Suppression of Human T Cell Proliferation Mediated by the Cathepsin B Inhibitor, z-FA-FMK Is Due to Oxidative Stress

scientific article published on 27 April 2015

Suppression of Human T Cell Proliferation Mediated by the Cathepsin B Inhibitor, z-FA-FMK Is Due to Oxidative Stress is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1023711R
P356DOI10.1371/JOURNAL.PONE.0123711
P932PMC publication ID4411069
P698PubMed publication ID25915766
P5875ResearchGate publication ID276134000

P2093author name stringSek Chuen Chow
Tanuja Rajah
P2860cites workPleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiencyQ28204372
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The cathepsin B inhibitor, z-FA-FMK, inhibits human T cell proliferation in vitro and modulates host response to pneumococcal infection in vivo.Q34563246
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The cathepsin B inhibitor, z-FA-CMK is toxic and readily induced cell death in human T lymphocytesQ39112445
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The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharideQ40814428
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Depletion of tissue glutathione with diethyl maleate enhances hyperbaric oxygen toxicityQ41233536
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EPOX inhibits angiogenesis by degradation of Mcl-1 through ERK inactivation.Q45923782
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Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity.Q46630714
Glutathione depletion by buthionine sulfoximine induces DNA deletions in miceQ46703171
The inhibition of human T cell proliferation by the caspase inhibitor z-VAD-FMK is mediated through oxidative stressQ46901326
Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activationQ47683889
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Interaction with XIAP prevents full caspase-3/-7 activation in proliferating human T lymphocytes.Q53473485
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Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseasesQ68760971
Modulation of intracellular glutathione concentrations alters lymphocyte activation and proliferationQ69057009
Glutathione Depletion in Human T Lymphocytes: Analysis of Activation-Associated Gene Expression and the Stress ResponseQ71983524
Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritisQ72296654
63 Inactivation of trypsin-like enzymes with peptides of arginine chloromethyl ketoneQ72754703
Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytesQ77367648
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)e0123711
P577publication date2015-04-27
P1433published inPLOS OneQ564954
P1476titleSuppression of Human T Cell Proliferation Mediated by the Cathepsin B Inhibitor, z-FA-FMK Is Due to Oxidative Stress
P478volume10

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cites work (P2860)
Q51132166Cathepsin B-Specific Metabolic Precursor for In Vivo Tumor-Specific Fluorescence Imaging.
Q33761332Predicting disease onset in clinically healthy people
Q49184973Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro.
Q46315114The aminopeptidase inhibitor, z-L-CMK, is toxic and induces cell death in Jurkat T cells through oxidative stress

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