Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice

scientific article published on 20 June 2011

Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1003196064
P356DOI10.1186/AR3372
P932PMC publication ID3218912
P698PubMed publication ID21689431
P5875ResearchGate publication ID51234787

P50authorStefan SchulzQ42289701
P2093author name stringMieczyslaw Gajda
Rolf Bräuer
Hans-Georg Schaible
Laura Glück
Anne-Katja Imhof
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Endothelin antagonism prevents diabetic retinopathy in NOD mice: a potential role of the angiogenic factor adrenomedullin.Q33245457
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IL-33 mediates antigen-induced cutaneous and articular hypernociception in miceQ36497523
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Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal targetQ39316366
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Inhibitory effects of a selective endothelin-A receptor antagonist YM598 on endothelin-1-induced potentiation of nociception in formalin-induced and prostate cancer-induced pain models in miceQ40433475
Loss of phosphoinositide 3-kinase gamma decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritisQ40482523
Elevated plasma endothelin-1 levels and vascular dysregulation in patients with rheumatoid arthritis.Q40635299
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Nociceptive reaction and thermal hyperalgesia induced by local ET-1 in mice: a behavioral and Fos studyQ44343063
Gait abnormalities differentially indicate pain or structural joint damage in monoarticular antigen-induced arthritisQ44637500
Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive mannerQ44838317
Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in miceQ46316804
The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathyQ46920842
Endothelin 1 activates and sensitizes human C-nociceptorsQ46989861
Roles of endothelin ETA and ETB receptors in nociception and chemical, thermal and mechanical hyperalgesia induced by endothelin-1 in the rat hindpaw.Q47841942
Endothelin-1 (ET-1) selectively enhances the activation gating of slowly inactivating tetrodotoxin-resistant sodium currents in rat sensory neurons: a mechanism for the pain-inducing actions of ET-1.Q49072411
Antigen-induced arthritis in mice. I. Induction of arthritis in various strains of mice.Q54598631
Endothelin B receptor modulates inflammatory pain and cutaneous inflammationQ73018863
Serum and synovial fluid concentrations of endothelin-1 in patients with rheumatoid arthritisQ73068539
Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociceptionQ73395789
Endothelin-1 production by human synoviocytesQ74455545
Endothelin ETB receptors inhibit articular nociception and priming induced by carrageenan in the rat knee-jointQ80406832
A role for endothelin in neuropathic pain after chronic constriction injury of the sciatic nerveQ81511338
Endothelin ET(B) receptor antagonist reduces mechanical allodynia in rats with trigeminal neuropathic painQ83896086
Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletionQ84823764
P433issue3
P304page(s)R97
P577publication date2011-06-20
P1433published inArthritis Research and TherapyQ15757229
P1476titlePotent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice
P478volume13

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Q42500618Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes
Q93164801Chloride - The Underrated Ion in Nociceptors
Q46777140Effect of gedunin on acute articular inflammation and hypernociception in mice
Q34140692Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain
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