| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Adrian R Ferré-D'Amaré | |
| Katherine E Deigan | |||
| P2860 | cites work | The distributions, mechanisms, and structures of metabolite-binding riboswitches | Q21184134 |
| An mRNA structure that controls gene expression by binding FMN | Q24541465 | ||
| Structural basis of ligand binding by a c-di-GMP riboswitch | Q24602499 | ||
| Reengineering orthogonally selective riboswitches | Q24625259 | ||
| Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch | Q24629812 | ||
| Structural basis for recognition of S-adenosylhomocysteine by riboswitches | Q24630218 | ||
| Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism | Q24630273 | ||
| Crystal structure of the lysine riboswitch regulatory mRNA element | Q24646661 | ||
| An mRNA structure in bacteria that controls gene expression by binding lysine | Q24646894 | ||
| Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase | Q24655662 | ||
| Structural investigation of the GlmS ribozyme bound to Its catalytic cofactor | Q24670513 | ||
| Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B | Q27622070 | ||
| Structural mechanism for STI-571 inhibition of abelson tyrosine kinase | Q27627097 | ||
| Aminoglycoside binding displaces a divalent metal ion in a tRNA-neomycin B complex | Q27632032 | ||
| Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure | Q27643404 | ||
| Structure and mechanism of a metal-sensing regulatory RNA | Q27647828 | ||
| Requirement of Helix P2.2 and Nucleotide G1 for Positioning the Cleavage Site and Cofactor of the glmS Ribozyme | Q27647856 | ||
| Essential role of an active-site guanine in glmS ribozyme catalysis | Q27648983 | ||
| Structure of the SAM-II riboswitch bound to S-adenosylmethionine | Q27649559 | ||
| Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch | Q27650757 | ||
| Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme | Q27650804 | ||
| Structural insights into amino acid binding and gene control by a lysine riboswitch | Q27652083 | ||
| Structural Basis for Specific, High-Affinity Tetracycline Binding by an In Vitro Evolved Aptamer and Artificial Riboswitch | Q27652608 | ||
| A Structural Basis for the Recognition of 2′-Deoxyguanosine by the Purine Riboswitch | Q27652897 | ||
| Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch | Q27653517 | ||
| The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain | Q27654015 | ||
| Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA | Q27654103 | ||
| Free State Conformational Sampling of the SAM-I Riboswitch Aptamer Domain | Q27663543 | ||
| Structural Insights into Ligand Recognition by a Sensing Domain of the Cooperative Glycine Riboswitch | Q27666293 | ||
| Thi20, a remarkable enzyme from Saccharomyces cerevisiae with dual thiamin biosynthetic and degradation activities | Q27937474 | ||
| A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes | Q28146008 | ||
| RNA-modifying enzymes | Q28208681 | ||
| Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch | Q28242477 | ||
| Structure of the S-adenosylmethionine riboswitch regulatory mRNA element | Q28249513 | ||
| Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition | Q28262834 | ||
| Structural basis of glmS ribozyme activation by glucosamine-6-phosphate | Q28264810 | ||
| Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine | Q28294025 | ||
| Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs | Q28299238 | ||
| Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways | Q28473763 | ||
| TheglmSribozyme: use of a small molecule coenzyme by a gene-regulatory RNA | Q28728642 | ||
| Molecular complexity and its impact on the probability of finding leads for drug discovery | Q30993107 | ||
| Development and application of a high-throughput assay for glmS riboswitch activators | Q33264067 | ||
| A fragment-based approach to identifying ligands for riboswitches | Q33531476 | ||
| Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis | Q33658493 | ||
| The Pyridine Analog of Thiamin and the Growth of Fungi | Q33746297 | ||
| Folding of a transcriptionally acting preQ1 riboswitch | Q33934559 | ||
| Design and antimicrobial action of purine analogues that bind Guanine riboswitches | Q34074270 | ||
| The ligand-free state of the TPP riboswitch: a partially folded RNA structure | Q34151962 | ||
| Tuning Riboswitch Regulation through Conformational Selection | Q34482382 | ||
| Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand | Q34522067 | ||
| Riboswitches as antibacterial drug targets | Q34589699 | ||
| A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes | Q35012926 | ||
| The hairpin ribozyme | Q35614124 | ||
| Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae | Q35928431 | ||
| Improving on nature: antibiotics that target the ribosome | Q36235849 | ||
| Mechanisms of resistance to an amino acid antibiotic that targets translation | Q36662633 | ||
| Forty years of in vitro evolution | Q36883743 | ||
| Engineered riboswitches: overview, problems and trends. | Q37128290 | ||
| Inhibition of RNase P RNA cleavage by aminoglycosides | Q37199561 | ||
| Biochemical features and functional implications of the RNA-based T-box regulatory mechanism | Q37405775 | ||
| Riboflavin production in Lactococcus lactis: potential for in situ production of vitamin-enriched foods | Q37572246 | ||
| Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression | Q37684735 | ||
| Ribozymes and Riboswitches: Modulation of RNA Function by Small Molecules | Q37798793 | ||
| Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain | Q38299358 | ||
| Binding of tobramycin leads to conformational changes in yeast tRNA(Asp) and inhibition of aminoacylation | Q39646643 | ||
| Formation of Pyrithiamine Pyrophosphate in Brain Tissue | Q39995863 | ||
| A stress-responsive RNA switch regulates VEGFA expression. | Q40154687 | ||
| 4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function | Q42015508 | ||
| Inhibition of the hammerhead ribozyme by neomycin. | Q43205493 | ||
| Inhibition of the self-cleavage reaction of the human hepatitis delta virus ribozyme by antibiotics | Q45769911 | ||
| The RFN riboswitch of Bacillus subtilis is a target for the antibiotic roseoflavin produced by Streptomyces davawensis | Q46068451 | ||
| Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine | Q46852870 | ||
| High-throughput-compatible assay for glmS riboswitch metabolite dependence | Q46950329 | ||
| Antibiotic inhibition of group I ribozyme function | Q47312331 | ||
| Identification of aecA mutations in Bacillus subtilis as nucleotide substitutions in the untranslated leader region of the aspartokinase II operon | Q48227029 | ||
| Antibacterial lysine analogs that target lysine riboswitches. | Q52000177 | ||
| Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch. | Q54458852 | ||
| Letter: Roseoflavin, a new antimicrobial pigment from Streptomyces. | Q55061596 | ||
| Thialysine utilization for protein synthesis by CHO cells | Q69039173 | ||
| The leader sequence of the Escherichia coli lysC gene is involved in the regulation of LysC synthesis | Q77673197 | ||
| The mode of action of pyrithiamine as an inductor of thiamine deficiency | Q78315782 | ||
| ROSEOFLAVIN, A NEW ANTIMICROBIAL PIGMENT FROM STREPTOMYCES | Q78418469 | ||
| Targeting RNA with small molecules | Q80940656 | ||
| Structure-activity studies of oxazolidinone analogs as RNA-binding agents | Q83126738 | ||
| P433 | issue | 12 | |
| P304 | page(s) | 1329-1338 | |
| P577 | publication date | 2011-05-26 | |
| P1433 | published in | Accounts of Chemical Research | Q899474 |
| P1476 | title | Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs | |
| P478 | volume | 44 |
| Q27681170 | A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch |
| Q36072316 | A glyS T-box riboswitch with species-specific structural features responding to both proteinogenic and nonproteinogenic tRNAGly isoacceptors |
| Q93170718 | A screening platform to monitor RNA processing and protein-RNA interactions in ribonuclease P uncovers a small molecule inhibitor |
| Q40396743 | Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition |
| Q27680143 | An in vitro evolved glmS ribozyme has the wild-type fold but loses coenzyme dependence |
| Q38629693 | An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system. |
| Q35830915 | Analysis of In Vitro Aptamer Selection Parameters |
| Q40381731 | Antibacterial and antivirulence effect of 6-N-hydroxylaminopurine in Listeria monocytogenes |
| Q39456622 | Antimicrobial aptamers for detection and inhibition of microbial pathogen growth. |
| Q35691198 | Atomic-level insights into metabolite recognition and specificity of the SAM-II riboswitch |
| Q28262005 | Bacterial RNA thermometers: molecular zippers and switches |
| Q35981929 | Basis for ligand discrimination between ON and OFF state riboswitch conformations: the case of the SAM-I riboswitch |
| Q28484847 | Challenges and opportunities for small molecule aptamer development |
| Q41095160 | Chemical feasibility of the general acid/base mechanism of glmS ribozyme self-cleavage |
| Q47096979 | Computational Methods for Modeling Aptamers and Designing Riboswitches |
| Q39312942 | Conformational Dynamics of mRNA in Gene Expression as New Pharmaceutical Target |
| Q38293238 | Conformational Rearrangements of Individual Nucleotides during RNA-Ligand Binding Are Rate-Differentiated |
| Q89947149 | Conscious uncoupling of riboswitch functions |
| Q28248973 | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA |
| Q34763150 | Crystallographic analysis of TPP riboswitch binding by small-molecule ligands discovered through fragment-based drug discovery approaches |
| Q91929384 | Development and Testing of the OPLS-AA/M Force Field for RNA |
| Q42367977 | Direct modulation of T-box riboswitch-controlled transcription by protein synthesis inhibitors |
| Q91304272 | Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria |
| Q90467394 | Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics |
| Q92581710 | Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations |
| Q36034458 | Factors that influence T box riboswitch efficacy and tRNA affinity. |
| Q92295886 | Fluorescence-based investigations of RNA-small molecule interactions |
| Q91733630 | Fluorescent indicator displacement assays to identify and characterize small molecule interactions with RNA |
| Q30537755 | Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. |
| Q38195069 | Genomic tools to profile antibiotic mode of action. |
| Q26998920 | Global analysis of riboswitches by small-angle X-ray scattering and calorimetry |
| Q37057446 | Glucosamine and glucosamine-6-phosphate derivatives: catalytic cofactor analogues for the glmS ribozyme |
| Q42076318 | High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions |
| Q38576441 | Identification of Spermidine Binding Site in T-box Riboswitch Antiterminator RNA. |
| Q34286207 | Identification of ligand analogues that control c-di-GMP riboswitches. |
| Q35669377 | Imaging metabolite dynamics in living cells using a Spinach-based riboswitch |
| Q43972302 | In Vivo Behavior of the Tandem Glycine Riboswitch in Bacillus subtilis |
| Q47158532 | Interactions of Protonated Guanidine and Guanidine Derivatives with Multiply Deprotonated RNA Probed by Electrospray Ionization and Collisionally Activated Dissociation |
| Q57526870 | Investigation of RNA-Ligand Interactions by 19F NMR Spectroscopy Using Fluorinated Probes |
| Q90309006 | Ligand Binding Mechanism and Its Relationship with Conformational Changes in Adenine Riboswitch |
| Q58568482 | Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing |
| Q47941828 | Ligand design for riboswitches, an emerging target class for novel antibiotics |
| Q38312449 | Ligand-induced stabilization of the aptamer terminal helix in the add adenine riboswitch. |
| Q26781454 | Linking aptamer-ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and design |
| Q38735195 | Long-Range Interactions in Riboswitch Control of Gene Expression |
| Q38316764 | Mapping the interactions of selected antibiotics and their Cu2+ complexes with the antigenomic δ ribozyme. |
| Q38325874 | Microscopic rearrangement of bound minor groove binders detected by NMR. |
| Q38771087 | Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNAGly |
| Q58708506 | Molecular mechanisms for dynamic regulation of N1 riboswitch by aminoglycosides |
| Q41974958 | Native purification and labeling of RNA for single molecule fluorescence studies |
| Q54458887 | New insights into gene regulation--high-resolution structures of cobalamin riboswitches. |
| Q33951177 | New trends in aminoglycosides use. |
| Q38083297 | Novel avenues for Clostridium difficile infection drug discovery. |
| Q34044442 | Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora |
| Q59113204 | Perspectives on the Emerging Applications of Multifaceted Biomedical Polymeric Nanomaterials |
| Q34756866 | Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch |
| Q28711956 | Phylogenetic analysis and comparative genomics of purine riboswitch distribution in prokaryotes |
| Q28654385 | Prospects for riboswitch discovery and analysis |
| Q40517162 | Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches |
| Q38301085 | RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression |
| Q27023794 | RNA quaternary structure and global symmetry |
| Q37401148 | RNA regulators responding to ribosomal protein S15 are frequent in sequence space |
| Q27022554 | RNA tectonics (tectoRNA) for RNA nanostructure design and its application in synthetic biology |
| Q36392455 | Rapid RNA-ligand interaction analysis through high-information content conformational and stability landscapes |
| Q37336975 | Rational design of a synthetic mammalian riboswitch as a ligand-responsive -1 ribosomal frame-shifting stimulator |
| Q26744202 | Recent Advances in Developing Small Molecules Targeting Nucleic Acid |
| Q34694681 | Recognition of nucleic acid junctions using triptycene-based molecules. |
| Q98226239 | Riboflow: Using Deep Learning to Classify Riboswitches With ∼99% Accuracy |
| Q46386482 | Riboswitch diversity and distribution |
| Q38060778 | Riboswitch-based antibacterial drug discovery using high-throughput screening methods |
| Q38491740 | SMMRNA: a database of small molecule modulators of RNA. |
| Q33914930 | Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer |
| Q48152614 | Small Molecule Recognition Triggers Secondary and Tertiary Interactions in DNA Folding and Hammerhead Ribozyme Catalysis |
| Q36198639 | Small molecule fluoride toxicity agonists |
| Q58802698 | Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting |
| Q28239535 | Structure and function of preQ1 riboswitches |
| Q27677362 | Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold |
| Q28656519 | Structure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs |
| Q58550160 | Superior cellular activities of azido- over amino-functionalized ligands for engineered preQ riboswitches in E.coli |
| Q34712050 | Synergetic regulation of translational reading-frame switch by ligand-responsive RNAs in mammalian cells |
| Q90170336 | Synthetic small-molecule RNA ligands: future prospects as therapeutic agents |
| Q59349013 | Targeting RNA in mammalian systems with small molecules |
| Q89529120 | The Non-Coding RNA Landscape of Plasma Cell Dyscrasias |
| Q53131965 | The effects of α-lipoic acid against testicular ischemia-reperfusion injury in Rats. |
| Q34228096 | The expanding view of RNA and DNA function |
| Q34723238 | The genetic code as expressed through relationships between mRNA structure and protein function |
| Q27324546 | The impact of a ligand binding on strand migration in the SAM-I riboswitch |
| Q30544038 | Tuning a riboswitch response through structural extension of a pseudoknot. |
| Q93074975 | Unveiling the druggable RNA targets and small molecule therapeutics |
| Q27683543 | Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically |
| Q38070780 | Viable screening targets related to the bacterial cell wall. |
| Q27703133 | What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch |
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