JAK2(V617F): Prevalence in a large Chinese hospital population

scientific article published on 31 August 2006

JAK2(V617F): Prevalence in a large Chinese hospital population is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2006-03-009472
P932PMC publication ID1785080
P698PubMed publication ID16946305
P5875ResearchGate publication ID6843222

P50authorShu XingQ42774641
P2093author name stringJian Luo
Qi Zhang
Xueqi Fu
Qingshan Li
Zhizhuang Joe Zhao
Sanford B Krantz
Xuesong Xu
P2860cites workThe JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromesQ35848032
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant modelQ35849674
Role of tyrosine kinases and phosphatases in polycythemia vera.Q36279243
Detection of the single hotspot mutation in the JH2 pseudokinase domain of Janus kinase 2 in bone marrow trephine biopsies derived from chronic myeloproliferative disordersQ38437889
Methods for the detection of the JAK2 V617F mutation in human myeloproliferative disordersQ40347739
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemiaQ42182981
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor betaQ44104227
Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disordersQ46513376
The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disordersQ46735262
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemiaQ27266125
Oncogenic kinase signallingQ28189493
Current opinion in essential thrombocythemia: pathogenesis, diagnosis, and managementQ28191835
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia veraQ28241887
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2Q28243103
Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemiaQ28250886
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemiaQ28253771
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemiaQ29547900
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosisQ29614337
A gain-of-function mutation of JAK2 in myeloproliferative disordersQ29618851
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disordersQ29618853
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis.Q33371084
Identification of an acquired JAK2 mutation in polycythemia veraQ33947635
Polycythemia vera: myths, mechanisms, and managementQ34977300
Jak family of kinases in cancerQ35186465
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)339-342
P577publication date2006-08-31
P1433published inBloodQ885070
P1476titleJAK2(V617F): Prevalence in a large Chinese hospital population
P478volume109

Reverse relations

cites work (P2860)
Q37377284A progenitor cell origin of myeloid malignancies
Q42062133Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories
Q36306467Budd-Chiari Syndrome in a Patient with JAK-2 V617F and Factor V G1691A Mutations
Q36248587Characterization of a highly effective protein substrate for analysis of JAK2(V617F) Activity
Q51781540Clinical performance of JAK2 V617F mutation detection assays in a molecular diagnostics laboratory: evaluation of screening and quantitation methods.
Q96230224Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking
Q37284926Comparison of JAK2V617F mutation assessment employing different molecular diagnostic techniques
Q36374813Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders
Q33813824Detection of exon 12 Mutations in the JAK2 gene: enhanced analytical sensitivity using clamped PCR and nucleotide sequencing
Q35521645Development of a highly sensitive method for detection of JAK2V617F
Q44345261Diagnostic value of JAK2 V617F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population
Q24685474Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth
Q37250169Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM090
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Q39309957Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients
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