Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal).

scientific article published on 15 November 2011

Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BPJ.2011.10.004
P932PMC publication ID3218331
P698PubMed publication ID22098739
P5875ResearchGate publication ID51813069

P2093author name stringI Martha Skerrett
Pauline Phelan
Adam Depriest
P2860cites workInterhelical hydrogen bonds and spatial motifs in membrane proteins: polar clamps and serine zippersQ43947468
Opening the KcsA K+ channel: tryptophan scanning and complementation analysis lead to mutants with altered gatingQ44212881
Structural and functional role of helices I and II in rhodopsin. A novel interplay evidenced by mutations at Gly-51 and Gly-89 in the transmembrane domainQ44378781
Tryptophan scanning mutagenesis in the alphaM3 transmembrane domain of the Torpedo californica acetylcholine receptor: functional and structural implicationsQ44624187
The shaking B gene in Drosophila regulates the number of gap junctions between photoreceptor terminals in the laminaQ47070919
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Tryptophan-scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation.Q50641169
Applying the Xenopus oocyte expression system to the analysis of gap junction proteins.Q50718434
Tryptophan-scanning mutagenesis of MotB, an integral membrane protein essential for flagellar rotation in Escherichia coli.Q54608355
Effects of Aromatic Residues at the Ends of Transmembrane α-Helices on Helix Interactions with Lipid Bilayers†Q57365142
Topology of the Mr 27,000 liver gap junction protein. Cytoplasmic localization of amino- and carboxyl termini and a hydrophilic domain which is protease-hypersensitiveQ69844454
Null mutation in shaking-B eliminates electrical, but not chemical, synapses in the Drosophila giant fiber system: a structural studyQ78166485
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Pannexin: to gap or not to gap, is that a question?Q28248565
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Three distinct structural environments of a transmembrane domain in the inwardly rectifying potassium channel ROMK1 defined by perturbationQ33643077
Gap junctions.Q34020827
Opening hemichannels in nonjunctional membrane stimulates gap junction formationQ34184768
SCAM analysis of Panx1 suggests a peculiar pore structureQ34243032
Innexins get into the gap.Q34243564
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Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanolQ35042675
Gap junction channel gatingQ35700096
Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibuleQ35830244
The lipid-protein interface of a Shaker K(+) channelQ35834786
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Tryptophan scanning of the acetylcholine receptor's betaM4 transmembrane domain: decoding allosteric linkage at the lipid-protein interface with ion-channel gatingQ36810393
Molecular mechanism of rectification at identified electrical synapses in the Drosophila giant fiber systemQ37146232
Site-directed mutagenesis reveals putative regions of protein interaction within the transmembrane domains of connexinsQ37169087
Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous systemQ37223556
Tryptophan scanning analysis of the membrane domain of CTR-copper transportersQ39879463
Gap junctions in Drosophila: developmental expression of the entire innexin gene familyQ40646001
Voltage gating of Cx43 gap junction channels involves fast and slow current transitionsQ40903511
Three-dimensional structure of a recombinant gap junction membrane channelQ40972332
Changes in permeability caused by connexin 32 mutations underlie X-linked Charcot-Marie-Tooth diseaseQ41082001
Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizationsQ41092749
Where are the gates in gap junction channels?Q41284659
The mechanism of rectification at the electrotonic motor giant synapse of the crayfishQ41472957
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closureQ41558471
Multiple conductance states of newly formed single gap junction channels between insect cellsQ41564565
Limitations of the dual voltage clamp method in assaying conductance and kinetics of gap junction channelsQ42583940
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecttransmembrane proteinQ424204
P304page(s)2408-2416
P577publication date2011-11-15
P1433published inBiophysical JournalQ2032955
P1476titleTryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal).
P478volume101

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cites work (P2860)
Q38942940A structural and functional comparison of gap junction channels composed of connexins and innexins
Q38650722Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions.
Q41599920Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.
Q38190298Control of neuronal morphology and connectivity: emerging developmental roles for gap junctional proteins
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Q43462143Gap junction-dependent homolog avoidance in the developing CNS.
Q58573389Innexins: Expression, Regulation, and Functions
Q39794957Oligomeric structure and functional characterization of Caenorhabditis elegans Innexin-6 gap junction protein
Q48611494Role of amino terminus in voltage gating and junctional rectification of Shaking B innexins
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Q90253180The Transmembrane Domain of Synaptobrevin Influences Neurotransmitter Flux through Synaptic Fusion Pores
Q27027940The pannexins: past and present
Q35837081Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32

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