scholarly article | Q13442814 |
P50 | author | Maximilian Mossner | Q52904409 |
Richard B Lock | Q61292565 | ||
Motohiro Kato | Q40858840 | ||
P2093 | author name string | Glenn M Marshall | |
Wolf-Karsten Hofmann | |||
H Phillip Koeffler | |||
Seishi Ogawa | |||
Daniel Nowak | |||
Nils H Thoennissen | |||
Ryoko Okamoto | |||
Tadayuki Akagi | |||
Masashi Sanada | |||
Norihiko Kawamata | |||
Johann C Jann | |||
Marion Klaumünzer | |||
Natalia L M Liem | |||
Rachael A Papa | |||
Verena Nowak | |||
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Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia. | Q46170702 | ||
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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros | Q57734316 | ||
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The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse | Q74097949 | ||
Identification and characterization of genetic variation in the folylpolyglutamate synthase gene | Q81310207 | ||
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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. | Q27852067 | ||
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Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2 | Q33521938 | ||
Novel in vivo model of inducible multi-drug resistance in acute lymphoblastic leukemia with chromosomal translocation t(4;11) | Q34005240 | ||
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Acute lymphoblastic leukemia cells that survive combination chemotherapy in vivo remain sensitive to allogeneic immune effects | Q34634251 | ||
Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line | Q34652639 | ||
Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse | Q35102275 | ||
Substrate cycles and drug resistance to 1-beta-D-arabinofuranosylcytosine (araC). | Q35994964 | ||
Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group | Q36058255 | ||
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Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia | Q36969782 | ||
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Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells | Q37878174 | ||
Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines. | Q38359462 | ||
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Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells | Q40410731 | ||
Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies | Q40533053 | ||
Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase | Q40873521 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lymphoblastic leukemia | Q18553852 |
drug resistance | Q12147416 | ||
xenograft | Q64148587 | ||
P304 | page(s) | 32-43.e1-35 | |
P577 | publication date | 2014-10-29 | |
P1433 | published in | Experimental Hematology | Q5421109 |
P1476 | title | Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance | |
P478 | volume | 43 |
Q37645045 | A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts |
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Q42287089 | Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML |
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