The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias

scientific article published on 16 April 2013

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00280-013-2136-7
P932PMC publication ID4414393
P698PubMed publication ID23589314

P50authorKenneth C. AndersonQ28421846
Paul G. RichardsonQ87712102
Melissa OoiQ89531124
Jana JakubikovaQ89681431
Peter H GormanQ91117968
Martin ClynesQ92266724
Jake E DelmoreQ117224718
Constantine S MitsiadesQ117224720
Steffen KlippelQ117224723
P2093author name stringRobert O'Connor
Justine Meiller
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Expression of MDR1/P-glycoprotein, the multidrug resistance protein MRP, and the lung-resistance protein LRP in multiple myelomaQ44103318
A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group studyQ44158194
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applicationsQ44211035
Phase III study of PSC-833 (valspodar) in combination with vincristine, doxorubicin, and dexamethasone (valspodar/VAD) versus VAD alone in patients with recurring or refractory multiple myeloma (E1A95): a trial of the Eastern Cooperative Oncology GrQ46898523
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The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells.Q53530281
Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms and p53 status.Q53585037
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Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)Q58838535
Acid phosphatase: endpoint for in vitro toxicity testsQ70155179
Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa BQ70903372
Transforming growth factor-beta1: differential effects on multiple myeloma versus normal B cellsQ71087693
Characterization of marrow stromal (fibroblastoid) cells and their association with erythropoiesisQ71474840
Reversal of multidrug resistance by SDZ PSC 833, combined with VAD (vincristine, doxorubicin, dexamethasone) in refractory multiple myeloma. A phase I studyQ71727922
The human multidrug resistance P-glycoprotein is inactive when its maturation is inhibited: potential for a role in cancer chemotherapyQ73042152
Knockdown of PgP resensitizes leukemic cells to proteasome inhibitorsQ80699766
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1357-1368
P577publication date2013-04-16
P1433published inCancer Chemotherapy and PharmacologyQ326137
P1476titleThe interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias
P478volume71

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cites work (P2860)
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