Overexpression/amplification of HER-2/neu is uncommon in hepatocellular carcinoma

scientific article published on May 2005

Overexpression/amplification of HER-2/neu is uncommon in hepatocellular carcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/JCP.2004.023556
P932PMC publication ID1770655
P698PubMed publication ID15858121
P5875ResearchGate publication ID7880212

P2093author name stringM-C Wu
S-H Zhang
W-M Cong
W-Q Wu
Z-H Xian
P2860cites workAssociation between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patientsQ46464385
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenograftsQ47854934
Accuracy and precision in HER2/neu testing in breast cancer: are we there yet?Q48021220
Determination of the oncogenes p53 and C-erb B2 in the tumour cytosols of advanced hepatocellular carcinoma (HCC) and correlation to survival time.Q52977312
C-erb-B-2 oncoprotein and epidermal growth factor receptor in human hepatocellular carcinoma: an immunohistochemical studyQ72639491
Specificity of HercepTest in determining HER-2/neu status of breast cancers using the United States Food and Drug Administration-approved scoring systemQ73181576
Evaluation of HER-2/neu immunohistochemical assay sensitivity and scoring on formalin-fixed and paraffin-processed cell lines and breast tumors: a comparative study involving results from laboratories in 21 countriesQ74761182
Treatment of hepatocellular carcinomaQ77096102
The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapyQ28191663
Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancerQ33598660
Biologic and therapeutic role of HER2 in cancerQ34267775
The prognostic molecular markers in hepatocellular carcinomaQ34668320
Laboratory assessment of the status of Her-2/neu protein and oncogene in breast cancer specimens: comparison of immunohistochemistry assay with fluorescence in situ hybridisation assaysQ35396369
Best Practice No 176: Updated recommendations for HER2 testing in the UKQ35587451
Use of tissue microarray for interlaboratory validation of HER2 immunocytochemical and FISH testingQ35588100
Expression and clinical significance of erb-B receptor family in hepatocellular carcinomaQ36622264
Incidence, mechanism and prognostic value of activated AKT in pancreas cancerQ36648105
P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.Q40550119
Treatment of HER-2/neu overexpressing breast cancer xenograft models with trastuzumab (Herceptin) and gefitinib (ZD1839): drug combination effects on tumor growth, HER-2/neu and epidermal growth factor receptor expression, and viable hypoxic cell frQ40568575
Expression of Her-2/neu in human lung cancer cell lines by immunohistochemistry and fluorescence in situ hybridization and its relationship to in vitro cytotoxicity by trastuzumab and chemotherapeutic agentsQ40775553
Epidermal growth factor receptor expression is a candidate target of the synergistic combination of trastuzumab and flavopiridol in breast cancer.Q42163064
Guidelines for HER2 testing in the UK.Q43010802
Progress in research of liver surgery in China.Q43064716
c-erbB-2 oncogene expression in hepatocellular carcinoma and cholangiocarcinomaQ43526977
HER-2/neu overexpression is rare in hepatocellular carcinoma and not predictive of anti-HER-2/neu regulation of cell growth and chemosensitivityQ43921056
C-erb B2 (Her2/neu) is neither overexpressed nor amplified in hepatic neoplasmsQ44174661
Feasibility of using tissue microarrays for the assessment of HER-2 gene amplification by fluorescence in situ hybridization in breast carcinomaQ46227456
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.Q46246951
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectoverexpressionQ61643320
P304page(s)500-503
P577publication date2005-05-01
P1433published inJournal of Clinical PathologyQ6294965
P1476titleOverexpression/amplification of HER-2/neu is uncommon in hepatocellular carcinoma
P478volume58

Reverse relations

cites work (P2860)
Q64129433Combined therapy of transcatheter hepatic arterial embolization with intratumoral dendritic cell infusion for hepatocellular carcinoma: clinical safety
Q36519010Dysregulation of growth factor signaling in human hepatocellular carcinoma.
Q28078111HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists
Q37639917Hepatitis B virus X upregulates HuR protein level to stabilize HER2 expression in hepatocellular carcinoma cells.
Q38073827Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers
Q64279990Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence
Q58693837Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib
Q42180761TOP2A amplification and overexpression in hepatocellular carcinoma tissues.
Q54942120The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice.
Q36395424The Predictive and Prognostic Significance of c-erb-B2, EGFR, PTEN, mTOR, PI3K, p27, and ERCC1 Expression in Hepatocellular Carcinoma
Q38959732The interrelationship between HER2 and CASP3/8 with apoptosis in different cancer cell lines.
Q80554209[Molecular pathogenesis of hepatocellular carcinoma: new therapeutic approaches and predictive pathology]
Q50091796[Nuclear Her2 expression in hepatocytes in liver disease].

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