Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes

scientific article published on 3 October 2011

Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.257923
P8608Fatcat IDrelease_eblsz23ozrb2tf2ih2bfglwqkm
P932PMC publication ID3220500
P698PubMed publication ID21969372
P5875ResearchGate publication ID51691036

P50authorBradlee L HeckmannQ57040530
P2093author name stringXin Lu
Jun Liu
Xiaodong Zhang
Xingyuan Yang
P2860cites workIsoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytesQ42812532
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Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytesQ42826561
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytesQ42826631
Stimulation of lipolysis by tumor necrosis factor-alpha in 3T3-L1 adipocytes is glucose dependent: implications for long-term regulation of lipolysisQ42832922
Short-term regulation of tumor necrosis factor-alpha-induced lipolysis in 3T3-L1 adipocytes is mediated through the inducible nitric oxide synthase/nitric oxide-dependent pathwayQ42833088
Tumor necrosis factor-alpha modulates human in vivo lipolysisQ43590617
Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP.Q44155489
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ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liverQ50336015
HORMONE-SENSITIVE LIPASE AND MONOGLYCERIDE LIPASE ACTIVITIES IN ADIPOSE TISSUEQ55037557
The multifunctional role of hormone-sensitive lipase in lipid metabolismQ72759164
Tumor necrosis factor alpha stimulates lipolysis in adipocytes by decreasing Gi protein concentrationsQ74485215
ACTIVATION OF AN EPINEPHRINE-SENSITIVE LIPOLYTIC ACTIVITY FROM ADIPOSE TISSUE BY ADENOSINE 3',5'-PHOSPHATEQ76853137
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activitiesQ24303914
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman SyndromeQ24329220
Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysisQ28205459
cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidasesQ28252158
Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1cQ28505291
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testisQ28506864
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolismQ28512146
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha functionQ29616104
Lipid homeostasis, lipotoxicity and the metabolic syndrome.Q30383031
TXNIP regulates peripheral glucose metabolism in humansQ33283341
Regulation of lipolysis in adipocytesQ33913668
Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.Q34344442
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipaseQ34369246
The G0/G1 switch gene 2 is a novel PPAR target gene.Q34441198
Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytesQ34503345
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipaseQ34522091
Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat storesQ34543395
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesityQ34977813
TNF-alpha and adipocyte biologyQ35006572
Dysfunctional fat cells, lipotoxicity and type 2 diabetesQ36202576
Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activationQ36323578
The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipaseQ36858543
Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesityQ37141748
Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage dropletQ37198922
Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl).Q37454139
Lipolysis and lipid mobilization in human adipose tissueQ37493107
TNF-alpha, a potent lipid metabolism regulatorQ37598164
Adipose tissue lipolysisQ37763466
Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytesQ40206456
Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptorsQ40894968
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipaseQ41462901
Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytesQ42049407
Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMPQ42158524
Protein targeting to glycogen overexpression results in the specific enhancement of glycogen storage in 3T3-L1 adipocytesQ42442963
Metformin reduces lipolysis in primary rat adipocytes stimulated by tumor necrosis factor-alpha or isoproterenolQ42499584
The adipose tissue phenotype of hormone-sensitive lipase deficiency in miceQ42503258
Analysis of lipolytic protein trafficking and interactions in adipocytesQ42506067
Salicylate blocks lipolytic actions of tumor necrosis factor-alpha in primary rat adipocytesQ42519657
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytesQ42798527
P433issue47
P407language of work or nameEnglishQ1860
P921main subjecttriglycerideQ186319
adipocyteQ357519
P304page(s)40477-40485
P577publication date2011-10-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleRelative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes
P478volume286

Reverse relations

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