Phase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer

scientific article published on 28 October 2008

Phase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10637-008-9194-4
P932PMC publication ID3219507
P698PubMed publication ID18956138
P5875ResearchGate publication ID23423904

P2093author name stringGary Schwartz
Deborah Schrag
Leonard B Saltz
David H Ilson
William P Tew
David P Kelsen
Eileen O'Reilly
Delia Radovich
Stacey Kepler
P2860cites workCancer statistics, 2008Q27860585
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of CanadaQ27860904
A weekly regimen of cisplatin, paclitaxel and topotecan with granulocyte-colony stimulating factor support for patients with extensive disease small cell lung cancer: a phase II studyQ28364196
Phase I trial of the combination of irinotecan, paclitaxel, and carboplatin in patients with advanced non-small-cell lung cancerQ31960280
Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancerQ33328101
Cisplatin-topotecan-paclitaxel weekly administration with G-CSF support for ovarian and small-cell lung cancer patients: a dose-finding study.Q33329062
Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) With epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancerQ33341957
Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancerQ33371032
Paclitaxel given by a weekly 1-h infusion in advanced esophageal cancerQ33374495
Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancerQ33498653
Phase I dose escalation of paclitaxel in patients with advanced ovarian cancer receiving cisplatin: rapid development of neurotoxicity is dose-limitingQ33499374
Chemotherapy with cisplatin and paclitaxel in patients with locally advanced, recurrent or metastatic oesophageal cancerQ33503431
Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: a multicenter, retrospective analysisQ34550816
Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study GroupQ34572233
Treatment of metastatic esophagus and gastric cancerQ35857455
Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancerQ39436075
Phase II study of a combination of irinotecan and cisplatin against metastatic gastric cancerQ40800385
Sequence-dependent modulation of anticancer drug activities by 7-ethyl-10-hydroxycamptothecin in an HST-1 human squamous carcinoma cell lineQ41364890
Effects of CPT-11 in combination with other anti-cancer agents in cultureQ41639325
Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancerQ43850218
Irinotecan/cisplatin in advanced, treated gastric or gastroesophageal junction carcinoma.Q44057365
Phase II trial of irinotecan, paclitaxel and carboplatin in patients with previously untreated Stage IIIB/IV nonsmall cell lung carcinomaQ44141804
Phase I trial of escalating-dose irinotecan given weekly with cisplatin and concurrent radiotherapy in locally advanced esophageal cancerQ44529248
Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junctionQ44908374
CPT-11 plus cisplatin in patients with advanced, untreated gastric or gastroesophageal junction carcinoma: results of a phase II studyQ45714364
Esophageal CancerQ56209683
Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: an active regimen with limiting neurotoxicityQ57610374
Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cellsQ71079802
Activity of taxol in patients with squamous cell carcinoma and adenocarcinoma of the esophagusQ72683495
Bolus and infusional 5-fluorouracil combined with cisplatin in advanced gastric cancerQ73081208
A phase II trial of paclitaxel and cisplatin in patients with advanced carcinoma of the esophagusQ73192094
Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancerQ73707393
Phase I clinical and pharmacologic study of weekly cisplatin combined with weekly irinotecan in patients with advanced solid tumorsQ77669925
P433issue4
P921main subjectphase I clinical trialQ5452194
irinotecanQ412197
paclitaxelQ423762
P304page(s)366-373
P577publication date2008-10-28
P1433published inInvestigational New DrugsQ2312231
P1476titlePhase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer
P478volume27

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