Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice

scientific article published on 23 September 2011

Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00052.2011
P932PMC publication ID3233816
P698PubMed publication ID21949117
P5875ResearchGate publication ID51665159

P2093author name stringThomas Krahn
Catherine Ledent
Stephen Tilley
S Jamal Mustafa
Bunyen Teng
Maryam Sharifi Sanjani
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Adenosine mediates relaxation of human small resistance-like coronary arteries via A2B receptorsQ35056733
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Coronary pressure-flow relations as basis for the understanding of coronary physiologyQ37917169
DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.Q39764820
Adenosine 2B receptor expression is post-transcriptionally regulated by microRNAQ40915393
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cellsQ41534022
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Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channelsQ42005946
Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblastsQ42285045
A new ATP-sensitive potassium channel opener protects endothelial function in cultured aortic endothelial cellsQ42504396
Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.Q42650403
Adenosine and maximum coronary vasodilation in humans: myth and misconceptions in the assessment of coronary reserveQ43235112
HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxiaQ43258538
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cellsQ43505742
Activation of barium-sensitive inward rectifier potassium channels mediates remote dilation of coronary arteriolesQ43760012
Cardiac effects of adenosine in A(2A) receptor knockout hearts: uncovering A(2B) receptorsQ43852650
Gender-specific K(+)-channel contribution to adenosine-induced relaxation in coronary arteriolesQ43858064
Role of endothelium in adenosine receptor-mediated vasorelaxation in hypertensive ratsQ43923378
Differential expression of adenosine receptors in human endothelial cells: role of A2B receptors in angiogenic factor regulationQ43928343
Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heartQ43988594
Involvement of K+ channels in adenosine A2A and A2B receptor-mediated hyperpolarization of porcine coronary artery endothelial cellsQ44033559
Endogenous adenosine increases coronary flow by activation of both A2A and A2B receptors in miceQ44376976
Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels.Q44451725
Effects of aging and ischemia on adenosine receptor transcription in mouse myocardiumQ44668568
Effects of xylazine on canine coronary artery vascular ringsQ44839489
Evidence for the involvement of nitric oxide in A2B receptor-mediated vasorelaxation of mouse aortaQ44922677
Effect of intracoronary adenosine infusion during coronary intervention on myocardial reperfusion injury in patients with acute myocardial infarctionQ44953145
Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotypeQ45081311
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascadeQ45214796
Involvement of p38-mitogen-activated protein kinase in adenosine receptor-mediated relaxation of coronary arteryQ45226681
Adenosine A2A receptor hyperexpression in patients with severe SIRS after cardiopulmonary bypassQ46454472
Intravenous adenosine reduces myocardial no-reflow by decreasing endothelin-1 via activation of the ATP-sensitive K+ channelQ46457605
Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosineQ46508363
Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioningQ46509525
A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).Q46528602
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.Q46562981
Activation of inward rectifier K+ channels by hypoxia in rabbit coronary arterial smooth muscle cellsQ46801078
Impact of adenosine receptor signaling and metabolism on pathophysiology in patients with chronic heart failureQ46882668
The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cellsQ46887393
Role of A1 adenosine receptor in the regulation of coronary flowQ46976018
Immunological characterization of adenosine A2A receptors in human and porcine cardiovascular tissues.Q47723216
Intravenous adenosine and lidocaine in patients with acute myocardial infarction.Q51505291
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Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig.Q53867227
P433issue6
P921main subjectknockout mouseQ1364740
P304page(s)H2322-33
P577publication date2011-09-23
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleContributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice
P478volume301

Reverse relations

cites work (P2860)
Q37440228A1 adenosine receptor negatively modulates coronary reactive hyperemia via counteracting A2A-mediated H2O2 production and KATP opening in isolated mouse hearts
Q52345426Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors.
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Q33165093Cardiac purinergic signalling in health and disease
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Q36510139Enhanced A2A adenosine receptor-mediated increase in coronary flow in type I diabetic mice.
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Q36334362Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1
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Q35587846Involvement of NADPH oxidase in A2A adenosine receptor-mediated increase in coronary flow in isolated mouse hearts
Q34295446Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts
Q96303477Purinergic Signaling During Hyperglycemia in Vascular Smooth Muscle Cells
Q36618711Role of Adenosine Receptor(s) in the Control of Vascular Tone in the Mouse Pudendal Artery
Q37370573Spare Adenosine A2a Receptors Are Associated With Positive Exercise Stress Test In Coronary Artery Disease.
Q37990558Targeting adenosine receptors in the development of cardiovascular therapeutics

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