Lack of pharmacokinetic interactions between pitavastatin and efavirenz or darunavir/ritonavir

scientific article published on December 2014

Lack of pharmacokinetic interactions between pitavastatin and efavirenz or darunavir/ritonavir is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1097/QAI.0000000000000333
P932PMC publication ID4404408
P698PubMed publication ID25202920

P50authorJames A UnderbergQ37831367
P2093author name stringQing Ma
Judith A Aberg
Gene D Morse
Carlos D Malvestutto
P2860cites workPitavastatin in cardiometabolic disease: therapeutic profileQ21246037
Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.Q34094825
Drug-drug interaction between pitavastatin and various drugs via OATP1B1.Q34566306
Pharmacokinetic interaction between nelfinavir and pravastatin in HIV-seronegative volunteers: ACTG Study A5108.Q34599850
The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.Q34613443
Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitorsQ36544977
Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humansQ36687277
Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugsQ37481450
Drug-drug interactions between HMG-CoA reductase inhibitors (statins) and antiviral protease inhibitors.Q38109095
Statin myotoxicity: a review of genetic susceptibility factorsQ38157284
Induction of multiple drug transporters by efavirenzQ39880991
Effects of steady-state lopinavir/ritonavir on the pharmacokinetics of pitavastatin in healthy adult volunteersQ42649723
Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047.Q42671235
Simvastatin-nelfinavir interaction implicated in rhabdomyolysis and deathQ44200949
Integration of atazanavir into an existing liquid chromatography UV method for protease inhibitors: validation and applicationQ44208340
Quality assurance program for pharmacokinetic assay of antiretrovirals: ACTG proficiency testing for pediatric and adult pharmacology support laboratories, 2003 to 2004: a requirement for therapeutic drug monitoringQ46121532
Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 StudyQ46568560
Primary care guidelines for the management of persons infected with HIV: 2013 update by the HIV medicine association of the Infectious Diseases Society of America.Q51859231
Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatinQ95423232
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectritonavirQ422618
efavirenzQ422645
pharmacokineticsQ323936
P304page(s)390-396
P577publication date2014-12-01
P1433published inJournal of Acquired Immune Deficiency SyndromesQ6294722
P1476titleLack of pharmacokinetic interactions between pitavastatin and efavirenz or darunavir/ritonavir
P478volume67

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cites work (P2860)
Q41996857A review of drug-drug interactions in older HIV-infected patients
Q88874091Benefits and Risks of Statin Therapy in the HIV-Infected Population
Q38881481Clinical benefits of pitavastatin: focus on patients with diabetes or at risk of developing diabetes
Q40311279Effects of pitavastatin and pravastatin on markers of immune activation and arterial inflammation in HIV.
Q42656331Evidence-based review of statin use in patients with HIV on antiretroviral therapy
Q40162393HIV-Related Cardiovascular Disease, Statins, and the REPRIEVE Trial.
Q95925630Intestinal P-gp and Putative Hepatic OATP1B Induction: ITC Perspective on Drug Development Implications
Q50915503Lipid-Lowering Therapy in HIV-Infected Patients: Relationship with Antiretroviral Agents and Impact of Substance-Related Disorders.
Q37038775Pathophysiology and management of cardiovascular disease in patients with HIV
Q40239735Pitavastatin versus pravastatin in adults with HIV-1 infection and dyslipidaemia (INTREPID): 12 week and 52 week results of a phase 4, multicentre, randomised, double-blind, superiority trial
Q39212423Recommendations for Managing Drug-Drug Interactions with Statins and HIV Medications
Q36399904Statins to improve cardiovascular outcomes in treated HIV infection

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