Efficacy of the lipid-soluble iron chelator 2,2'-dipyridyl against hemorrhagic brain injury

scientific article published on 10 September 2011

Efficacy of the lipid-soluble iron chelator 2,2'-dipyridyl against hemorrhagic brain injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NBD.2011.08.028
P932PMC publication ID3225648
P698PubMed publication ID21930208
P5875ResearchGate publication ID51654498

P2093author name stringJian Wang
Tao Wu
He Wu
Mingchang Li
P2860cites workPreclinical and clinical research on inflammation after intracerebral hemorrhageQ24594191
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Cytoprotective efficacy and mechanisms of the liposoluble iron chelator 2,2'-dipyridyl in the rat photothrombotic ischemic stroke model.Q33205268
Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brainQ33281864
Effects of deferoxamine on intracerebral hemorrhage-induced brain injury in aged ratsQ33418203
White matter changes in stroke patients. Relationship with stroke subtype and outcomeQ33726713
Combination treatment of experimental stroke with Niaspan and Simvastatin, reduces axonal damage and improves functional outcomeQ33912735
Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage.Q34274102
Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage.Q34391036
The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole bloodQ34789898
White matter damage and the effect of matrix metalloproteinases in type 2 diabetic mice after strokeQ35025916
Heme and iron metabolism: role in cerebral hemorrhageQ35149704
Influence of hyperglycemia on oxidative stress and matrix metalloproteinase-9 activation after focal cerebral ischemia/reperfusion in rats: relation to blood-brain barrier dysfunctionQ35688394
New horizons for primary intracerebral hemorrhage treatment: experience from preclinical studiesQ36104043
Mechanisms of brain injury after intracerebral haemorrhage.Q36345249
Inflammation after intracerebral hemorrhageQ36620460
Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cellsQ36778839
Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in pigletsQ37219501
Superoxide production in rat hippocampal neurons: selective imaging with hydroethidineQ39428776
Failure of deferoxamine, an iron chelator, to improve outcome after collagenase-induced intracerebral hemorrhage in ratsQ39933492
Mild to moderate hyperthermia does not worsen outcome after severe intracerebral hemorrhage in rats.Q40513814
Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factorQ40972310
Iron Acquired from Transferrin by K562 Cells Is Delivered into a Cytoplasmic Pool of Chelatable Iron(II)Q41282895
Experimental intracerebral hemorrhage in rats. Magnetic resonance imaging and histopathological correlatesQ42551811
Ferrous chelator 2,2'-dipyridyl attenuates cerebral vasospasm after experimental subarachnoid haemorrhage in rabbitsQ43048712
Quantitative analysis of cell death and ferritin expression in response to cortical iron: implications for hypoxia-ischemia and strokeQ43656908
The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes.Q44066996
Temporal changes in free iron levels after brain ischemia Relevance to the timing of iron chelation therapy in stroke.Q46591323
Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2'-dipyridyl.Q46714617
Beneficial effect of dipyridyl, a liposoluble iron chelator against focal cerebral ischemia: in vivo and in vitro evidence of protection of cerebral endothelial cells.Q46821417
Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouseQ46922857
c-Jun N-terminal kinase pathway inhibition in intracerebral hemorrhageQ48245110
Contributions of multiple proteases to neurotoxicity in a mouse model of intracerebral haemorrhageQ48938506
A multiple course trial of desferrioxamine in chronic progressive multiple sclerosisQ73942282
Role of ferrous iron chelator 2,2'-dipyridyl in preventing delayed vasospasm in a primate model of subarachnoid hemorrhageQ74128320
THE BIOCHEMISTRY OF DESFERRIOXAMINE AND ITS RELATION TO IRON METABOLISMQ76985464
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)388-394
P577publication date2011-09-10
P1433published inNeurobiology of DiseaseQ15716606
P1476titleEfficacy of the lipid-soluble iron chelator 2,2'-dipyridyl against hemorrhagic brain injury
P478volume45

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cites work (P2860)
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