Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis

scientific article published on 17 October 2006

Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1189/JLB.0606402
P932PMC publication ID1748426
P698PubMed publication ID17046971
P5875ResearchGate publication ID6748600

P2093author name stringKemin Chen
Helen Braley-Mullen
Yongzhong Wei
Gordon C Sharp
P2860cites workInflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cellsQ28203099
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosisQ28307643
Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammationQ28589039
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Q29547855
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.Q30436326
Tumor necrosis factor-alpha overexpression in lung disease: a single cause behind a complex phenotypeQ30489186
Adoptive transfer murine model of granulomatous experimental autoimmune thyroiditisQ34112877
Regulation of lymphocyte proliferation and death by FLIP.Q34572136
The myofibroblast in pulmonary fibrosisQ35022198
Treating Crohn's disease by inducing T lymphocyte apoptosisQ35027223
Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healingQ35088370
The biology of TNF blockadeQ35556360
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosisQ35750477
Interleukin-12 promotes activation of effector cells that induce a severe destructive granulomatous form of murine experimental autoimmune thyroiditis.Q35765389
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transductionQ35918894
Severe inflammatory arthritis and lymphadenopathy in the absence of TNF.Q36028645
TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal modelsQ36028736
Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditisQ36259466
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosisQ36356708
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic processQ36363681
Effects of natural or synthetic microbial adjuvants on induction of autoimmune thyroiditisQ37050750
IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell deathQ38303234
Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis.Q38309766
Immune mechanisms in autoimmune thyroiditisQ38692992
Periportal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFN-gamma, high TNF-alpha, or low RANTES, depending on age and genderQ38882456
T-cell regulation in autoimmune thyroiditisQ40260753
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin productionQ40849898
Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization studyQ41782250
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responsesQ44158655
Inhibition of TGFbeta1 by anti-TGFbeta1 antibody or lisinopril reduces thyroid fibrosis in granulomatous experimental autoimmune thyroiditisQ44223917
Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosisQ44248148
Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-betaQ44484392
Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6.Q45025149
Induction of granulomatous experimental autoimmune thyroiditis in IL-4 gene-disrupted mice.Q52530267
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.Q54150165
Induction of experimental autoimmune thyroiditis in mice with in vitro activated splenic T cells.Q54449501
Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: Extended reportQ57350112
Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritisQ60461810
Cytotoxicity of tumor necrosis factor for thyroid epithelial cells and its regulation by interferon-gammaQ70370051
TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosisQ71151702
TNF-alpha-mediated lung cytokine networking and eosinophil recruitment in pulmonary fibrosisQ71968405
Regulation of the induction and resolution of granulomatous experimental autoimmune thyroiditis in mice by CD8+ T cellsQ72269710
Elevated serum tumor necrosis factor-alpha levels in patients with systemic sclerosis: association with pulmonary fibrosisQ73218951
The temporal importance of TNFalpha expression in the development of diabetesQ73867591
Clinical response of rheumatoid arthritis-associated pulmonary fibrosis to tumor necrosis factor-alpha inhibitionQ74775715
Expression and regulation of Fas and Fas ligand on thyrocytes and infiltrating cells during induction and resolution of granulomatous experimental autoimmune thyroiditisQ77198744
c-FLIP efficiently rescues TRAF-2-/- cells from TNF-induced apoptosisQ77628122
Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritisQ77628816
A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditisQ77671535
The kinetics of cytokine gene expression in the thyroids of mice developing granulomatous experimental autoimmune thyroiditisQ77759646
Tumour necrosis factor-alpha is a fundamental cytokine in autoimmune thyroid disease induced by thyroglobulin and lipopolysaccharide in interleukin-12 p40 deficient C57BL/6 miceQ78766578
Mechanisms of spontaneous resolution versus fibrosis in granulomatous experimental autoimmune thyroiditisQ79317508
Balance of proliferation and cell death between thyrocytes and myofibroblasts regulates thyroid fibrosis in granulomatous experimental autoimmune thyroiditis (G-EAT)Q80984651
Fas ligand is required for resolution of granulomatous experimental autoimmune thyroiditisQ81111509
T(H)-17: a giant step from T(H)1 and T(H)2Q81381452
Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alphaQ81512331
P433issue1
P304page(s)306-314
P577publication date2006-10-17
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleDecreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis
P478volume81

Reverse relations

cites work (P2860)
Q37087995A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis
Q35585036A rare case showing subacute thyroiditis-like symptoms with amyloid goiter after anti-tumor necrosis factor therapy
Q42054432Agonistic anti-CD40 promotes early development and increases the incidence of severe thyroid epithelial cell hyperplasia (TEC H/P) in CD4-/- mice
Q38642343Are thyroid nodules associated with sex-related hormones? A cross-sectional SPECT-China study
Q38271810Autoimmune thyroid disease and rheumatoid arthritis: relationship and the role of genetics
Q35758889CD8+ T cells induce thyroid epithelial cell hyperplasia and fibrosis
Q33859990Comparison of sensitivity of Th1, Th2, and Th17 cells to Fas-mediated apoptosis
Q35168021Effect of transgenic overexpression of FLIP on lymphocytes on development and resolution of experimental autoimmune thyroiditis
Q43257498Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice
Q37134327Evaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary Fibrosis
Q38730457Hepatitis C Virus E2 Protein Induces Upregulation of IL-8 Pathways and Production of Heat Shock Proteins in Human Thyroid Cells
Q91048599Human dendritic cell-specific ICAM-3-grabbing non-integrin downstream signaling alleviates renal fibrosis via Raf-1 activation in systemic candidiasis
Q92431752IS SALUSIN-ALPHA A NEW MARKER OF CARDIOVASCULAR DISEASE RISK IN HYPOTHYROIDISM?
Q46681137Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Q36691088Interleukin-10 promotes resolution of granulomatous experimental autoimmune thyroiditis
Q34783489Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NFκB activation in the foreign body response
Q50050669Mechanistic insight into beta-carotene-mediated protection against ulcerative colitis-associated local and systemic damage in mice
Q35781415Murine FLIP transgene expressed on thyroid epithelial cells promotes resolution of granulomatous experimental autoimmune thyroiditis in DBA/1 mice.
Q48178007Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
Q37072816Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.
Q35294492Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity
Q46821870Subacute painful thyroiditis accompanied by scrub typhus infection
Q35820734Th17 cells in human disease.
Q46407865The antifibrogenic effect of etanercept on development of liver cirrhosis induced by thioacetamide in rats.
Q34722403The promotion of functional urinary bladder regeneration using anti-inflammatory nanofibers
Q47097488Thyroid disorders in patients with newly diagnosed rheumatoid arthritis is associated with poor initial treatment response evaluated by disease activity score in 28 joints-C-reactive protein (DAS28-CRP): An observational cohort study
Q47733085Thyroid involvement in ankylosing spondylitis and relationship of thyroid dysfunction with anti-TNF α treatment
Q35329016Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection

Search more.