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| P50 | author | John Q. Trojanowski | Q6253636 |
| Murray Grossman | Q66724764 | ||
| Manuela Neumann | Q66730291 | ||
| P2093 | author name string | Deepak M Sampathu | |
| Jennifer Bruce | |||
| Linda K Kwong | |||
| Thomas T Chou | |||
| Virginia M-Y Lee | |||
| Adam Truax | |||
| Matthew Micsenyi | |||
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| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | monoclonal antibody | Q422248 |
| frontotemporal lobar degeneration | Q18579 | ||
| antibody | Q79460 | ||
| immunohistochemistry | Q899285 | ||
| P304 | page(s) | 1343-1352 | |
| P577 | publication date | 2006-10-01 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies | |
| P478 | volume | 169 |
| Q28488462 | A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration |
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| Q36609145 | A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity |
| Q29417099 | ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology |
| Q33571116 | ALS and FTLD: two faces of TDP-43 proteinopathy |
| Q35674883 | Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration |
| Q36775677 | Advances in understanding the molecular basis of frontotemporal dementia |
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| Q34059809 | Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations |
| Q47875656 | Amygdala TDP-43 Pathology in Frontotemporal Lobar Degeneration and Motor Neuron Disease |
| Q35092787 | Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies |
| Q37409270 | Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases |
| Q34023599 | Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium |
| Q33871696 | Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation |
| Q36603819 | Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions. |
| Q46686145 | Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions |
| Q35014879 | Brain progranulin expression in GRN-associated frontotemporal lobar degeneration |
| Q35103955 | Brainstem: neglected locus in neurodegenerative diseases. |
| Q45231223 | Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice |
| Q57306364 | Chapter 7 Ubiquitinopathies |
| Q33715607 | Classification of FTLD-TDP cases into pathological subtypes using antibodies against phosphorylated and non-phosphorylated TDP43. |
| Q34028511 | Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration |
| Q35752001 | Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72 |
| Q37388933 | Clinical and pathological continuum of multisystem TDP-43 proteinopathies |
| Q34472281 | Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family |
| Q36534978 | Coexistence of Huntington's disease and amyotrophic lateral sclerosis: a clinicopathologic study |
| Q37833138 | Coexistence of TDP-43 and tau pathology in neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome). |
| Q36967985 | Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia |
| Q36860214 | Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies |
| Q54487815 | Cortical degeneration in frontotemporal lobar degeneration with TDP-43 proteinopathy caused by progranulin gene mutation. |
| Q36611403 | Corticospinal tract degeneration associated with TDP-43 type C pathology and semantic dementia |
| Q92060228 | Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation |
| Q36769877 | Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. |
| Q47351811 | Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons. |
| Q30574024 | Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species |
| Q42617513 | Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis |
| Q35776901 | Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations |
| Q38383420 | Distinct white matter injury associated with medial temporal lobe atrophy in Alzheimer's versus semantic dementia |
| Q36741538 | Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation |
| Q34030729 | Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease |
| Q34455613 | Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration? |
| Q34886007 | Eating and hypothalamus changes in behavioral-variant frontotemporal dementia |
| Q36734898 | Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis |
| Q37217962 | Epidemiological aspects of frontotemporal dementia. |
| Q34604146 | Evaluation of subcortical pathology and clinical correlations in FTLD-U subtypes |
| Q48335991 | Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration |
| Q93083717 | FTD spectrum: Neuroimaging across the FTD spectrum |
| Q33922335 | FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration |
| Q38392876 | Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations |
| Q48515203 | Frequency of progranulin mutations in a German cohort of 79 frontotemporal dementia patients |
| Q33830991 | Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration |
| Q48650516 | Fronto-temporal lobar degeneration: neuropathology in 60 cases |
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| Q28081198 | Frontotemporal dementia: a bridge between dementia and neuromuscular disease |
| Q37987142 | Frontotemporal dementia: implications for understanding Alzheimer disease |
| Q37217966 | Frontotemporal lobar degeneration: clinical and pathologic overview |
| Q35204586 | Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine |
| Q37451385 | Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. |
| Q35773678 | Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration |
| Q89438455 | Genetic Modifiers in Neurodegeneration |
| Q30503638 | Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration |
| Q38786774 | Genetics of FTLD: overview and what else we can expect from genetic studies |
| Q60521494 | Genotype–phenotype links in frontotemporal lobar degeneration |
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| Q34992164 | Hippocampal sclerosis in advanced age: clinical and pathological features. |
| Q35872213 | History, present, and progress of frontotemporal dementia in china: a systematic review |
| Q36107386 | Imaging signatures of molecular pathology in behavioral variant frontotemporal dementia |
| Q36397371 | Immunolocalization of TAR DNA-binding protein of 43 kDa (TDP-43) in mouse seminiferous epithelium |
| Q92267709 | LATE to the PART-y |
| Q36417377 | Laminar distribution of the pathological changes in sporadic frontotemporal lobar degeneration with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy: a quantitative study using polynomial curve fitting |
| Q35757342 | Longitudinal gray matter contraction in three variants of primary progressive aphasia: A tenser-based morphometry study |
| Q51679825 | Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis. |
| Q26768648 | Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine |
| Q37143159 | Molecular neuropathology of TDP-43 proteinopathies |
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| Q35075257 | Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy |
| Q37260852 | Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia |
| Q37302783 | Neurocognitive speed associates with frontotemporal lobar degeneration TDP-43 subtypes |
| Q38491219 | Neurodegeneration and sport |
| Q37980047 | Neuroimaging in frontotemporal lobar degeneration--predicting molecular pathology |
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| Q90234407 | Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology |
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| Q48529691 | Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium |
| Q37879961 | Neuropathological background of phenotypical variability in frontotemporal dementia |
| Q33694019 | Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis |
| Q47237309 | Neuropathology of frontotemporal lobar degeneration: a review |
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| Q35592875 | On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia |
| Q37221392 | Pallidonigral TDP-43 pathology in Perry syndrome |
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| Q38219206 | Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS. |
| Q47875646 | Pathologic Involvement of Glutamatergic Striatal Inputs From the Cortices in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis |
| Q34632269 | Pathological 43-kDa Transactivation Response DNA-Binding Protein in Older Adults With and Without Severe Mental Illness |
| Q38222195 | Pathology in primary progressive aphasia syndromes |
| Q39071493 | Pathology of Neurodegenerative Diseases |
| Q36075739 | Patterns of striatal degeneration in frontotemporal dementia |
| Q37171556 | Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. |
| Q37220481 | Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies |
| Q37688883 | Primary progressive aphasia: clinicopathological correlations |
| Q79573361 | Progranulin mutations in Dutch familial frontotemporal lobar degeneration |
| Q50074864 | Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients |
| Q36826623 | Progranulin: an emerging target for FTLD therapies |
| Q43153283 | Progressive anterior operculum syndrome due to FTLD-TDP: a clinico-pathological investigation |
| Q37485657 | Promoter DNA methylation regulates progranulin expression and is altered in FTLD. |
| Q37918720 | RNA-binding proteins with prion-like domains in ALS and FTLD-U. |
| Q48202306 | Reappraisal of TDP-43 pathology in FTLD-U subtypes |
| Q33830518 | Recent insights into the molecular genetics of dementia |
| Q34602221 | Reference cluster normalization improves detection of frontotemporal lobar degeneration by means of FDG-PET. |
| Q37730008 | Role of progranulin as a biomarker for Alzheimer's disease |
| Q28732862 | Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia |
| Q38498391 | Semantic dementia with lower motor neuron disease showing FTLD-TDP type 3 pathology (sensu Mackenzie). |
| Q37895186 | Semantic dementia: a specific network-opathy |
| Q38246772 | Significance and limitation of the pathological classification of TDP-43 proteinopathy |
| Q33703433 | Sporadic corticobasal syndrome due to FTLD-TDP. |
| Q37621617 | Staging TDP-43 pathology in Alzheimer's disease |
| Q39995384 | Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations |
| Q37082139 | TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study |
| Q33941040 | TAR DNA-binding protein 43 in neurodegenerative disease |
| Q28294001 | TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia |
| Q37733168 | TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration |
| Q37576086 | TDP-43 and frontotemporal dementia |
| Q37179756 | TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease |
| Q34566756 | TDP-43 in aging and Alzheimer's disease - a review |
| Q35928153 | TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions |
| Q57306362 | TDP-43 in neurodegenerative disorders |
| Q48284829 | TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations |
| Q37039451 | TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis |
| Q34131994 | TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. |
| Q34455599 | TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia |
| Q30493749 | TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration |
| Q35448769 | TDP-43 variants of frontotemporal lobar degeneration |
| Q48244352 | TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions |
| Q37183193 | TDP-43: a novel neurodegenerative proteinopathy |
| Q91451096 | Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy |
| Q36115656 | Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease |
| Q30780758 | The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. |
| Q64054884 | The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD |
| Q36926070 | The genetics of frontotemporal lobar degeneration |
| Q37564674 | The molecular basis of frontotemporal dementia |
| Q36931728 | The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments |
| Q38493216 | The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene |
| Q38172839 | The neuropathology associated with repeat expansions in the C9ORF72 gene |
| Q35992776 | The non-fluent/agrammatic variant of primary progressive aphasia |
| Q33847532 | The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia |
| Q37425088 | Two distinct subtypes of right temporal variant frontotemporal dementia |
| Q37205729 | Update on recent molecular and genetic advances in frontotemporal lobar degeneration |
| Q30487226 | VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death |
| Q33978879 | Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration |
| Q35275364 | White matter damage in primary progressive aphasias: a diffusion tensor tractography study. |
| Q38480715 | Whole-brain white matter disruption in semantic and nonfluent variants of primary progressive aphasia |
| Q35752114 | Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease |
| Q42499857 | Widespread neuronal and glial hyperphosphorylated tau deposition in ALS with cognitive impairment. |
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| Q58477808 | p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS |
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