The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.

scientific article

The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JSB.2014.10.007
P932PMC publication ID4400868
P698PubMed publication ID25449314
P5875ResearchGate publication ID267572229

P50authorWendy ShawQ56669217
Garry W BuchkoQ56808207
P2093author name stringSusan Krueger
Nasib Karl Maluf
John S Philo
Barbara J Tarasevich
Genyao Lin
P2860cites workModern analytical ultracentrifugation in protein science: a tutorial reviewQ24645050
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Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontinQ28143303
Amelogenin-deficient mice display an amelogenesis imperfecta phenotypeQ28201910
Protein interactions during assembly of the enamel organic extracellular matrixQ28586894
A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chlorideQ28910184
A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein)Q28910191
The leucine rich amelogenin protein (LRAP) adsorbs as monomers or dimers onto surfaces.Q30475727
Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscaleQ30503764
Specific amelogenin gene splice products have signaling effects on cells in culture and in implants in vivoQ30656624
Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptidesQ33178995
The tooth enamel protein, porcine amelogenin, is an intrinsically disordered protein with an extended molecular configuration in the monomeric formQ33411458
The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotypeQ33666402
The structural biology of the developing dental enamel matrixQ33707684
Amelogenins: assembly, processing and control of crystal morphologyQ34375929
Partial high-resolution structure of phosphorylated and non-phosphorylated leucine-rich amelogenin protein adsorbed to hydroxyapatiteQ35161638
Dissecting amelogenin protein nanospheres: characterization of metastable oligomersQ35266477
The Amelogenin Proteins and Enamel Development in Humans and MiceQ35639526
Rescue of the murine amelogenin null phenotype with two amelogenin transgenesQ35727312
Effect of phosphorylation on the interaction of calcium with leucine-rich amelogenin peptideQ36251080
Phosphorylation and ionic strength alter the LRAP-HAP interface in the N-terminusQ36765783
Neutron reflectometry studies of the adsorbed structure of the amelogenin, LRAP.Q36789990
The nucleation and growth of calcium phosphate by amelogeninQ37004210
Phosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition.Q37285119
Leucine rich amelogenin peptide alters ameloblast differentiation in vivoQ37315627
Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathwayQ37378529
Leucine-rich amelogenin peptides regulate mineralization in vitroQ38363618
The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expressionQ39526669
Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregatesQ39973841
Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitroQ40119310
The chemistry of enamel development.Q40454870
Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesisQ40509614
The role of enamel matrix proteins in the development of cementum and periodontal tissuesQ41504115
Self-assembly properties of recombinant engineered amelogenin proteins analyzed by dynamic light scattering and atomic force microscopyQ41756111
Mmp-20 and Klk4 cleavage site preferences for amelogenin sequencesQ42566135
Determination of the conformations of cAMP receptor protein and its T127L,S128A mutant with and without cAMP from small angle neutron scattering measurementsQ42682048
Leucine-rich amelogenin peptide induces osteogenesis in mouse embryonic stem cellsQ43089632
Interaction of amelogenin with hydroxyapatite crystals: an adherence effect through amelogenin molecular self-associationQ43770312
Detection of monodisperse aggregates of a recombinant amelogenin by dynamic light scatteringQ43970002
Self-assembly and effect on crystal growth of the leucine-rich amelogenin peptideQ44604289
Evidence for amelogenin "nanospheres" as functional components of secretory-stage enamel matrix.Q44987880
The COOH terminus of the amelogenin, LRAP, is oriented next to the hydroxyapatite surfaceQ45010264
Temperature and pH-dependent supramolecular self-assembly of amelogenin molecules: a dynamic light-scattering analysisQ46065009
The effect of LRAP on enamel organ epithelial cell differentiationQ46066754
Quantitative analysis of amelogenin solubilityQ46164076
Enamel formation in vitro in mouse molar explants exposed to amelogenin polypeptides ATMP and LRAP on enamel developmentQ46206686
Comparative calcium binding of leucine-rich amelogenin peptide and full-length amelogeninQ46281839
Differential effect of amelogenin peptides on osteogenic differentiation in vitro: identification of possible new drugs for bone repair and regenerationQ46291658
Analysis of amelogenin proteins using monospecific antibodies to defined sequencesQ46294980
Ten-year results following treatment of intra-bony defects with enamel matrix proteins and guided tissue regenerationQ47438287
Comparison of the crystal and solution structures of calmodulin and troponin CQ48112277
Identification of the leucine-rich amelogenin peptide (LRAP) as the translation product of an alternatively spliced transcriptQ48235654
Cyclical changes in pH in bovine developing enamel as sequential bands.Q50875205
Improved methods for fitting sedimentation coefficient distributions derived by time-derivative techniques.Q51940791
Properties of dissociatively extracted fetal tooth matrix proteins. I. Principal molecular species in developing bovine enamelQ71364245
Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defectsQ73732983
P433issue1
P304page(s)81-91
P577publication date2014-10-25
P1433published inJournal of Structural BiologyQ3186947
P1476titleThe leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution
P478volume190

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cites work (P2860)
Q55559827Amelogenin is a Potential Biomarker for the Aggressiveness in Odontogenic Tumors
Q47166228Dose-Dependent Rescue of KO Amelogenin Enamel by Transgenes in Vivo
Q46276385Dynamic interactions of amelogenin with hydroxyapatite surfaces are dependent on protein phosphorylation and solution pH.
Q89365381Identification of major matrix metalloproteinase-20 proteolytic processing products of murine amelogenin and tyrosine-rich amelogenin peptide using a nuclear magnetic resonance spectroscopy based method
Q33849604Protein Phosphorylation and Mineral Binding Affect the Secondary Structure of the Leucine-Rich Amelogenin Peptide

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