Structure-based enzyme engineering and its impact on in vitro glycorandomization.

scientific article published on January 2004

Structure-based enzyme engineering and its impact on in vitro glycorandomization. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/CBIC.200300620
P698PubMed publication ID14695508

P50authorJon S ThorsonQ41112392
P2093author name stringDimitar B Nikolov
William A Barton
Christoph Albermann
Dirk Hoffmeister
P2860cites workStructure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed formsQ27618381
Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamilyQ27619240
The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA)Q27628928
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomizationQ27632060
Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibioticsQ27633560
Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferaseQ27636040
Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineeringQ27639760
Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsAQ27640213
Formation of unusual sugars: mechanistic studies and biosynthetic applicationsQ28202326
Purification, characterization and HPLC assay of Salmonella glucose-1-phosphate thymidylyl-transferase from the cloned rfbA geneQ28490048
Glycosyltransferases in plant natural product synthesis: characterization of a supergene family.Q30321076
Two sequence elements of glycosyltransferases involved in urdamycin biosynthesis are responsible for substrate specificity and enzymatic activity.Q30328318
Directed enzyme evolutionQ30699657
Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificityQ30829563
Cloning and expression of a gene encoding N-glycosyltransferase (ngt) from Saccarothrix aerocolonigenes ATCC39243.Q30882269
Milestones in directed enzyme evolution.Q31120721
The biosynthesis of indolocarbazoles in a heterologous E. coli host.Q31124008
Glycosyltransferase structure and mechanismQ34066499
Plant glycosyltransferasesQ34225190
Glycosyltransferases in secondary plant metabolism: tranquilizers and stimulant controllersQ34317234
Glycosides in medicine: "The role of glycosidic residue in biological activity".Q34372899
Vancomycin, teicoplanin, and ramoplanin: synthetic and mechanistic studiesQ34386815
Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensisQ34422819
Remarkable structural similarities between diverse glycosyltransferasesQ35033333
The role of carbohydrates in biologically active natural productsQ41468708
Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides.Q43569384
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivativesQ43975942
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptidesQ44260076
Application of the nucleotidylyltransferase Ep toward the chemoenzymatic synthesis of dTDP-desosamine analoguesQ44436764
Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moietyQ73816749
Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl DerivativesQ95777475
Biosynthesis of Desosamine: Construction of a New Methymycin/Neomethymycin Analogue by Deletion of a Desosamine Biosynthetic GeneQ105033886
P433issue1
P921main subjectEnzyme engineeringQ835607
P304page(s)16-25
P577publication date2004-01-01
P1433published inChemBioChemQ634395
P1476titleStructure-based enzyme engineering and its impact on in vitro glycorandomization
P478volume5

Reverse relations

cites work (P2860)
Q36742059A comparison of sugar indicators enables a universal high-throughput sugar-1-phosphate nucleotidyltransferase assay
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