Novel methylation markers of the dysexecutive-psychiatric phenotype in FMR1 premutation women

scientific article published on 25 March 2015

Novel methylation markers of the dysexecutive-psychiatric phenotype in FMR1 premutation women is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1212/WNL.0000000000001496
P932PMC publication ID4409583
P698PubMed publication ID25809302

P50authorKim CornishQ1741621
Darren R HockingQ89285729
Alison D ArchibaldQ101147543
Yoshimi InabaQ123050466
Howard R SlaterQ123050473
Mark A. BellgroveQ30537281
Minh BuiQ39063603
Julian N. TrollorQ46612412
Erin TurbittQ56923501
David E GodlerQ56996913
Sylvia A MetcalfeQ64834125
Claudine KraanQ86064363
P2093author name stringJonathan Cohen
Xin Li
P2860cites workEpigenetic programming by maternal behaviorQ27860466
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicingQ28249503
Transcription-associated R-loop formation across the human FMR1 CGG-repeat regionQ28537978
Epigenetic regulation in psychiatric disordersQ29616296
Methylation of novel markers of fragile X alleles is inversely correlated with FMRP expression and FMR1 activation ratio.Q33527737
Evidence for the toxicity of bidirectional transcripts and mitochondrial dysfunction in blood associated with small CGG expansions in the FMR1 gene in patients with parkinsonismQ33617809
CNS expression of murine fragile X protein (FMRP) as a function of CGG-repeat size.Q33649307
FMR1 intron 1 methylation predicts FMRP expression in blood of female carriers of expanded FMR1 allelesQ33949054
An information-rich CGG repeat primed PCR that detects the full range of fragile X expanded alleles and minimizes the need for southern blot analysisQ34084834
Premature ovarian failure in the fragile X syndromeQ34306135
The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety InventoriesQ34309145
Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndromeQ34407383
FMR1 epigenetic silencing commonly occurs in undifferentiated fragile X-affected embryonic stem cellsQ34530652
Social phobiaQ34559590
FMR1 CGG repeat length predicts motor dysfunction in premutation carriers.Q34721602
CGG-repeat length threshold for FMR1 RNA pathogenesis in a cellular model for FXTASQ34955465
R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.Q35160930
Prevalence of CGG expansions of the FMR1 gene in a US population-based sampleQ36082674
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellumQ36450321
Anxiety and cognitive performance: attentional control theoryQ36828105
DNA methylation in mouse embryonic stem cells and development.Q37024892
Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.Q37503306
Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndromeQ37508604
Neurobehavioural evidence for the involvement of the FMR1 gene in female carriers of fragile X syndromeQ38076961
Fragile X-related element 2 methylation analysis may provide a suitable option for inclusion of fragile X syndrome and/or sex chromosome aneuploidy into newborn screening: a technical validation studyQ39260899
Cognitive-motor interference during postural control indicates at-risk cerebellar profiles in females with the FMR1 premutationQ39376126
CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locusQ40789249
Integrating Mediators and Moderators in Research Design.Q42023875
CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndromeQ42068973
Fragile X mental retardation 1 (FMR1) intron 1 methylation in blood predicts verbal cognitive impairment in female carriers of expanded FMR1 alleles: evidence from a pilot study.Q44610465
Analysis of the molecular parameters that could predict the risk of manifesting premature ovarian failure in female premutation carriers of fragile X syndromeQ45061560
Mood and anxiety disorders in females with the FMR1 premutationQ45582526
Impaired response inhibition is associated with self-reported symptoms of depression, anxiety, and ADHD in female FMR1 premutation carriers.Q46708960
Early detection of fragile X syndrome: applications of a novel approach for improved quantitative methylation analysis in venous blood and newborn blood spotsQ46853263
Genotype-phenotype relationship in female carriers of the premutation and full mutation of FMR-1.Q50301648
Risk of cognitive impairment in female premutation carriers of fragile X premutation: analysis by means of robust segmented linear regression models.Q51697962
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein.Q51731749
Genotype, molecular phenotype, and cognitive phenotype: correlations in fragile X syndrome.Q51985536
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
P304page(s)1631-1638
P577publication date2015-03-25
P1433published inNeurologyQ1161692
P1476titleNovel methylation markers of the dysexecutive-psychiatric phenotype in FMR1 premutation women
P478volume84

Reverse relations

cites work (P2860)
Q90950470Abnormally Methylated FMR1 in Absence of a Detectable Full Mutation in a U.S.A Patient Cohort Referred for Fragile X Testing
Q28087781Advanced technologies for the molecular diagnosis of fragile X syndrome
Q49813454An emerging role for epigenetic factors in relation to executive function.
Q37622638Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females.
Q92934722Clinical and Molecular Differences between 4-Year-Old Monozygous Male Twins Mosaic for Normal, Premutation and Fragile X Full Mutation Alleles
Q46017813Clinical and molecular correlates in fragile X premutation females.
Q40776996Executive Dysfunction in Female FMR1 Premutation Carriers.
Q64068791Incomplete silencing of full mutation alleles in males with fragile X syndrome is associated with autistic features
Q50301216Intragenic DNA methylation in buccal epithelial cells and intellectual functioning in a paediatric cohort of males with fragile X.
Q92203559Language processing skills linked to FMR1 variation: A study of gaze-language coordination during rapid automatized naming among women with the FMR1 premutation
Q38880543Neuropsychiatry of fragile X-premutation carriers with and without fragile X-associated tremor-ataxia syndrome: implications for neuropsychology
Q33629743Reduced vagal tone in women with the FMR1 premutation is associated with FMR1 mRNA but not depression or anxiety.
Q47297403The effects of optimism, religion, and hope on mood and anxiety disorders in women with the FMR1 premutation.
Q36522702Trajectory and Predictors of Depression and Anxiety Disorders in Mothers With the FMR1 Premutation
Q37076523β-glucuronidase mRNA levels are correlated with gait and working memory in premutation females: understanding the role of FMR1 premutation alleles

Search more.