Apoptosis: target for novel drugs

scientific article published on November 1, 2003

Apoptosis: target for novel drugs is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.TIBTECH.2003.08.006
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0167779903002324?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0167779903002324?httpAccept=text/plain
P698PubMed publication ID14573360
P5875ResearchGate publication ID9043054

P2093author name stringJohn J. Alam
P2860cites workErythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injuryQ24530090
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivityQ27625099
Mechanisms of caspase activation and inhibition during apoptosisQ27919623
Proliferation, cell cycle and apoptosis in cancerQ28189476
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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemiaQ34183674
Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivationQ34381861
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Erythropoietin crosses the blood-brain barrier to protect against experimental brain injuryQ37250532
A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injuryQ40687709
Differential requirement for caspase 9 in apoptotic pathways in vivo.Q41015558
Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosisQ43559207
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Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct sizeQ43772704
Therapeutic strategies targeting caspase inhibition following spinal cord injury in ratsQ44214588
The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injuryQ44347302
Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyteQ45018156
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Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitorQ57424632
Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failureQ58314378
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activationQ70607132
In vivo detection of cell death in the area at risk in acute myocardial infarctionQ73088051
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitisQ73700066
Expression of Fas (CD95) and Fas ligand on peripheral blood mononuclear cells in critical illness and association with multiorgan dysfunction severity and survivalQ73928271
Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injuryQ74154142
Visualisation of cell death in vivo in patients with acute myocardial infarctionQ74236895
Soluble Fas and soluble Fas ligand levels in patients with acute hepatic failureQ74300335
The variable morphological coexistence of apoptosis and necrosis in human myocardial infarction: significance for understanding its pathogenesis, clinical course, diagnosis and prognosisQ77117126
Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injuryQ78060140
Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivoQ78202589
Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcomeQ78602259
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectbiotechnologyQ7108
bioengineeringQ580689
P304page(s)479-483
P577publication date2003-11-01
P1433published inTrends in BiotechnologyQ2451465
P1476titleApoptosis: target for novel drugs
P478volume21