CD4 T cell depletion at the cervix during HIV infection is associated with accumulation of terminally differentiated T cells.

scientific article published on 12 October 2011

CD4 T cell depletion at the cervix during HIV infection is associated with accumulation of terminally differentiated T cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.05671-11
P932PMC publication ID3233181
P698PubMed publication ID21994461

P50authorAnna-Lise WilliamsonQ20721396
Wendy A. BurgersQ42225589
P2093author name stringW Hanekom
D Coetzee
J S Passmore
A L Salkinder
N N Mkhize
P P Gumbi
S Z Jaumdally
P2860cites workImmune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infectionQ24795912
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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infectionQ29619124
Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical statusQ33381538
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Expression of mucosal homing receptor alpha4beta7 is associated with enhanced migration to the Chlamydia-infected murine genital mucosa in vivoQ33591433
Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cellsQ33817158
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The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.Q37428017
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Influence of sex hormones, HIV status, and concomitant sexually transmitted infection on cervicovaginal inflammationQ37865803
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Current status of syndromic management of sexually transmitted infections in developing countriesQ43061456
Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tractQ45381621
Distribution of simian immunodeficiency virus target cells in vaginal tissues of normal rhesus macaques: implications for virus transmissionQ45412529
Chronic alcohol consumption results in higher simian immunodeficiency virus replication in mucosally inoculated rhesus macaquesQ45415242
Pathogenesis of HIV infection: what the virus spares is as important as what it destroysQ45419109
Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunizationQ45729375
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Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population.Q51985053
HIV: viral blitzkrieg.Q51992509
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.Q51993308
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Phenotypic and functional characterization of lymphocytes derived from normal and HIV-1-infected human lymph nodes.Q52033117
single-cell cytokine analysis allows detection of cervical T-cell responses against human papillomavirus type 16 L1 in women infected with genital HPVQ58165561
P433issue24
P407language of work or nameEnglishQ1860
P304page(s)13333-13341
P577publication date2011-10-12
P1433published inJournal of VirologyQ1251128
P1476titleCD4 T cell depletion at the cervix during HIV infection is associated with accumulation of terminally differentiated T cells
P478volume85

Reverse relations

cites work (P2860)
Q36618563ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions
Q38635598Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy
Q40248163CCR5 expression, haplotype and immune activation in protection from infection in HIV-exposed uninfected individuals in HIV-serodiscordant relationships
Q37671931HIV Infection in Uncircumcised Men Is Associated With Altered CD8 T-cell Function But Normal CD4 T-cell Numbers in the Foreskin
Q37626039Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women
Q33390618Presence of CD8+ T cells in the ectocervical mucosa correlates with genital viral shedding in HIV-infected women despite a low prevalence of HIV RNA-expressing cells in the tissue
Q92736069T Cells in the Female Reproductive Tract Can Both Block and Facilitate HIV Transmission

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