The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis

scientific article published on 23 March 2015

The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1020318C
P356DOI10.1371/JOURNAL.PONE.0120318
P8608Fatcat IDrelease_ey4ftz7gsvfb3imtk5p36ym66e
P932PMC publication ID4370575
P698PubMed publication ID25799589
P5875ResearchGate publication ID277580562

P50authorGary S ShawQ58929854
P2093author name stringBrian H Shilton
Kathryn R Barber
Benjamin W Cook
P2860cites workA 25-kilodalton ubiquitin carrier protein (E2) catalyzes multi-ubiquitin chain synthesis via lysine 48 of ubiquitinQ44594917
Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly.Q45029738
Sequential E2s drive polyubiquitin chain assembly on APC targetsQ46225392
Diverse polyubiquitin interaction properties of ubiquitin-associated domainsQ46592679
Ubiquitin manipulation by an E2 conjugating enzyme using a novel covalent intermediate.Q46598593
Direct catalysis of lysine 48-linked polyubiquitin chains by the ubiquitin-activating enzymeQ46939294
Structure and Function of Ubiquitin Conjugating Enzyme E2-25K: The Tail Is a Core-Dependent Activity ElementQ54559660
The tail of a ubiquitin-conjugating enzyme redirects multi-ubiquitin chain synthesis from the lysine 48-linked configuration to a novel nonlysine-linked formQ71763289
Multiubiquitin chains linked through lysine 48 are abundant in vivo and are competent intermediates in the ubiquitin proteolytic pathwayQ72571808
Identification of the ubiquitin interfacial residues in a ubiquitin-E2 covalent complexQ73493455
A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitinationQ82857335
Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymesQ84076866
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13Q24291487
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrateQ24297635
Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateQ24304915
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimerQ27633059
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tailQ27635260
Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2Q27653834
Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2)Q27655342
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexQ27658921
Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and NeurotoxicityQ27664383
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysisQ27670947
Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin ConjugatesQ27678872
The ubiquitin systemQ27860803
An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysisQ28207621
Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formationQ29619698
CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic CoordinatesQ29642130
Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniquesQ30447247
Catalytic proficiency of ubiquitin conjugation enzymes: balancing pK(a) suppression, entropy, and electrostatics.Q33757691
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.Q34090989
Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent HomodimerQ34346819
A new multiphasic buffer system for sodium dodecyl sulfate-polyacrylamide gel electrophoresis of proteins and peptides with molecular masses 100,000-1000, and their detection with picomolar sensitivityQ34594404
Lingering mysteries of ubiquitin-chain assemblyQ36368593
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e0120318
P577publication date2015-03-23
P1433published inPLOS OneQ564954
P1476titleThe HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis
P478volume10

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cites work (P2860)
Q37603509E2-25K SUMOylation inhibits proteasome for cell death during cerebral ischemia/reperfusion
Q89893269Recruitment of Ubiquitin within an E2 Chain Elongation Complex
Q40291384The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.

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