The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids

scientific article published on 17 February 2015

The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKV056
P932PMC publication ID4417144
P698PubMed publication ID25690889
P5875ResearchGate publication ID272513508

P50authorPatrick BastienQ63635696
Nada KukQ66829215
Yvon SterkersQ66829216
Lucien CrobuQ115607870
P2093author name stringLaurence Lachaud
Christelle Morelle
Pierre Portalès
Michel Pagès
Diane-Ethna MBang-Benet
P2860cites workThe genome of the kinetoplastid parasite, Leishmania majorQ22065797
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.Q24298502
A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assemblyQ24300687
Proteomic analysis of the mammalian nuclear pore complexQ24305242
Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusionQ24307496
Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpointQ24311706
Spatiotemporal control of mitosis by the conserved spindle matrix protein MegatorQ24319051
The nuclear pore complexQ24542535
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalphaQ24648999
Improved tools for biological sequence comparisonQ24652199
Nup358 integrates nuclear envelope breakdown with kinetochore assemblyQ24675421
Rae1 interaction with NuMA is required for bipolar spindle formationQ24676429
The nuclear pore complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assemblyQ24679287
The yeast nuclear pore complex: composition, architecture, and transport mechanismQ24680784
Gene recruitment of the activated INO1 locus to the nuclear membraneQ24794933
Basic local alignment search toolQ25938991
Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genomeQ27348460
Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.Q27646584
Predicting coiled coils from protein sequencesQ27861097
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA exportQ27936733
Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complexQ27937326
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelopeQ27937982
Interaction of a DNA Zip Code with the Nuclear Pore Complex Promotes H2A.Z Incorporation and INO1 Transcriptional MemoryQ27938380
Genetic network interactions among replication, repair and nuclear pore deficiencies in yeastQ27939246
Nuclear pore complexes in the organization of silent telomeric chromatinQ27939276
The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpointQ27939354
Nucleocytoplasmic transportQ28275907
Centromere-associated topoisomerase activity in bloodstream form Trypanosoma bruceiQ28743001
The nuclear pore complex and nuclear transportQ28749193
Nucleocytoplasmic transport: signals, mechanisms and regulationQ29547904
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma bruceiQ29617358
Mlp1 acts as a mitotic scaffold to spatially regulate spindle assembly checkpoint proteins in Aspergillus nidulansQ30487023
Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activityQ30577298
Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma bruceiQ31030771
Functional interaction between the Arabidopsis orthologs of spindle assembly checkpoint proteins MAD1 and MAD2 and the nucleoporin NUA.Q33353266
Gatekeepers of the nucleusQ33927537
The nuclear pore complex: bridging nuclear transport and gene regulationQ34122297
Centromere-associated repeat arrays on Trypanosoma brucei chromosomes are much more extensive than predictedQ34132489
Nuclear pores and nuclear assemblyQ34245411
The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulationsQ34463101
The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1.Q34558155
Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genesQ35131387
RNA interference in protozoan parasites: achievements and challengesQ35271326
Morphological events during the cell cycle of Leishmania major.Q35530328
The nucleoporin Nup358 associates with and regulates interphase microtubulesQ36499514
Amplification of the inosinate dehydrogenase gene in Trypanosoma brucei gambiense due to an increase in chromosome copy number.Q36726994
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.Q36808794
Cohesin subunit SMC1 associates with mitotic microtubules at the spindle poleQ36917033
Cell and molecular biology of the spindle matrixQ36921745
Post-transcriptional regulation of gene expression in trypanosomes and leishmaniasQ36927117
The role of nuclear pores in gene regulation, development and diseaseQ37306669
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestorQ37343080
Megator, an essential coiled-coil protein that localizes to the putative spindle matrix during mitosis in Drosophila.Q37594854
Double duty for nuclear proteins--the price of more open forms of mitosisQ37625057
Discovery of unconventional kinetochores in kinetoplastids.Q37690124
An update on cohesin function as a 'molecular glue' on chromosomes and spindlesQ37740917
Control of eukaryotic gene expression: gene loops and transcriptional memory.Q37805178
Nucleoporins: leaving the nuclear pore complex for a successful mitosisQ37891213
Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.Q38031615
Nuclear pore complex composition: a new regulator of tissue-specific and developmental functionsQ38054510
Exotic mitotic mechanismsQ38070151
Nuclear pore complexes in the maintenance of genome integrity.Q38097224
SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC.Q40045995
Molecular dissection of the nuclear pore complexQ41063786
Characterization of the role of the tumor marker Nup88 in mitosisQ41348416
A physiological role for gene loops in yeast.Q42116820
Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma bruceiQ42510854
Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethalityQ42916271
Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiaeQ42949353
NUA Activities at the Plant Nuclear PoreQ43189486
Trisomy and chromosome size changes in hybrid trypanosomes from a genetic cross between Trypanosoma brucei rhodesiense and T. b. bruceiQ47414676
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparumQ47873714
THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association.Q50336097
Cell cycle-dependent expression regulation by the proteasome pathway and characterization of the nuclear targeting signal of a Leishmania major Kin-13 kinesin.Q50741762
Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control.Q52548665
A vector series for rapid PCR-mediated C-terminal in situ tagging of Trypanosoma brucei genes.Q54632650
Chromosome fragmentation in leishmania.Q54716802
Nuclear pore association confers optimal expression levels for an inducible yeast geneQ59054249
The nuclear pore complexQ71778522
Partitioning of large and minichromosomes in Trypanosoma bruceiQ73248175
Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complexQ79421818
Functional characterization of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes in Trypanosoma bruceiQ83272779
FISH analysis reveals aneuploidy and continual generation of chromosomal mosaicism in Leishmania majorQ85235916
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectTrypanosomatidaeQ132954
P1104number of pages15
P304page(s)4013-4027
P577publication date2015-02-17
P1433published inNucleic Acids ResearchQ135122
P1476titleThe nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids
P478volume43

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cites work (P2860)
Q26779126Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint
Q39539881Constitutive aneuploidy and genomic instability in the single-celled eukaryote Giardia intestinalis
Q61485558Faithful chromosome segregation in Trypanosoma brucei requires a cohort of divergent spindle-associated proteins with distinct functions
Q48312853Identification of the centromeres of Leishmania major: revealing the hidden pieces.
Q52648051Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei.
Q36686405Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells

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