q41036302Evidence for the participation of nerve growth factor and its low-affinity receptor (p75NTR) in the regulation of the myogenic program
Q73908111Expression of TrkB-like immunoreactivity in non-neural cells of rat periodontal ligament
Q46911500Expression of nerve growth factor and its receptors NTRK1 and TNFRSF1B is regulated by estrogen and progesterone in the uteri of golden hamsters
Q36822896Expression of nerve growth factor, p75, and trk in the somatosensory and motor cortices of mature rats: evidence for local trophic support circuits
Q48397328Expression of neurotrophins and neurotrophin receptors in the cerebellum of mutant weaver and lurcher mice
Q48196774Expression of p75(NTR), trkB and trkC in nonmanipulated and axotomized motoneurons of aged rats
Q37712795Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells
Q35207002Expression of trk in MAH cells lacking the p75 low-affinity nerve growth factor receptor is sufficient to permit nerve growth factor-induced differentiation to postmitotic neurons
Q46738962Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung
Q37696831Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.
Q73303512Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells
Q33889310Glial cells as targets and producers of neurotrophins
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Q38309416Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration
Q46256533Heterodimeric neurotrophins induce phosphorylation of Trk receptors and promote neuronal differentiation in PC12 cells
Q48222648High affinity neurotrophin receptors in the human pre-term newborn, infant, and adult cerebellum
Q45308842Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells.
Q36097231Human β-NGF gene transferred to cat corneal endothelial cells
Q22253946Identification of a novel testis-specific leucine-rich protein in humans and mice
Q43772811Identification of a novel truncated isoform of trkB in the kitten primary visual cortex
Q40729052Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B.
Q34060954Immunocytochemical demonstration of nerve growth factor receptor (NGF-R) in developing human fetal teeth
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Q37912174Is it possible to improve neurodevelopmental abnormalities in Down syndrome?
Q74351838Islet injury induces neurotrophin expression in pancreatic cells and reactive gliosis of peri-islet Schwann cells
Q47988662Level of p75 receptor expression in sensory ganglia is modulated by NGF level in the target tissue.
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Q41288233Neural plasticity after brain damage
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Q59081501Neuronal self-reliance
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Q60215279Neurotrophic factors
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Q40437150Neurotrophic factors: from structure-function studies to designing effective therapeutics
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Q39446326Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum.
Q22009983Organisation of the mouse and human 5T4 oncofoetal leucine-rich glycoprotein genes and expression in foetal and adult murine tissues
Q47303845Overexpression of nerve growth factor in skin increases sensory neuron size and modulates Trk receptor expression
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Q40633474Pathophysiology of glial growth factor receptors
Q48185000Pattern of trkB protein-like immunoreactivity in vivo and the in vitro effects of brain-derived neurotrophic factor (BDNF) on developing cochlear and vestibular neurons
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Q91669394Peripheral and Central Mechanisms of Persistent Orofacial Pain
Q42537637Persistence and atrophy of septal/diagonal band neurons expressing the p75 neurotrophin receptor in pilocarpine-induced chronic epilepsy in the rat.
Q28263471Phytochemicals that regulate neurodegenerative disease by targeting neurotrophins: a comprehensive review
Q41071685Plasticity following neonatal visual cortex damage in cats
Q44870034Possible role of CREB in the stimulation of oligodendrocyte precursor cell proliferation by neurotrophin-3.
Q77610837Predominant neuronal B-cell loss in L5 DRG of p75 receptor-deficient mice
Q44080727Prenatal choline supplementation increases NGF levels in the hippocampus and frontal cortex of young and adult rats
Q44239054Preovulatory rise of NGF in ovine follicular fluid: possible involvement in the control of oocyte maturation.
Q92730576Pro-Nerve Growth Factor Induces Activation of RhoA Kinase and Neuronal Cell Death
Q41314481Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors
Q30675835Prolonged exposure to elevated levels of endogenous nerve growth factor affects the morphological and neurochemical features of sympathetic neurons of postnatal and adult mice
Q49039784Prolonged recycling of internalized neurotrophins in the nerve terminal
Q28576019Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions
Q41108097Recombinant fish neurotrophin-6 is a heparin-binding glycoprotein: implications for a role in axonal guidance
Q48321289Reduced tyrosine kinase receptor C mRNA levels in the frontal cortex of patients with schizophrenia.
Q41036295Regulation of nerve growth factor and its low-affinity receptor (p75NTR) during myogenic differentiation
Q51371003Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin.
Q47774999Rescue of dorsal root sensory neurons by nerve growth factor and neurotrophin-3, but not brain-derived neurotrophic factor or neurotrophin-4, is dependent on the level of the p75 neurotrophin receptor
Q37260469Retrograde transport of neurotrophins from the eye to the brain in chick embryos: roles of the p75NTR and trkB receptors
Q35736856Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor
Q34299639Role of environmental factors on brain development and nerve growth factor expression
Q41518892Role of nerve growth factor in oxidant homeostasis: glutathione metabolism
Q33646680Safety and pharmacokinetics of escalating doses of human recombinant nerve growth factor eye drops in a double-masked, randomized clinical trial
Q48248394Selective up-regulation of P- and R-type Ca2+ channels in rat embryo motoneurons by BDNF.
Q34338664Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.
Q33793237Signaling of neuronal cell death by the p75NTR neurotrophin receptor
Q52165923Signalling organelle for retrograde axonal transport of internalized neurotrophins from the nerve terminal.
Q44227599Spatial distribution of nociceptive neuropeptide and nerve growth factor depletion in experimental diabetic peripheral nervous system
Q71874639Spatiotemporal selective effects on brain-derived neurotrophic factor andtrkB messenger RNA in rat hippocampus by electroconvulsive shock
Q71816063Specific neurotrophin binding to leucine‐rich motif peptides of TrkA and TrkB
Q73066306Structural and functional diversity in the leucine-rich repeat family of proteins
Q40374660Structural and functional properties of the TRK family of neurotrophin receptors
Q40590887Structure-function relationships in the neurotrophin family
Q42551795Systemic capsaicin in the adult rat differentially affects gene expression for neuropeptides and neurotrophin receptors in primary sensory neurons
Q41209277Tachykinins, neurotrophism and neurodegenerative diseases: a critical review on the possible role of tachykinins in the aetiology of CNS diseases
Q28591473Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
Q40839552The G-protein inhibitor, pertussis toxin, inhibits the secretion of brain-derived neurotrophic factor
Q37482481The NGF saga: from animal models of psychosocial stress to stress-related psychopathology
Q47159403The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor
Q41344531The biosynthesis of neurotrophin heterodimers by transfected mammalian cells
Q34427696The cellular and molecular basis of peripheral nerve regeneration
Q37333190The coming of age of axonal neurotrophin signaling endosomes
Q33367838The concept of uptake and retrograde transport of neurotrophic molecules during development: history and present status
Q42459509The distribution of neurotrophin receptor TrkC-like immunoreactive fibers and varicosities in the rhesus monkey brain.
Q36281327The interaction of neurotrophins with the p75NTR common neurotrophin receptor: a comprehensive molecular modeling study
Q40488050The molecular basis for T cell help in humoral immunity: CD40 and its ligand, gp39
Q38342973The p75 neurotrophin receptor enhances TrkA signalling by binding to Shc and augmenting its phosphorylation
Q42078588The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw.
Q31832151The regulation of presenilin-1 by nerve growth factor
Q42448521The regulatory role of nerve growth factor and its receptor system in fibroblast-like synovial cells
Q41168866The response of motoneurons to neurotrophins
Q28297385The role of neuroinflammation in neuropathic pain: mechanisms and therapeutic targets
Q74697359The role of neuronal growth factors in neurodegenerative disorders of the human brain
Q41079607The role of the nerve growth factor carboxyl terminus in receptor binding and conformational stability
Q40607816The role of trophic factors and autocrine/paracrine growth factors in brain metastasis
Q28139721The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation
Q38289683The sugar code in neuronal physiology
Q57526641The treatment of Alzheimer's disease
Q73470143The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor
Q34222320Threshold-free population analysis identifies larger DRG neurons to respond stronger to NGF stimulation.
Q38360562Transphosphorylation of the neurotrophin Trk receptors
Q48880171Trk receptor alterations in Alzheimer's disease.
Q34442757TrkA cross-linking mimics neuronal responses to nerve growth factor
Q43728430TrkB dimerization during development of the prefrontal cortex of the macaque
Q40425890Trophic factor response to neuronal stimuli or injury
Q41121033Trophic factors and central nervous system metastasis
Q48003346Trophic factors, synaptic plasticity, and memory
Q41921451Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro
Q40624481Tumour necrosis factor‐alpha‐ vs. growth factor deprivation‐promoted cell death: distinct converging pathways
Q36259409Two peptides derived from the nerve growth factor precursor are biologically active
Q40872205Tyrosine 785 is a major determinant of Trk--substrate interaction
Q78841845Upregulation of TrkA neurotrophin receptor expression in the thymic subcapsular, paraseptal, perivascular, and cortical epithelial cells during thymus regeneration
Q38355981p75(NGFR) and TrkA receptors collaborate to rapidly activate a p75(NGFR)-associated protein kinase.
Q71845313p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF
Q47734647trkB messenger RNA expression in normal human brain and in the substantia nigra of parkinsonian patients: an in situ hybridization study
Q24564488trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities

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