review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1089/152308603770310211 |
P953 | full work available at URL | http://www.liebertpub.com/doi/pdf/10.1089/152308603770310211 |
P698 | PubMed publication ID | 14580311 |
P50 | author | Hiroshi Masutani | Q84876314 |
P2093 | author name string | Junji Yodoi | |
Hajime Nakamura | |||
Toru Yoshida | |||
Shin-ichi Oka | |||
P2860 | cites work | Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells | Q24298232 |
Mutation of the mouse klotho gene leads to a syndrome resembling ageing | Q24328782 | ||
High-quality life extension by the enzyme peptide methionine sulfoxide reductase | Q24530884 | ||
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. | Q24533236 | ||
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin. | Q24535620 | ||
Aging and resistance to oxidative damage in Caenorhabditis elegans | Q24561446 | ||
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms | Q24597989 | ||
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse) | Q24654776 | ||
Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation | Q35451653 | ||
Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan | Q35892899 | ||
Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage | Q36459878 | ||
Expression of a vitamin D-regulated gene (VDUP-1) in untreated- and MNU-treated rat mammary tissue | Q41051533 | ||
Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans | Q43559952 | ||
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans | Q43799857 | ||
Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin | Q45906743 | ||
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes | Q47068796 | ||
Determination of life-span in Caenorhabditis elegans by four clock genes | Q47068808 | ||
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons | Q47991847 | ||
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. | Q48486981 | ||
A progeroid syndrome in mice is caused by defects in A-type lamins | Q52105480 | ||
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. | Q52543010 | ||
Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2. | Q53967999 | ||
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. | Q54084101 | ||
Dwarf mice and the ageing process. | Q55066759 | ||
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing | Q59086518 | ||
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging | Q63951809 | ||
Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha | Q77754258 | ||
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase | Q27860668 | ||
Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression | Q28140461 | ||
Deletion of Ku86 causes early onset of senescence in mice | Q28144342 | ||
Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat | Q28203333 | ||
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein | Q28211215 | ||
Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3 | Q28248159 | ||
Mutations in the WRN gene in mice accelerate mortality in a p53-null background | Q28510148 | ||
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production | Q28511652 | ||
Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process | Q28564586 | ||
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals | Q28587714 | ||
Premature aging in mice deficient in DNA repair and transcription | Q28593981 | ||
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans | Q28611331 | ||
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans | Q28611332 | ||
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system | Q28771747 | ||
Effects of development and ageing on pulmonary NADPH-cytochrome c reductase, glutathione peroxidase, glutathione reductase and thioredoxin reductase activities in male and female rats | Q29347069 | ||
Extended longevity in mice lacking the insulin receptor in adipose tissue | Q29614549 | ||
The p66shc adaptor protein controls oxidative stress response and life span in mammals | Q29614553 | ||
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice | Q29616382 | ||
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function | Q29618026 | ||
Positional cloning of the Werner's syndrome gene | Q29618393 | ||
Thioredoxin | Q29619691 | ||
p53 mutant mice that display early ageing-associated phenotypes | Q29622826 | ||
Induction of senescence-associated genes by 5-bromodeoxyuridine in HeLa cells. | Q30983475 | ||
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. | Q33786987 | ||
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres | Q33890968 | ||
Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma | Q33942829 | ||
Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis | Q34086331 | ||
Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death | Q34134849 | ||
Redox regulation of cellular activation | Q34425412 | ||
Rapid accumulation of genome rearrangements in liver but not in brain of old mice | Q34449310 | ||
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice | Q34463545 | ||
Extended life-span and stress resistance in the Drosophila mutant methuselah | Q34477849 | ||
Epstein-Barr virus-containing B-cell line produces an interleukin 1 that it uses as a growth factor | Q34593556 | ||
Oxidative stress and life span determination in the nematode Caenorhabditis elegans | Q34614576 | ||
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. | Q34763602 | ||
Redox control of cell death | Q34820717 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | physiology | Q521 |
biochemistry | Q7094 | ||
cell biology | Q7141 | ||
P304 | page(s) | 563-570 | |
P577 | publication date | 2003-10-01 | |
P1433 | published in | Antioxidants & Redox Signaling | Q4775078 |
P1476 | title | The role of thioredoxin in the aging process: involvement of oxidative stress | |
The Role of Thioredoxin in the Aging Process: Involvement of Oxidative Stress | |||
P478 | volume | 5 |
Q33321232 | A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway |
Q38518171 | Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro |
Q35916446 | Aging is an organ-specific process: changes in homeostasis of iron and redox proteins in the rat. |
Q42516830 | Cellular functions and transcriptional regulation of a third thioredoxin from Schizosaccharomyces pombe |
Q41138196 | Cellular responses of Saccharomyces cerevisiae at near-zero growth rates: transcriptome analysis of anaerobic retentostat cultures. |
Q41964118 | Crystallization and preliminary X-ray diffraction analysis of NADPH-dependent thioredoxin reductase I from Saccharomyces cerevisiae. |
Q27678236 | Expression, purification, crystallization and X-ray crystallographic studies of different redox states of the active site of thioredoxin 1 from the whiteleg shrimpLitopenaeus vannamei |
Q36426357 | Expression, purification, crystallization and preliminary X-ray diffraction analysis of mitochondrial thioredoxin Trx3 from Saccharomyces cerevisiae. |
Q33859467 | Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damage |
Q34229672 | Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice |
Q46093163 | High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation |
Q33852011 | Host cell targets of tegument protein VP22 of herpes simplex virus 1. |
Q28550999 | Identification of New Antifungal Compounds Targeting Thioredoxin Reductase of Paracoccidioides Genus |
Q90611601 | Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma |
Q34085212 | Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity |
Q35942706 | Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart |
Q54016161 | Oxidative Stress, Redox Imbalance, and the Aging Process |
Q36953696 | Oxidative stress impairs endothelial progenitor cell function |
Q64237970 | Proteomic Analysis of During Infection of Alveolar Macrophages Primed or Not by Interferon-Gamma |
Q90231797 | The Thioredoxin System is Regulated by the ASK-1/JNK/p38/Survivin Pathway During Germ Cell Apoptosis |
Q37212463 | The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina |
Q43204548 | Thioredoxin 1 downregulates MCP-1 secretion and expression in human endothelial cells by suppressing nuclear translocation of activator protein 1 and redox factor-1. |
Q33843037 | Thioredoxin A Is Essential for Motility and Contributes to Host Infection of Listeria monocytogenes via Redox Interactions |
Q64116077 | Thioredoxin H (TrxH) contributes to adversity adaptation and pathogenicity of Edwardsiella piscicida |
Q39822905 | Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells |
Q24683258 | Thioredoxin and ventricular remodeling |
Q53759865 | Thioredoxin gene expression in rat knee articular cartilage after full-thickness injury. |
Q33976920 | Thioredoxin glycation: A novel posttranslational modification that inhibits its antioxidant and organ protective actions |
Q39932236 | Thioredoxin overexpression modulates remodeling factors in stress responses to cigarette smoke. |
Q28389739 | Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling |
Q43050401 | Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy |
Q39023311 | WITHDRAWN: Oxidative stress in aging: Theoretical outcomes and clinical evidences in humans |
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