Structural Insight Into Functional Aspects of Ribosomal RNA Targeting

scientific article published on October 6, 2003

Structural Insight Into Functional Aspects of Ribosomal RNA Targeting is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/CBIC.200300683
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcbic.200300683
https://onlinelibrary.wiley.com/doi/full/10.1002/cbic.200300683
P698PubMed publication ID14523918
P5875ResearchGate publication ID9067855

P50authorAda YonathQ7426
P2860cites workProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
The complete atomic structure of the large ribosomal subunit at 2.4 A resolutionQ27626400
The structural basis of ribosome activity in peptide bond synthesisQ27626414
Crystal structure of the ribosome at 5.5 A resolutionQ27630949
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteriaQ27635569
High resolution structure of the large ribosomal subunit from a mesophilic eubacteriumQ27636568
The structures of four macrolide antibiotics bound to the large ribosomal subunitQ27639442
L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycinQ27639641
Selection of tRNA by the ribosome requires a transition from an open to a closed formQ27640089
Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progressionQ27640330
Structural basis for the antibiotic activity of ketolides and azalidesQ27640646
Structural insight into the role of the ribosomal tunnel in cellular regulationQ27640852
Structural Insight into the Antibiotic Action of Telithromycin against Resistant MutantsQ27641602
The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistanceQ27766382
Ribosome structure and the mechanism of translationQ28209121
Mechanism of ribosomal peptide bond formation.Q32035641
Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expressionQ33787527
Signal sequence recognition and protein targetingQ33801827
Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunitQ33929419
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transitionQ33942967
Upstream open reading frames as regulators of mRNA translationQ33966388
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22.Q34087308
The ribosomal exit tunnel functions as a discriminating gateQ34118341
Ribosome fidelity: tRNA discrimination, proofreading and induced fit.Q34134651
Unusual resistance of peptidyl transferase to protein extraction proceduresQ34436822
Regulatory nascent peptides in the ribosomal tunnelQ34563139
The search and its outcome: high-resolution structures of ribosomal particles from mesophilic, thermophilic, and halophilic bacteria at various functional statesQ34623595
The involvement of RNA in ribosome functionQ34732208
Antibiotics targeting ribosomes: crystallographic studiesQ35014480
After the ribosome structures: how does peptidyl transferase work?Q35055506
The chemistry of protein synthesis and voyage through the ribosomal tunnelQ35119746
Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.Q35592133
Erythromycin resistance by ribosome modificationQ39779280
Ribosomes and translationQ41550248
Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocationQ41631336
Molecular movement inside the translational engineQ41708894
Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosomeQ41942083
Puromycin-rRNA interaction sites at the peptidyl transferase centerQ42170056
Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotideQ43617727
Intermediate states in the movement of transfer RNA in the ribosomeQ44026748
Instruction of translating ribosome by nascent peptideQ44135169
The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.Q44283112
Movement of tRNA but not the nascent peptide during peptide bond formation on ribosomesQ44394996
Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.Q54539576
Biochemical and kinetic characteristics of the interaction of the antitumor antibiotic sparsomycin with prokaryotic and eukaryotic ribosomesQ57977649
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNAQ58032510
On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes. Delivered on 20 October 2002 at the 28th FEBS Meeting in IstanbulQ60337687
A Sparsomycin-resistant Mutant ofHalobacterium salinariumLacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNAQ61862594
A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstructionQ69004129
The inactivation and reactivation of ribosomal-peptidyl transferase of E. coliQ69857173
Location of exit channel for nascent protein in 80S ribosomeQ70020849
Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translationQ71396621
Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integrationQ73526936
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
organic chemistryQ11351
molecular medicineQ3523816
P304page(s)1008-1017
P577publication date2003-10-01
2003-10-06
P1433published inChemBioChemQ634395
P1476titleStructural insight into functional aspects of ribosomal RNA targeting
Structural Insight Into Functional Aspects of Ribosomal RNA Targeting
P478volume4

Reverse relations

cites work (P2860)
Q34470492A chemoenzymatic route to diversify aminoglycosides enables a microarray-based method to probe acetyltransferase activity
Q45741815Crystal structure of the methyltransferase domain of human TARBP1.
Q36024306From peptide-bond formation to cotranslational folding: dynamic, regulatory and evolutionary aspects
Q22255611Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics
Q41975063Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.
Q37257100Studying modification of aminoglycoside antibiotics by resistance-causing enzymes via microarray
Q36257983Symmetry at the active site of the ribosome: structural and functional implications