| scholarly article | Q13442814 |
| P50 | author | Ramon Trullas | Q43157030 |
| P2093 | author name string | J A García-Sevilla | |
| A Villarroel | |||
| G Olmos | |||
| J Lerma | |||
| M Assumpció Boronat | |||
| M Paz Regalado | |||
| N DeGregorio-Rocasolano | |||
| T Gasull | |||
| P2860 | cites work | Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Q25939005 |
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| Agmatine: an endogenous clonidine-displacing substance in the brain | Q34321973 | ||
| Antazoline increases insulin secretion and improves glucose tolerance in rats and dogs | Q73328427 | ||
| Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block | Q77299364 | ||
| Inhibition of monoamine oxidase A and B activities by imidazol(ine)/guanidine drugs, nature of the interaction and distinction from I2-imidazoline receptors in rat liver | Q35026368 | ||
| Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands. | Q35027984 | ||
| The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain | Q35754743 | ||
| Imidazoline antagonists of alpha 2-adrenoceptors increase insulin release in vitro by inhibiting ATP-sensitive K+ channels in pancreatic beta-cells | Q35870817 | ||
| Ionic Blockage of Sodium Channels in Nerve | Q36388606 | ||
| Phentolamine block of KATP channels is mediated by Kir6.2. | Q36612957 | ||
| Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. | Q36684306 | ||
| Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate | Q37690554 | ||
| Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission | Q37893514 | ||
| Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage | Q38201300 | ||
| Excitatory amino acid-induced alterations of cytoplasmic free Ca2+ in individual cerebellar granule neurons: role in neurotoxicity | Q39243523 | ||
| Imidazoline receptors: from basic concepts to recent developments. | Q40994286 | ||
| Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system | Q41042568 | ||
| Imidazoline receptors and their endogenous ligands | Q41048237 | ||
| Imidazoli(di)ne compounds interact with the phencyclidine site of NMDA receptors in the rat brain. | Q41173402 | ||
| Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: pharmacological characterization | Q41277657 | ||
| Clonidine and cirazoline inhibit activation of nicotinic channels in PC-12 cells. | Q41326176 | ||
| Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors. | Q41446109 | ||
| Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release | Q42031092 | ||
| Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition. | Q42524694 | ||
| Modulation of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist LY274614: assessment of opioid receptor changes | Q44339475 | ||
| Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. | Q46875721 | ||
| Protection by imidazol(ine) compounds of L-glutamate neurotoxicity through NMDA receptor blockade | Q48155037 | ||
| Glutamate-induced neuronal death is not a programmed cell death in cerebellar culture | Q48298893 | ||
| Agmatine selectively blocks the N-methyl-D-aspartate subclass of glutamate receptor channels in rat hippocampal neurons | Q48299866 | ||
| Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures | Q48331531 | ||
| Effects of imidazole compounds on catecholamine release in adrenal chromaffin cells | Q48477673 | ||
| Glycine-independent NMDA receptor desensitization: localization of structural determinants | Q48517849 | ||
| Reduction in focal cerebral ischemia by agents acting at imidazole receptors | Q48595407 | ||
| Overexpression of glyceraldehyde-3-phosphate dehydrogenase is involved in low K+-induced apoptosis but not necrosis of cultured cerebellar granule cells | Q48746919 | ||
| Interaction of Mg2+ and phencyclidine in use-dependent block of NMDA channels | Q48793354 | ||
| Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action | Q48874352 | ||
| Structure-activity relationships of philanthotoxin analogs and polyamines on N-methyl-D-aspartate and nicotinic acetylcholine receptors | Q48909758 | ||
| Inhibition by imidazoline and imidazolidine derivatives of glibenclamide-sensitive K+ currents in Xenopus oocytes. | Q49096839 | ||
| Activation of voltage-dependent sodium channels in cultured cerebellar poffule cells induces neurotoxicity that is not mediated by glutamate release. | Q51567902 | ||
| Characterization of [3H]MK-801 binding to N-methyl-D-aspartate receptors in cultured rat cerebellar granule neurons and involvement in glutamate-mediated toxicity. | Q51580523 | ||
| Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801 | Q52052445 | ||
| Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane | Q67912100 | ||
| Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain | Q69367877 | ||
| Agmatine treatment is neuroprotective in rodent brain injury models | Q71013698 | ||
| Inhibition of 5-HT3 receptor function by imidazolines in mouse neuroblastoma cells: potential involvement of sigma 2 binding sites | Q71699805 | ||
| Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites | Q71793208 | ||
| Effects of alpha 2-adrenoceptor antagonists and imidazoline2-receptor ligands on neuronal damage in global ischaemia in the rat | Q73166778 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neurotoxicity | Q3338704 |
| toxic encephalopathy | Q7830379 | ||
| P304 | page(s) | 1317-1326 | |
| P577 | publication date | 1999-07-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor | |
| P478 | volume | 127 |
| Q73276365 | Accelerated functional recovery and neuroprotection by agmatine after spinal cord ischemia in rats |
| Q34700010 | Agmatine : metabolic pathway and spectrum of activity in brain |
| Q35778616 | Agmatine Attenuates Brain Edema and Apoptotic Cell Death after Traumatic Brain Injury |
| Q38837164 | Agmatine Protects Against 6-OHDA-Induced Apoptosis, and ERK and Akt/GSK Disruption in SH-SY5Y Cells |
| Q42414712 | Agmatine attenuates brain edema through reducing the expression of aquaporin-1 after cerebral ischemia |
| Q46671560 | Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model |
| Q24635197 | Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y |
| Q38969497 | Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line |
| Q44388429 | Agmatine induces anxiolysis in the elevated plus maze task in adult rats |
| Q44624829 | Agmatine induces glutamate release and cell death in cultured rat cerebellar granule neurons |
| Q40891175 | Agmatine protects Müller cells from high-concentration glucose-induced cell damage via N-methyl-D-aspartic acid receptor inhibition |
| Q42259205 | Agmatine protects against cell damage induced by NMDA and glutamate in cultured hippocampal neurons. |
| Q34177685 | Agmatine protects against zymosan-induced acute lung injury in mice by inhibiting NF-κB-mediated inflammatory response |
| Q36102999 | Agmatine reduces balance deficits in a rat model of third trimester binge-like ethanol exposure |
| Q34061709 | Agmatine reduces extracellular glutamate during pentylenetetrazole-induced seizures in rat brain: a potential mechanism for the anticonvulsive effects |
| Q44161304 | Agmatine suppresses nitric oxide production and attenuates hypoxic-ischemic brain injury in neonatal rats |
| Q46749593 | Agmatine treatment and vein graft reconstruction enhance recovery after experimental facial nerve injury |
| Q38875865 | Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice |
| Q36616315 | Agmatine: biological role and therapeutic potentials in morphine analgesia and dependence |
| Q43244743 | Anti-apoptotic effect of memantine against staurosporine- and low-potassium-induced cell death in cerebellar granule cells: a development-dependent effect |
| Q37310452 | Antineoplastic activity of idazoxan hydrochloride |
| Q34199042 | Arginine metabolism and the synthesis of nitric oxide in the nervous system |
| Q33684041 | Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia |
| Q24673628 | Biological significance of agmatine, an endogenous ligand at imidazoline binding sites |
| Q44381639 | CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons. |
| Q33186744 | Calcium-activated NO production plays a role in neuronal death induced by β-bungarotoxin in primary cultures of cerebellar granular neurons |
| Q46816573 | Central actions of agmatine in conscious spontaneously hypertensive rats |
| Q45851009 | Chronic treatment with selective I2-imidazoline receptor ligands decreases the content of pro-apoptotic markers in rat brain |
| Q47663697 | Decreased plasma agmatine levels in autistic subjects |
| Q47628111 | Dynamics of arginase gene evolution in metazoans |
| Q37692352 | Effects of opioids, cannabinoids, and vanilloids on body temperature |
| Q47141323 | Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia |
| Q44895991 | I1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells. |
| Q39189902 | Imidazoline I2 receptors: An update |
| Q43055558 | Imidazoline binding sites on receptors and enzymes: emerging targets for novel antidepressant drugs? |
| Q33183424 | Imidazoline drugs stabilize lysosomes and inhibit oxidative cytotoxicity in astrocytes |
| Q74271930 | Imidazoline-induced neuroprotective effects result from blockade of NMDA receptor channels in neuronal cultures |
| Q48147582 | Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: Effects of treatments with I1- and I2-imidazoline drugs. |
| Q41906787 | Induction of reactive astrocytosis and prevention of motoneuron cell death by the I(2)-imidazoline receptor ligand LSL 60101. |
| Q46011245 | Influence of agmatine on the protective action of numerous antiepileptic drugs against pentetrazole-induced seizures in mice. |
| Q48676945 | Inhibitory effects of imidazoline receptor ligands on basal and kainic acid-induced neurotoxic signalling in mice |
| Q44883769 | Interaction between clonidine and N-methyl-D-aspartate receptors in the caudal ventrolateral medulla of rats |
| Q46897079 | Investigation of antioxidant vitamins (A, E, C) and lipid peroxidation levels in rats injected N-(1,3-benzothiazol-2-yl)-N-(4,5-dihydro-1H-imidazol-2-yl) amine |
| Q33901031 | Is agmatine a novel neurotransmitter in brain? |
| Q47383816 | Modulation of the anticonvulsant effect of swim stress by agmatine |
| Q46723175 | Neurochemical evidence for agmatine modulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity |
| Q44532210 | Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus |
| Q34067220 | Neuroprotective effects of agmatine against cell damage caused by glucocorticoids in cultured rat hippocampal neurons |
| Q37709458 | Nitric Oxide Synthase Inhibitors as Antidepressants |
| Q95643364 | Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators |
| Q43796419 | Opposite effects of low and high doses of arginine on glutamate-induced nitric oxide formation in rat substantia nigra |
| Q73076723 | Overexpression of neuronal pentraxin 1 is involved in neuronal death evoked by low K(+) in cerebellar granule cells |
| Q51060602 | Participation of central imidazoline binding sites in antinociceptive effect of ethanol and nicotine in rats. |
| Q43239576 | Protection in glutamate-induced neurotoxicity by imidazoline receptor agonist moxonidine |
| Q44207276 | Protective effects of rilmenidine and AGN 192403 on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes |
| Q34144557 | RX 821002 as a tool for physiological investigation of alpha(2)-adrenoceptors. |
| Q44167746 | Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil |
| Q38482437 | Recombinant hexahistidine arginine decarboxylase (hisADC) induced endogenous agmatine synthesis during stress |
| Q37500315 | The Effect of Agmatine on Expression of IL-1β and TLX Which Promotes Neuronal Differentiation in Lipopolysaccharide-Treated Neural Progenitors |
| Q48158658 | The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain? |