The Role of Thioredoxin in the Aging Process: Involvement of Oxidative Stress

scientific article published on October 1, 2003

The Role of Thioredoxin in the Aging Process: Involvement of Oxidative Stress is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1089/152308603770310211
P953full work available at URLhttp://www.liebertpub.com/doi/pdf/10.1089/152308603770310211
P698PubMed publication ID14580311

P50authorHiroshi MasutaniQ84876314
P2093author name stringJunji Yodoi
Hajime Nakamura
Toru Yoshida
Shin-ichi Oka
P2860cites workOverexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cellsQ24298232
Mutation of the mouse klotho gene leads to a syndrome resembling ageingQ24328782
High-quality life extension by the enzyme peptide methionine sulfoxide reductaseQ24530884
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.Q24533236
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.Q24535620
Aging and resistance to oxidative damage in Caenorhabditis elegansQ24561446
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanismsQ24597989
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)Q24654776
Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulationQ35451653
Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespanQ35892899
Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damageQ36459878
Expression of a vitamin D-regulated gene (VDUP-1) in untreated- and MNU-treated rat mammary tissueQ41051533
Mitochondrial expression and function of GAS-1 in Caenorhabditis elegansQ43559952
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegansQ43799857
Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxinQ45906743
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodesQ47068796
Determination of life-span in Caenorhabditis elegans by four clock genesQ47068808
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneuronsQ47991847
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span.Q48486981
A progeroid syndrome in mice is caused by defects in A-type laminsQ52105480
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.Q52543010
Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.Q53967999
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans.Q54084101
Dwarf mice and the ageing process.Q55066759
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageingQ59086518
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of agingQ63951809
Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alphaQ77754258
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylaseQ27860668
Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expressionQ28140461
Deletion of Ku86 causes early onset of senescence in miceQ28144342
Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquatQ28203333
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate proteinQ28211215
Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3Q28248159
Mutations in the WRN gene in mice accelerate mortality in a p53-null backgroundQ28510148
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone productionQ28511652
Modulation of glutathione and thioredoxin systems by calorie restriction during the aging processQ28564586
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammalsQ28587714
Premature aging in mice deficient in DNA repair and transcriptionQ28593981
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegansQ28611331
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegansQ28611332
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid systemQ28771747
Effects of development and ageing on pulmonary NADPH-cytochrome c reductase, glutathione peroxidase, glutathione reductase and thioredoxin reductase activities in male and female ratsQ29347069
Extended longevity in mice lacking the insulin receptor in adipose tissueQ29614549
The p66shc adaptor protein controls oxidative stress response and life span in mammalsQ29614553
IGF-1 receptor regulates lifespan and resistance to oxidative stress in miceQ29616382
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine functionQ29618026
Positional cloning of the Werner's syndrome geneQ29618393
ThioredoxinQ29619691
p53 mutant mice that display early ageing-associated phenotypesQ29622826
Induction of senescence-associated genes by 5-bromodeoxyuridine in HeLa cells.Q30983475
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.Q33786987
Disease states associated with telomerase deficiency appear earlier in mice with short telomeresQ33890968
Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesotheliomaQ33942829
Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosisQ34086331
Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell deathQ34134849
Redox regulation of cellular activationQ34425412
Rapid accumulation of genome rearrangements in liver but not in brain of old miceQ34449310
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous miceQ34463545
Extended life-span and stress resistance in the Drosophila mutant methuselahQ34477849
Epstein-Barr virus-containing B-cell line produces an interleukin 1 that it uses as a growth factorQ34593556
Oxidative stress and life span determination in the nematode Caenorhabditis elegansQ34614576
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.Q34763602
Redox control of cell deathQ34820717
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectphysiologyQ521
biochemistryQ7094
cell biologyQ7141
P304page(s)563-570
P577publication date2003-10-01
P1433published inAntioxidants & Redox SignalingQ4775078
P1476titleThe role of thioredoxin in the aging process: involvement of oxidative stress
The Role of Thioredoxin in the Aging Process: Involvement of Oxidative Stress
P478volume5

Reverse relations

cites work (P2860)
Q33321232A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway
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Q37212463The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina
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Q39023311WITHDRAWN: Oxidative stress in aging: Theoretical outcomes and clinical evidences in humans

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