review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1152/AJPENDO.00324.2003 |
P953 | full work available at URL | http://intl-ajpendo.physiology.org/cgi/content/abstract/285/6/E1151 |
https://www.physiology.org/doi/pdf/10.1152/ajpendo.00324.2003 | ||
P698 | PubMed publication ID | 14607781 |
P5875 | ResearchGate publication ID | 9017115 |
P50 | author | Philipp E. Scherer | Q60572448 |
Michael P. Lisanti | Q77913186 | ||
P2093 | author name string | Terry P. Combs | |
Alex W. Cohen | |||
P2860 | cites work | CAP defines a second signalling pathway required for insulin-stimulated glucose transport | Q24290287 |
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette | Q24290507 | ||
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10 | Q24291135 | ||
Insulin signalling and the regulation of glucose and lipid metabolism | Q24292020 | ||
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family | Q24315913 | ||
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins | Q24322008 | ||
Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo | Q24324547 | ||
Mechanisms of nutritional and hormonal regulation of lipogenesis | Q24522517 | ||
Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway | Q28189761 | ||
Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system | Q28212772 | ||
Regulated transport of the glucose transporter GLUT4 | Q28216848 | ||
Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities | Q28255025 | ||
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle | Q28273695 | ||
Caveolin is an activator of insulin receptor signaling | Q28284137 | ||
Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins | Q28304307 | ||
Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice | Q28369792 | ||
Caveolin-1 and caveolin-2 expression in mouse macrophages. High density lipoprotein 3-stimulated secretion and a lack of significant subcellular co-localization | Q28507990 | ||
Caveolae-associated proteins in cardiomyocytes: caveolin-2 expression and interactions with caveolin-3 | Q28578902 | ||
Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling | Q28581283 | ||
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice | Q29615180 | ||
Activation of glycogen synthase by insulin in 3T3-L1 adipocytes involves c-Cbl-associating protein (CAP)-dependent and CAP-independent signaling pathways. | Q30168433 | ||
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation | Q30441963 | ||
Isolation and lipid characterization of cholesterol-enriched fractions in cortical and nuclear human lens fibers | Q31136232 | ||
Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control | Q31716904 | ||
On the control of lipolysis in adipocytes | Q33936993 | ||
Lipid rafts are required for GLUT4 internalization in adipose cells | Q33946982 | ||
Caveolins in cholesterol trafficking and signal transduction: implications for human disease. | Q34095985 | ||
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance | Q34137882 | ||
Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways | Q34159434 | ||
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. | Q34451462 | ||
Caveolin-deficient mice: insights into caveolar function human disease | Q34457018 | ||
Insulin signaling pathways in time and space. | Q34534983 | ||
The fine structure of the gall bladder epithelium of the mouse. | Q34537858 | ||
Mouse models of insulin resistance | Q34588917 | ||
IRS proteins and the common path to diabetes | Q34778267 | ||
Functional properties of a naturally occurring Trp1200----Ser1200 mutation of the insulin receptor | Q34994283 | ||
SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis. | Q35888471 | ||
Cholesterol depletion blocks redistribution of lipid raft components and insulin-mimetic signaling by glimepiride and phosphoinositolglycans in rat adipocytes | Q36087982 | ||
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles | Q36234898 | ||
Expression and compartmentalization of caveolin in adipose cells: coordinate regulation with and structural segregation from GLUT4. | Q36235656 | ||
Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation | Q36323578 | ||
A mutation (Trp1193-->Leu1193) in the tyrosine kinase domain of the insulin receptor associated with type A syndrome of insulin resistance | Q38319653 | ||
Hsp70 family molecular chaperones and mutant insulin receptor: differential binding specificities of BiP and Hsp70/Hsc70 determines accumulation or degradation of insulin receptor | Q38362717 | ||
Redistribution of glycolipid raft domain components induces insulin-mimetic signaling in rat adipocytes | Q39459824 | ||
Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I. | Q40702179 | ||
Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae | Q40736924 | ||
Mutational analysis identifies a short atypical membrane attachment sequence (KYWFYR) within caveolin-1. | Q40745371 | ||
Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins | Q40814974 | ||
A molecular dissection of caveolin-1 membrane attachment and oligomerization. Two separate regions of the caveolin-1 C-terminal domain mediate membrane binding and oligomer/oligomer interactions in vivo | Q40881286 | ||
Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions | Q41127799 | ||
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane | Q41715384 | ||
Insulin-stimulated glucose uptake involves the transition of glucose transporters to a caveolae-rich fraction within the plasma membrane: implications for type II diabetes | Q41809606 | ||
Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes | Q41861046 | ||
Insulin stimulates the tyrosine phosphorylation of caveolin | Q41881930 | ||
The adipocyte plasma membrane caveolin functional/structural organization is necessary for the efficient endocytosis of GLUT4. | Q42434971 | ||
Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells | Q42442501 | ||
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes | Q42483514 | ||
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue | Q42803748 | ||
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity | Q42809229 | ||
The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes | Q42809492 | ||
The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1. | Q42814621 | ||
Caveolin-1 expression enhances endothelial capillary tubule formation | Q42822849 | ||
Insulin induces translocation of glucose transporter GLUT4 to plasma membrane caveolae in adipocytes. | Q42822979 | ||
Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TY | Q43672984 | ||
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities | Q43678714 | ||
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation during the lactation cycle of the rat. | Q43792591 | ||
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities | Q43819817 | ||
Glutamate regulates caveolin expression in rat hippocampal neurons | Q44387884 | ||
Cellular apoptosis is associated with increased caveolin-1 expression in macrophages | Q44460196 | ||
Crowded little caves: structure and function of caveolae | Q47329891 | ||
Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain | Q47881243 | ||
Functional studies on native and mutated forms of perilipins. A role in protein kinase A-mediated lipolysis of triacylglycerols. | Q51840956 | ||
Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome. | Q54136053 | ||
Insulin and alpha 2-macroglobulin-methylamine undergo endocytosis by different mechanisms in rat adipocytes: II. Comparison of intracellular events | Q68204681 | ||
Insulin and alpha 2-macroglobulin-methylamine undergo endocytosis by different mechanisms in rat adipocytes: I. Comparison of cell surface events | Q69010358 | ||
Translocation of perilipin and hormone-sensitive lipase in response to lipolytic hormones | Q74119305 | ||
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance | Q77652485 | ||
A role for the caveolin scaffolding domain in mediating the membrane attachment of caveolin-1. The caveolin scaffolding domain is both necessary and sufficient for membrane binding in vitro | Q78069859 | ||
Effects of deleting a tripeptide sequence observed in muscular dystrophy patients on the conformation of synthetic peptides corresponding to the scaffolding domain of caveolin-3 | Q78395500 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | signal transduction | Q828130 |
physiology | Q521 | ||
preproinsulin | Q7240673 | ||
P304 | page(s) | E1151-60 | |
P577 | publication date | 2003-12-01 | |
P1433 | published in | American Journal of Physiology - Endocrinology and Metabolism | Q15765671 |
P1476 | title | Role of caveolin and caveolae in insulin signaling and diabetes | |
P478 | volume | 285 |
Q51388970 | 17β-Estradiol attenuates diet-induced insulin resistance and glucose intolerance through up-regulation of caveolin-3 |
Q47806485 | A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal |
Q45090662 | A potential role for skeletal muscle caveolin-1 as an insulin sensitivity modulator in ageing-dependent non-obese type 2 diabetes: studies in a new mouse model. |
Q30829796 | Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects--a monozygotic twin study |
Q47241904 | Adipocyte size and cellular expression of caveolar proteins analyzed by confocal microscopy |
Q54070055 | Akt and RhoA activation in response to high glucose require caveolin-1 phosphorylation in mesangial cells. |
Q64067839 | Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling |
Q36844820 | Aldehydes and disturbance of carbohydrate metabolism: some consequences and possible approaches to its normalization |
Q37589401 | An association of metabolic syndrome constellation with cellular membrane caveolae |
Q37054501 | Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia |
Q49832016 | Causes and mechanisms of adipocyte enlargement and adipose expansion |
Q43053160 | Caveolin expression and activation in retroperitoneal and subcutaneous adipocytes: influence of a high-fat diet |
Q40481718 | Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling. |
Q42472553 | Caveolin-1-ablated mice survive in cold by nonshivering thermogenesis despite desensitized adrenergic responsiveness. |
Q45249911 | Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle |
Q42041952 | Cholesterol accumulation in podocytes: a potential novel targetable pathway in diabetic nephropathy |
Q37403959 | Compartmentalization and regulation of insulin signaling to GLUT4 by the cytoskeleton |
Q34559663 | Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering |
Q35688763 | Diabetes and Alzheimer's disease - is there a connection? |
Q64264709 | Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice |
Q54977385 | Directed evolution and biophysical characterization of a full-length, soluble, human caveolin-1 variant. |
Q30479891 | Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance |
Q28473861 | Downregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cells |
Q42802278 | Effects of statins on the adipocyte maturation and expression of glucose transporter 4 (SLC2A4): implications in glycaemic control |
Q30412212 | Endothelial cells actively concentrate insulin during its transendothelial transport |
Q35853499 | Essential role of caveolin-3 in adiponectin signalsome formation and adiponectin cardioprotection |
Q28472170 | Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications |
Q37022485 | Fluorescence techniques using dehydroergosterol to study cholesterol trafficking |
Q54645797 | GLUT4 in murine bone growth: from uptake and translocation to proliferation and differentiation |
Q64100803 | Gene Expression Essential for Myostatin Signaling and Skeletal Muscle Development Is Associated With Divergent Feed Efficiency in Pedigree Male Broilers |
Q36327829 | Glucose transporter 4: cycling, compartments and controversies |
Q57359108 | High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: Implications for atherosclerosis |
Q34871681 | High-fat diet feeding alters metabolic response to fasting/non fasting conditions. Effect on caveolin expression and insulin signalling. |
Q28581080 | High-fat feeding period affects gene expression in rat white adipose tissue |
Q54410521 | Homeorhetic adaptation to lactation: comparative transcriptome analysis of mammary, liver, and adipose tissue during the transition from pregnancy to lactation in rats. |
Q36053009 | IRS-1 and vascular complications in diabetes mellitus |
Q37310649 | Identification of pY19-caveolin-2 as a positive regulator of insulin-stimulated actin cytoskeleton-dependent mitogenesis |
Q36888387 | Ins (endocytosis) and outs (exocytosis) of GLUT4 trafficking |
Q28081458 | Insulin resistance and skeletal muscle vasculature: significance, assessment and therapeutic modulators |
Q91597367 | Intermittent hypoxia regulates vasoactive molecules and alters insulin-signaling in vascular endothelial cells |
Q37731174 | Intestinal epithelial cell caveolin 1 regulates fatty acid and lipoprotein cholesterol plasma levels |
Q34525661 | Introduction of caveolae structural proteins into the protozoan Toxoplasma results in the formation of heterologous caveolae but not caveolar endocytosis |
Q33784630 | Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects. |
Q36825607 | Lipid mediators in membrane rafts are important determinants of human health and disease |
Q43208933 | Little caves ameliorate hepatic insulin signaling. Focus on "caveolin gene transfer improves glucose metabolism in diabetic mice". |
Q37109719 | Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma |
Q42575923 | Man overboard! Rescuing myocardium with membrane rafts |
Q28240056 | MicroRNAs 103 and 107 regulate insulin sensitivity |
Q34500679 | Modulation of insulin sensitivity and caveolin-1 expression by orchidectomy in a nonobese type 2 diabetes animal model |
Q36888572 | Molecular determinants of endothelial transcytosis and their role in endothelial permeability |
Q34335027 | Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha |
Q46034115 | Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection. |
Q36099612 | NOX4 pathway as a source of selective insulin resistance and responsiveness |
Q46346105 | Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney--another reason for diabetic nephropathy? |
Q46897514 | Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury |
Q35945161 | Obesity-associated improvements in metabolic profile through expansion of adipose tissue |
Q26774272 | Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases |
Q33882371 | Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis |
Q33415060 | Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism |
Q64266446 | Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes |
Q30474192 | Physiopathological function of hematoside (GM3 ganglioside). |
Q38927815 | Pre-B cell colony enhancing factor induces Nampt-dependent translocation of the insulin receptor out of lipid microdomains in A549 lung epithelial cells |
Q36951401 | Proteomics of Breast Muscle Tissue Associated with the Phenotypic Expression of Feed Efficiency within a Pedigree Male Broiler Line: I. Highlight on Mitochondria |
Q34178976 | Pulmonary hypertension and metabolic syndrome: Possible connection, PPARγ and Caveolin-1 |
Q33471497 | Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes |
Q40283407 | Regulation of insulin response in skeletal muscle cell by caveolin status. |
Q37278319 | Regulation of renal organic anion transporter 3 (SLC22A8) expression and function by the integrity of lipid raft domains and their associated cytoskeleton |
Q21558622 | Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function |
Q64981133 | SMPDL3b modulates insulin receptor signaling in diabetic kidney disease. |
Q37106885 | SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cells |
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