D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions

scientific article published on 24 November 2011

D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2011.07559.X
P932PMC publication ID3240708
P698PubMed publication ID22035199
P5875ResearchGate publication ID51754638

P2093author name stringMeenakshi Sharma
Abraham Kovoor
Jeremy Celver
P2860cites workDopamine receptors: from structure to functionQ24336139
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Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5Q24670878
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Distribution of RGS9-2 in neurons of the mouse striatum.Q40322043
Morphine activates opioid receptors without causing their rapid internalizationQ41175884
Effects of ionic and nonionic detergents on antigen-antibody reactionsQ41331131
A fifth member of the mammalian G-protein beta-subunit family. Expression in brain and activation of the beta 2 isotype of phospholipase C.Q41443050
Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins.Q41716772
RGS9 modulates dopamine signaling in the basal gangliaQ42443389
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RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.Q46832204
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.Q46840630
Consistent with dopamine supersensitivity, RGS9 expression is diminished in the amphetamine-treated animal model of schizophrenia and in postmortem schizophrenia brainQ48264084
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Mutational analysis of the Asn residue essential for RGS protein binding to G-proteinsQ74326003
DEP domains: More than just membrane anchorsQ79163974
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 familyQ81230034
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysisQ27736041
DEP-domain-mediated regulation of GPCR signaling responses.Q27930240
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A novel form of the G protein β Subunit Gβ5 is specifically expressed in the vertebrate retinaQ28296250
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RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneuronsQ28578625
Brain-specific RGS9-2 is localized to the nucleus via its unique proline-rich domainQ28580061
Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptorsQ28580254
Lipid rafts as a membrane-organizing principleQ29615727
Mammalian RGS proteins: multifunctional regulators of cellular signalling.Q30354302
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Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytesQ31520490
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?Q33211909
Proteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysisQ33932130
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Opioid receptorsQ34326054
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D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.Q34397299
Psychosis pathways converge via D2high dopamine receptorsQ34540180
Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by defaultQ34990345
A novel kind of G protein heterodimer: the G beta5-RGS complexQ35140422
Understanding antipsychotic "atypicality": a clinical and pharmacological moving targetQ35200831
Lipid rafts: heterogeneity on the high seasQ35602692
The dopamine D2 receptor: new surprises from an old friendQ36213277
Lipid rafts, detergent-resistant membranes, and raft targeting signalsQ36659985
Organization of the functions and components of the endoplasmic reticulumQ36700292
A proteomic approach to receptor signaling: molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex.Q36896270
G-protein-coupled receptor-signaling components in membrane raft and caveolae microdomains.Q37168203
D2 receptor partial agonists: treatment of CNS disorders of dopamine functionQ37239954
Domains in biological membranesQ37562159
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)56-69
P577publication date2011-11-24
P1433published inJournal of NeurochemistryQ6295643
P1476titleD(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions
P478volume120

Reverse relations

cites work (P2860)
Q30409324Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease
Q30451613D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms
Q33854287Desensitized D2 autoreceptors are resistant to trafficking
Q28542580G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization
Q35117457Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease
Q36812337Plasma membrane compartmentalization of D2 dopamine receptors
Q60954719RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models
Q90322691Regulation of monoamine transporters and receptors by lipid microdomains: implications for depression
Q28547376Role for Rab10 in Methamphetamine-Induced Behavior

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