p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair

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p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201104053
P932PMC publication ID3198158
P698PubMed publication ID21987635
P5875ResearchGate publication ID51707217

P50authorPura Muñoz CánovesQ23505252
Eusebio PerdigueroQ37372283
P2093author name stringAntonio L Serrano
Mercè Jardí
Carme Caelles
Vanessa Ruiz-Bonilla
Pedro Sousa-Victor
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A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repairQ24652669
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylationQ28363102
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblastsQ28511032
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophagesQ28568915
Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathwayQ41298517
MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in miceQ41881288
Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock.Q42205530
Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathwayQ48022280
Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts.Q52199834
Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity.Q53614203
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiationQ61776576
Suturing versus immobilization of a muscle laceration. A morphological and functional study in a mouse modelQ74669853
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21Q28975612
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
Wound repair and regenerationQ29617949
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesisQ29622851
Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinomaQ33454083
Inflammation and oncogenesis: a vicious connectionQ33653294
Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophagesQ33710188
MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophyQ34017116
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosisQ34044475
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.Q34130311
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21.Q34271727
Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responsesQ34479244
Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferationQ35672032
Inflammatory processes in muscle injury and repairQ36001988
uPA deficiency exacerbates muscular dystrophy in MDX miceQ36119288
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shockQ36227887
Regulation of innate immune response by MAP kinase phosphatase-1Q36389293
The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expressionQ36983159
High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunityQ36990574
Macrophage activation by endogenous danger signalsQ37045743
Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophyQ37090043
Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in miceQ37143384
MAP kinase phosphatase-1, a critical negative regulator of the innate immune responseQ37186699
The role of PTEN signaling perturbations in cancer and in targeted therapyQ37270446
Interrelation of immunity and tissue repair or regenerationQ37459309
miR-21 as a key regulator of oncogenic processesQ37554678
Signal integration by JNK and p38 MAPK pathways in cancer developmentQ37560607
p38(MAPK): stress responses from molecular mechanisms to therapeuticsQ37576462
Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.Q37596057
The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer.Q37693586
Phagocyte partnership during the onset and resolution of inflammation.Q37760424
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathwayQ40446884
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cellsQ40726959
Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinasesQ41079552
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P1104number of pages16
P304page(s)307-322
P577publication date2011-10-10
P1433published inJournal of Cell BiologyQ1524550
P1476titlep38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair
P478volume195

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