| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2014PLoSO...9k3232L |
| P356 | DOI | 10.1371/JOURNAL.PONE.0113232 |
| P932 | PMC publication ID | 4232525 |
| P698 | PubMed publication ID | 25398078 |
| P5875 | ResearchGate publication ID | 268281461 |
| P2093 | author name string | Clifford L Wang | |
| Joshua P Ferreira | |||
| Ingrid E B Lawhorn | |||
| P2860 | cites work | CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes | Q21508827 |
| RNA-guided human genome engineering via Cas9 | Q24598394 | ||
| Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system | Q37214501 | ||
| Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. | Q37420333 | ||
| Transcriptional and epigenetic regulation of the p53 tumor suppressor gene | Q37911180 | ||
| Unravelling mechanisms of p53-mediated tumour suppression | Q38205099 | ||
| RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repair | Q39719255 | ||
| Knockdown of human p53 gene expression in 293-T cells by retroviral vector-mediated short hairpin RNA. | Q40354775 | ||
| Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells | Q41154447 | ||
| The bidirectional p53-Wrap53β promoter is controlled by common cis- and trans-regulatory elements | Q42808158 | ||
| Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage. | Q44049541 | ||
| Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. | Q52423088 | ||
| Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas | Q24606465 | ||
| Multiplex genome engineering using CRISPR/Cas systems | Q24609428 | ||
| Efficient genome editing in zebrafish using a CRISPR-Cas system | Q24610828 | ||
| DBTSS: DataBase of Transcriptional Start Sites progress report in 2012 | Q24619908 | ||
| CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes | Q24625361 | ||
| CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III | Q24628207 | ||
| RNA-guided editing of bacterial genomes using CRISPR-Cas systems | Q24630389 | ||
| Protospacer recognition motifs: mixed identities and functional diversity | Q24632944 | ||
| A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity | Q24669850 | ||
| A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
| RNA-programmed genome editing in human cells | Q28044562 | ||
| RNA-guided gene activation by CRISPR-Cas9-based transcription factors | Q28295458 | ||
| KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading | Q28473103 | ||
| One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering | Q29547524 | ||
| Characteristics of a human cell line transformed by DNA from human adenovirus type 5 | Q29547863 | ||
| RNA-guided genetic silencing systems in bacteria and archaea | Q29614421 | ||
| Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system | Q29615782 | ||
| Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression | Q29615784 | ||
| High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells | Q29616045 | ||
| CRISPR RNA–guided activation of endogenous human genes | Q29617072 | ||
| CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea | Q29617488 | ||
| Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. | Q30458169 | ||
| DBTSS: DataBase of human Transcriptional Start Sites and full-length cDNAs | Q30782690 | ||
| Standardization of real-time PCR gene expression data from independent biological replicates | Q31155611 | ||
| Massive transcriptional start site analysis of human genes in hypoxia cells | Q33411670 | ||
| Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells | Q34039369 | ||
| Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells | Q34093413 | ||
| Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system | Q34350509 | ||
| CRISPR interference (CRISPRi) for sequence-specific control of gene expression | Q34378409 | ||
| Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers | Q34489634 | ||
| Modulating ectopic gene expression levels by using retroviral vectors equipped with synthetic promoters | Q34498152 | ||
| Tuning gene expression with synthetic upstream open reading frames | Q34782511 | ||
| Short motif sequences determine the targets of the prokaryotic CRISPR defence system | Q34953078 | ||
| Target specificity of the CRISPR-Cas9 system. | Q35114320 | ||
| The VP16 paradox: herpes simplex virus VP16 contains a long-range activation domain but within the natural multiprotein complex activates only from promoter-proximal positions | Q35889925 | ||
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity | Q37196274 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| P304 | page(s) | e113232 | |
| P577 | publication date | 2014-11-14 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Evaluation of sgRNA target sites for CRISPR-mediated repression of TP53 | |
| P478 | volume | 9 |
| Q99632470 | Aptamer-mediated reversible transactivation of gene expression by light |
| Q26775746 | Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation |
| Q39014648 | CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes |
| Q90280381 | CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein |
| Q89873570 | CRISPR/Cas9-mediated genome editing: From basic research to translational medicine |
| Q38614582 | CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer |
| Q55097609 | Design principles for nuclease-deficient CRISPR-based transcriptional regulators. |
| Q26765901 | Emerging Technologies to Create Inducible and Genetically Defined Porcine Cancer Models |
| Q92663586 | Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects |
| Q90392618 | Evaluation of the CRISPR/Cas9 directed mutant TP53 gene repairing effect in human prostate cancer cell line PC-3 |
| Q33777855 | Genetic and epigenetic control of gene expression by CRISPR-Cas systems |
| Q47604870 | Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9. |
| Q94517912 | Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31 |
| Q93162035 | Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements |
| Q37639765 | Progress in Genome Editing Technology and Its Application in Plants |
| Q47235195 | Role of the CRISPR system in controlling gene transcription and monitoring cell fate (Review). |
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