| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1029085738 |
| P356 | DOI | 10.1186/CC9342 |
| P932 | PMC publication ID | 3220026 |
| P698 | PubMed publication ID | 21110850 |
| P5875 | ResearchGate publication ID | 49638753 |
| P50 | author | Eszter Maria Horvath | Q57017403 |
| P2093 | author name string | John F Fraser | |
| David N Herndon | |||
| Csaba Szabo | |||
| Daniel L Traber | |||
| Lillian D Traber | |||
| Yoshimitsu Nakano | |||
| Levente Kiss | |||
| Martin Westphal | |||
| Dirk M Maybauer | |||
| Marc O Maybauer | |||
| P2860 | cites work | The ACCP-SCCM consensus conference on sepsis and organ failure. | Q55041019 |
| Effect of severe smoke inhalation injury on systemic microvascular blood flow in sheep | Q71713083 | ||
| Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia | Q73400630 | ||
| Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis | Q79817078 | ||
| Recombinant human activated protein C in experimental models of acute lung injury: the timing is critical! | Q80727321 | ||
| Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care | Q27860820 | ||
| Efficacy and safety of recombinant human activated protein C for severe sepsis | Q29547839 | ||
| Hemodynamic, metabolic, and organ function effects of pure oxygen ventilation during established fecal peritonitis-induced septic shock. | Q33468834 | ||
| Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier | Q33954036 | ||
| Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death | Q34455153 | ||
| Endogenous protein C activation in patients with severe sepsis | Q35760617 | ||
| Nitric oxide synthase inhibition in sepsis? Lessons learned from large-animal studies | Q36203883 | ||
| Catecholamines and vasopressin during critical illness | Q36362920 | ||
| Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease | Q36734840 | ||
| Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity | Q37066127 | ||
| Recombinant human activated protein C in acute lung injury: what is the role of bronchial circulation? | Q37396057 | ||
| Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial. | Q40235280 | ||
| Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep | Q40278296 | ||
| Activated protein C can be used as a prophylactic as well as a therapeutic agent for heat stroke in rodents | Q40394496 | ||
| Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep | Q41853033 | ||
| Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep | Q42673776 | ||
| Distinct functions of activated protein C differentially attenuate acute kidney injury. | Q43186023 | ||
| Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep. | Q43249056 | ||
| Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide | Q43727878 | ||
| Modification of alpha1 -adrenoceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis | Q43952551 | ||
| A novel animal model of sepsis after acute lung injury in sheep | Q44091880 | ||
| Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines | Q44232110 | ||
| Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep | Q44355165 | ||
| Deactivation of norepinephrine by peroxynitrite as a new pathogenesis in the hypotension of septic shock | Q44376743 | ||
| Expression and function of the endothelial protein C receptor in human neutrophils | Q44417143 | ||
| Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model | Q45256622 | ||
| Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress | Q46643306 | ||
| Rapid and beneficial hemodynamic effects of activated protein C in septic shock patients. | Q46713862 | ||
| Effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis | Q46842542 | ||
| Beneficial effects of recombinant human activated protein C in a ewe model of septic shock | Q46977001 | ||
| Inhibition of coagulation and inflammation by activated protein C or antithrombin reduces intestinal ischemia/reperfusion injury in rats | Q47369794 | ||
| Microhemodynamic and cellular mechanisms of activated protein C action during endotoxemia | Q47797708 | ||
| Effects of drotrecogin alfa (activated) in human endotoxemia | Q48021028 | ||
| Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model | Q48315526 | ||
| Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock. | Q51753265 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sepsis | Q183134 |
| drotrecogin alfa | Q412888 | ||
| septic shock | Q1765564 | ||
| acute lung injury | Q4677935 | ||
| P304 | page(s) | R217 | |
| P577 | publication date | 2010-11-26 | |
| P1433 | published in | Critical Care | Q5186602 |
| P1476 | title | Recombinant human activated protein C attenuates cardiovascular and microcirculatory dysfunction in acute lung injury and septic shock | |
| P478 | volume | 14 |
| Q54567152 | Comparative effects of recombinant human activated protein C and dexamethasone in experimental septic shock. |
| Q30547629 | Intracardiac echocardiography guided transeptal catheter injection of microspheres for assessment of cerebral microcirculation in experimental models |
| Q38021265 | Microparticles and acute lung injury |
| Q30811829 | Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care |
| Q34999953 | The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome |
| Q35112641 | The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock |
| Q37966024 | Year in review 2010: Critical Care--Cardiology |
| Q26823098 | Year in review 2010: Critical Care--Multiple organ dysfunction and sepsis |
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