Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome

scientific article published on 21 July 2011

Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00125-011-2248-8
P932PMC publication ID4430553
P698PubMed publication ID21779871
P5875ResearchGate publication ID51512295

P50authorGiovanna MuscogiuriQ51281723
P2093author name stringK Clark
R L Reddick
F Jimenez
C A Estrada
S S Ahuja
N Musi
G Sorice
H G Martinez
M P Quinones
P2860cites workObesity is associated with macrophage accumulation in adipose tissueQ27860976
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Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.Q28590391
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesityQ29614283
Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination SurveyQ29614468
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein EQ29615236
The many roles of chemokines and chemokine receptors in inflammationQ29618880
CCR2 modulates inflammatory and metabolic effects of high-fat feedingQ29622869
Leukocyte recruitment and vascular injury in diabetic nephropathyQ30439127
Hypercholesterolemia reduces collateral artery growth more dominantly than hyperglycemia or insulin resistance in miceQ30811222
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout miceQ30891436
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Body fat distribution and inflammation among obese older adults with and without metabolic syndromeQ34985484
Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidenceQ36177005
Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.Q36279580
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The metabolic syndrome. Beyond the insulin resistance syndrome.Q36484070
Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3.Q36538348
Chemokine regulation of atherosclerosisQ36747915
Proteinuria in diabetes: bystander or pathway to cardiorenal disease?Q37807211
Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese miceQ38314767
Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cellsQ39950939
Macrophage-secreted factors induce adipocyte inflammation and insulin resistanceQ40326610
Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscleQ42522942
Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance.Q42962656
Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets.Q45989922
Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11beta-HSD1, PEPCK and DGAT2. Comparison of PPARalpha, PPARgamma, and liver x receptor agonistsQ46107767
Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice.Q46345972
Morphometric analysis of effects of angiotensin II on glomerular structure in ratsQ46427323
Genetics of obesity in KK mouse and effects of A(y) allele on quantitative regulationQ47869515
Nodular thickening of peritubular basement membranes in diabetic kidneysQ50958249
Involvement of apolipoprotein E in excess fat accumulation and insulin resistanceQ64377348
Adiponectin replenishment ameliorates obesity-related hypertensionQ64377846
Mesangial thickening and nodular glomerular sclerosis in diabetes mellitus and other diseasesQ70512262
General Survey of Diabetic Features of Yellow KK MiceQ71566421
Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient miceQ77340592
CC chemokine receptor 5 influences late-stage atherosclerosisQ80232714
Trends in incidence of treated end-stage renal disease, overall and by primary renal disease, in persons aged 20-64 years in Europe, Canada and the Asia-Pacific region, 1998-2002Q81095258
Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitusQ83143491
P4510describes a project that usesImageJQ1659584
P433issue10
P921main subjectmetabolic syndromeQ657193
P304page(s)2660-2668
P577publication date2011-07-21
P1433published inDiabetologiaQ5270140
P1476titleCritical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome
P478volume54