Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus

scientific article published on 9 September 2011

Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.NEUROBIOLAGING.2011.07.015
P932PMC publication ID3237944
P698PubMed publication ID21907460
P5875ResearchGate publication ID51638936

P50authorRuth M. BarrientosQ40382506
Jared T AhrendsenQ60998029
P2093author name stringSteven F Maier
Susan L Patterson
Timothy R Chapman
Jennifer M Hoover
P2860cites workSenescent synapses and hippocampal circuit dynamicsQ37673419
Neural mechanisms of ageing and cognitive declineQ37718609
Cytokines and neuronal channels: a molecular basis for age-related decline of neuronal function?Q37792342
Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formationQ40906890
Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulationQ42442023
Mouse and rat BDNF gene structure and expression revisitedQ42772346
Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neuronsQ43264231
BDNF and trkB mRNA expression in the hippocampal formation of aging ratsQ43544870
BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's diseaseQ43727698
The exercise-induced expression of BDNF within the hippocampus varies across life-spanQ43996853
Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrusQ44333324
A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitroQ44406446
Acute cognitive impairment in elderly ED patients: etiologies and outcomesQ44519210
Brain-derived neurotrophic factor mRNA downregulation produced by social isolation is blocked by intrahippocampal interleukin-1 receptor antagonistQ47421203
Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promotersQ48149300
Regional changes in the expression of neurotrophic factors and their receptors following acute traumatic brain injury in the adult rat brain.Q48182292
Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.Q48342243
Activity-Dependent Dendritic Targeting of BDNF and TrkB mRNAs in Hippocampal NeuronsQ48567864
Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats.Q48753922
Differential effects of protein synthesis inhibition on the activity-dependent expression of BDNF transcripts: evidence for immediate-early gene responses from specific promotersQ48857420
Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N ratsQ48865924
Peripheral infection and aging interact to impair hippocampal memory consolidationQ48886448
Differential effects of everyday stress on the episodic memory test performances of young, mid-life, and older adultsQ50770861
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learningQ50987116
BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administrationQ50993547
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout miceQ52201421
The inhibitory effect of interleukin-1beta on long-term potentiation is coupled with increased activity of stress-activated protein kinasesQ62011079
Lipopolysaccharide Inhibits Long Term Potentiation in the Rat Dentate Gyrus by Activating Caspase-1Q62011083
Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damageQ71815680
Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathwayQ73704465
New insights into brain BDNF function in normal aging and Alzheimer diseaseQ22252335
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNFQ24292266
Neurotrophins and their receptors: a convergence point for many signalling pathwaysQ29616108
BDNF and activity-dependent synaptic modulationQ33820669
An epigenetic hypothesis of aging-related cognitive dysfunctionQ33868359
Susceptibility to Calcium Dysregulation during Brain AgingQ33868432
Age-related changes in Arc transcription and DNA methylation within the hippocampus.Q33925933
Prominent hippocampal CA3 gene expression profile in neurocognitive agingQ33938940
Synaptic correlates of increased cognitive vulnerability with aging: peripheral immune challenge and aging interact to disrupt theta-burst late-phase long-term potentiation in hippocampal area CA1Q33939742
Cytokine-induced sickness behaviour: mechanisms and implicationsQ34114821
Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF).Q34115778
The neurotrophin hypothesis for synaptic plasticity.Q34117599
Regulation of late-phase LTP and long-term memory in normal and aging hippocampus: role of secreted proteins tPA and BDNF.Q34367367
The yin and yang of neurotrophin actionQ34439423
BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesisQ34442760
Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent MechanismQ34467554
Gene expression in the hippocampus: Regionally specific effects of aging and caloric restrictionQ34544188
A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibitionQ34889693
Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomesQ34910043
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learningQ34931098
Cognitive function after anaesthesia in the elderlyQ35158880
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memoryQ35851895
Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampusQ36126368
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neuronsQ36856173
From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and functionQ37279404
Biological functions of activity-dependent transcription revealedQ37336125
Characterization of the sickness response in young and aging rats following E. coli infectionQ37437808
P4510describes a project that usesImageQuantQ112270642
P433issue4
P304page(s)832.e1-14
P577publication date2011-09-09
P1433published inNeurobiology of AgingQ7002141
P1476titleAging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus
P478volume33

Reverse relations

cites work (P2860)
Q3406741917β-Estradiol regulates histone alterations associated with memory consolidation and increases Bdnf promoter acetylation in middle-aged female mice.
Q38645679Age and Chronicity of Administration Dramatically Influenced the Impact of Low Dose Paraquat Exposure on Behavior and Hypothalamic-Pituitary-Adrenal Activity
Q55311979Aging and an Immune Challenge Interact to Produce Prolonged, but Not Permanent, Reductions in Hippocampal L-LTP and mBDNF in a Rodent Model with Features of Delirium.
Q38620528Animal inflammation-based models of depression and their application to drug discovery.
Q38693724BDNF in sleep, insomnia, and sleep deprivation
Q37300518BDNF transcripts, proBDNF and proNGF, in the cortex and hippocampus throughout the life span of the rat
Q38769563Brain-Derived Neurotrophic Factor Expression in Individuals With Schizophrenia and Healthy Aging: Testing the Accelerated Aging Hypothesis of Schizophrenia
Q36943048Brain-Derived Neurotrophic Factor-Dependent Synaptic Plasticity Is Suppressed by Interleukin-1β via p38 Mitogen-Activated Protein Kinase
Q92799438Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain
Q37310546Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets
Q27006784Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity
Q50074937Circulating biomarkers in extremely preterm infants associated with ultrasound indicators of brain damage.
Q38761126Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research
Q35819175Diet-induced changes in brain structure and behavior in old gerbils
Q37973295Dysfunctional Nucleus Tractus Solitarius: Its Crucial Role in Promoting Neuropathogentic Cascade of Alzheimer’s Dementia—A Novel Hypothesis
Q54978077Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice.
Q35570017Effects of senescence on the expression of BDNF and TrkB receptor in the lateral geniculate nucleus of cats
Q45288581Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.
Q40469920Forebrain-Specific Transgene Rescue of 11β-HSD1 Associates with Impaired Spatial Memory and Reduced Hippocampal Brain-Derived Neurotrophic Factor mRNA Levels in Aged 11β-HSD1 Deficient Mice.
Q35137555Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia
Q38673653High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory
Q47251487Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment
Q54997614Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
Q26853611Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity
Q35965078Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice
Q35143317Is schizophrenia a neurodegenerative disease? Evidence from age-related decline of brain-derived neurotrophic factor in the brains of schizophrenia patients and matched nonpsychiatric controls
Q36678453Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation
Q28388537Neuroinflammation in the normal aging hippocampus
Q47965615Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development.
Q28771399PKC activation during training restores mushroom spine synapses and memory in the aged rat
Q93061615PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease
Q38049597Review: Microglia of the aged brain: primed to be activated and resistant to regulation
Q47194743Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair
Q30839290S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice.
Q34364266Sign-tracking to an appetitive cue predicts incubation of conditioned fear in rats
Q35682264Stochastic fluctuations in gene expression in aging hippocampal neurons could be exacerbated by traumatic brain injury

Search more.