Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women

scientific article published on January 2015

Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/QAD.0000000000000531
P932PMC publication ID4428759
P698PubMed publication ID25426808
P5875ResearchGate publication ID268875570

P50authorDiane HavlirQ55950716
Veronica AdesQ56379715
Julia MwesigwaQ56786347
Moses R KamyaQ60043817
Edwin D CharleboisQ75159249
Monica GandhiQ90832467
Tamara ClarkQ91182117
Deborah CohanQ92167251
Jane AchanQ102203903
Albert H J PlentyQ114439178
Theodore D RuelQ114439179
Paul NatureebaQ114439180
Flavia A LuweddeQ114439181
Bridget NzarubaraQ114439195
Catherine A KossQ114439199
P2860cites workPrevention of HIV-1 infection with early antiretroviral therapyQ24634688
Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeedingQ30679524
Effect of early versus deferred antiretroviral therapy for HIV on survivalQ33789114
Triple-antiretroviral prophylaxis to prevent mother-to-child HIV transmission through breastfeeding--the Kisumu Breastfeeding Study, Kenya: a clinical trialQ33863552
Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohortsQ34116017
Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysisQ34216455
Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in BotswanaQ34306176
Antiretroviral regimens in pregnancy and breast-feeding in BotswanaQ34395082
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South AfricaQ34431819
Low lopinavir plasma or hair concentrations explain second-line protease inhibitor failures in a resource-limited settingQ34778123
Atazanavir concentration in hair is the strongest predictor of outcomes on antiretroviral therapyQ34814795
Lopinavir/ritonavir-based antiretroviral treatment (ART) versus efavirenz-based ART for the prevention of malaria among HIV-infected pregnant womenQ34974794
Risk factors for preterm birth among HIV-infected pregnant Ugandan women randomized to lopinavir/ritonavir- or efavirenz-based antiretroviral therapyQ35551457
Lopinavir tablet pharmacokinetics with an increased dose during pregnancyQ35691909
Maternal or infant antiretroviral drugs to reduce HIV-1 transmissionQ36231035
Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trialQ36866309
Protease inhibitor levels in hair strongly predict virologic response to treatmentQ37124640
Sensitive analysis of anti-HIV drugs, efavirenz, lopinavir and ritonavir, in human hair by liquid chromatography coupled with tandem mass spectrometryQ37159364
Adherence to antiretroviral therapy during and after pregnancy in low-income, middle-income, and high-income countries: a systematic review and meta-analysisQ37335159
Class-sparing regimens for initial treatment of HIV-1 infectionQ37454026
Pharmacokinetics of lopinavir/ritonavir and efavirenz in food insecure HIV-infected pregnant and breastfeeding women in Tororo, UgandaQ37600844
Safety of antiretroviral drugs in pregnancy and breastfeeding for mother and childQ38112591
Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomised controlled trialQ38967453
A 96-week comparison of lopinavir-ritonavir combination therapy followed by lopinavir-ritonavir monotherapy versus efavirenz combination therapy.Q40082978
Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating mothers with triple antiretroviral therapy in Dar es Salaam, Tanzania: the Mitra Plus studyQ43281055
Reduced lopinavir exposure during pregnancyQ46112061
Association of Prenatal and Postnatal Exposure to Lopinavir-Ritonavir and Adrenal Dysfunction Among Uninfected Infants of HIV-Infected MothersQ56762683
Antiretroviral therapies in pregnancy: maternal, fetal and neonatal effects. Swiss HIV Cohort Study, the Swiss Collaborative HIV and Pregnancy Study, and the Swiss Neonatal HIV StudyQ77754217
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectUgandaQ1036
lopinavirQ422585
ritonavirQ422618
efavirenzQ422645
lopinavir/ritonavirQ3836750
anti-retroviral agentQ50430310
P304page(s)183-191
P577publication date2015-01-01
P1433published inAIDSQ4651863
P1476titleEfficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women
P478volume29

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cites work (P2860)
Q30381808A Systematic Review of Interventions to Reduce Maternal Mortality among HIV-Infected Pregnant and Postpartum Women
Q59802846Achieving UNAIDS 90-90-90 targets for pregnant and postpartum women in sub-Saharan Africa: progress, gaps and research needs
Q39234019Advances in therapy for the prevention of HIV transmission from mother to child
Q59128516Adverse effects of antiretroviral therapy in pregnant women infected with HIV in Brazil from 2000 to 2015: a cohort study
Q95643468Anemia and Micronutrient Status during Pregnancy, and Their Associations with Obstetric and Infant Outcomes among HIV-Infected Ugandan Women Receiving Antiretroviral Therapy
Q36576508Brief Report: Food Insufficiency Is Associated With Lack of Sustained Viral Suppression Among HIV-Infected Pregnant and Breastfeeding Ugandan Women
Q90074397Brief Report: Markers of Spontaneous Preterm Delivery in Women Living With HIV: Relationship With Protease Inhibitors and Vitamin D
Q38961883Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis
Q47724822Development and Validation of an Assay to Analyze Atazanavir in Human Hair Via Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Q92535721Efficacy and Tolerability of Lopinavir/Ritonavir- and Efavirenz-Based Initial Antiretroviral Therapy in HIV-1-Infected Patients in a Tertiary Care Hospital in Beijing, China
Q45324863Estradiol Levels Are Altered in Human Immunodeficiency Virus-Infected Pregnant Women Randomized to Efavirenz-Versus Lopinavir/Ritonavir-Based Antiretroviral Therapy
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