Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen

scientific article published on 21 February 2015

Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ABB.2015.02.014
P932PMC publication ID4412315
P698PubMed publication ID25712221

P2093author name stringValeriy V Smirnov
Ayodele O Kolawole
Ian M Chrisman
Brian P Hixon
Laura S Dameron
P2860cites workCrystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenaseQ28115622
A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitorsQ28237835
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptorQ28249782
1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenaseQ28333967
Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxiaQ33798508
Heme-Containing OxygenasesQ34114428
Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivoQ34320598
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.Q34394487
Heme enzyme structure and functionQ34396417
Redox and spectroscopic properties of human indoleamine 2,3-dioxygenase and a His303Ala variant: implications for catalysisQ34462364
Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspectsQ34535629
Regulation of IDO activity by oxygen supply: inhibitory effects on antimicrobial and immunoregulatory functionsQ34722824
Reassessment of the reaction mechanism in the heme dioxygenases.Q34960294
The expanded biology of serotoninQ34993925
Evidence for a ferryl intermediate in a heme-based dioxygenase.Q35006504
Indoleamine 2,3 dioxygenase and regulation of T cell immunityQ36255493
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.Q36973676
NADH oxidase activity of indoleamine 2,3-dioxygenaseQ38673283
Inhibitory substrate binding site of human indoleamine 2,3-dioxygenaseQ39948793
Indoleamine 2,3-dioxygenase. Kinetic studies on the binding of superoxide anion and molecular oxygen to enzymeQ40217520
The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenaseQ41173924
Spectroscopic studies of ligand and substrate binding to human indoleamine 2,3-dioxygenaseQ41842668
Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 1. Norharman and 4-phenylimidazole binding to the enzyme as inhibitors and heme ligandsQ42199358
Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 2. Evidence for the existence of another binding site in the enzyme for indole derivative effectorsQ42199359
The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinaseQ42588021
Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopyQ42734142
In vitro modulation of cytochrome P450 reductase supported indoleamine 2,3-dioxygenase activity by allosteric effectors cytochrome b(5) and methylene blueQ43153054
Enzyme activities involved in tryptophan metabolism along the kynurenine pathway in rabbitsQ43691769
Novel protein modification by kynurenine in human lensesQ43811221
The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenaseQ44577588
The roles of superoxide anion and methylene blue in the reductive activation of indoleamine 2,3-dioxygenase by ascorbic acid or by xanthine oxidase-hypoxanthineQ45006905
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cellsQ46734158
Relevance of free tryptophan in serum to tissue tryptophan concentrationsQ48502802
Human lens coloration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxy-kynurenine O-beta-D-glucoside.Q50515936
Spectroscopic and equilibrium properties of the indoleamine 2,3-dioxygenase-tryptophan-O2 ternary complex and of analogous enzyme derivatives. Tryptophan binding to ferrous enzyme adducts with dioxygen, nitric oxide, and carbon monoxide.Q50907206
Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes.Q50978363
Substrate Inhibition in Human Indoleamine 2,3-Dioxygenase.Q53065949
Recombinant human erythrocyte cytochrome b5.Q54627159
Simultaneous measurement of serum tryptophan and kynurenine by HPLCQ61906305
The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathwayQ68528934
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell culturesQ69005518
Indoleamine 2,3-dioxygenase. Equilibrium studies of the tryptophan binding to the ferric, ferrous, and CO-bound enzymesQ71133159
The oxygenated form of L-tryptophan 2,3-dioxygenase as reaction intermediateQ71571885
Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2,3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesisQ82253873
Cytochrome b(5) is a major reductant in vivo of human indoleamine 2,3-dioxygenase expressed in yeastQ83015185
Resonance Raman study on the oxygenated and the ferryl-oxo species of indoleamine 2,3-dioxygenase during catalytic turnoverQ83414265
Turn off the IDO: will clinical trials be successful?Q84780721
P407language of work or nameEnglishQ1860
P304page(s)47-57
P577publication date2015-02-21
P1433published inArchives of Biochemistry and BiophysicsQ635818
P1476titleCatalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen
P478volume570

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cites work (P2860)
Q42316481A short history of heme dioxygenases: rise, fall and rise again
Q49279893Different Mechanisms of Catalytic Complex Formation in Two L-Tryptophan Processing Dioxygenases
Q39093352Prostate cancer immunotherapy, particularly in combination with androgen deprivation or radiation treatment. Customized pharmacogenomic approaches to overcome immunotherapy cancer resistance.