Influence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients

scientific article published on April 2015

Influence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S40262-014-0213-7
P932PMC publication ID4435744
P698PubMed publication ID25511793
P5875ResearchGate publication ID269578566

P2093author name stringGregory E Wilding
Rocco C Venuto
Kimberly Clark
Kathleen M Tornatore
Calvin J Meaney
Karen Shin
Aijaz Gundroo
Shirley S Chang
Gerald J Fetterly
Joshua Prey
Louise M Cooper
Vanessa Gray
P2860cites workA more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study GroupQ29614889
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Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) RegistryQ34365272
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Mycophenolic Acid Pharmacodynamics and Pharmacokinetics Provide a Basis for Rational Monitoring StrategiesQ35129548
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Genetic and nongenetic determinants of between-patient variability in the pharmacokinetics of mycophenolic acidQ36274069
Ethnic or racial differences revisited: impact of dosage regimen and dosage form on pharmacokinetics and pharmacodynamicsQ36597641
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Impact of gastrointestinal-related side effects on mycophenolate mofetil dosing and potential therapeutic strategiesQ37272044
New insights into the pharmacokinetics and pharmacodynamics of the calcineurin inhibitors and mycophenolic acid: possible consequences for therapeutic drug monitoring in solid organ transplantationQ37523152
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Pharmacology and toxicology of mycophenolate in organ transplant recipients: an updateQ38208983
Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and glutathione conjugationQ39587524
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Enteric-coated mycophenolate sodium.Q42925114
Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipientsQ43463833
Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acidQ43569296
In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetilQ43760215
Economic impact and long-term graft outcomes of mycophenolate mofetil dosage modifications following gastrointestinal complications in renal transplant recipientsQ44316340
Race and drug formulation influence on mycophenolic acid pharmacokinetics in stable renal transplant recipientsQ44447188
Equivalent pharmacokinetics of mycophenolate mofetil in African-American and Caucasian male and female stable renal allograft recipientsQ44663050
Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in ratsQ44772834
Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in stable renal transplant patientsQ44789623
The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudyQ46055999
Comparing mycophenolate mofetil regimens for de novo renal transplant recipients: the fixed-dose concentration-controlled trialQ46301570
Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.Q46427135
Differential effects of cyclosporine and tacrolimus on mycophenolate pharmacokinetics in patients with impaired kidney functionQ46512740
Population pharmacokinetics of mycophenolic acid during the first week after renal transplantationQ46622999
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Reduced exposure to calcineurin inhibitors in renal transplantationQ46840533
Explaining variability in mycophenolic acid exposure to optimize mycophenolate mofetil dosing: a population pharmacokinetic meta-analysis of mycophenolic acid in renal transplant recipients.Q46923376
Simultaneous determination of cortisol, dexamethasone, methylprednisolone, prednisone, prednisolone, mycophenolic acid and mycophenolic acid glucuronide in human plasma utilizing liquid chromatography-tandem mass spectrometryQ46956941
Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantationQ46972643
Gastrointestinal quality of life improvement of renal transplant recipients converted from mycophenolate mofetil to enteric-coated mycophenolate sodium drugs or agents: mycophenolate mofetil and enteric-coated mycophenolate sodiumQ48629550
Organ Procurement and Transplantation Network and Scientific Registry of Transplant Recipients 2010 Data ReportQ60307956
RS-61443--a phase I clinical trial and pilot rescue studyQ67513704
Mycophenolic acid area under the curve values in African American and Caucasian renal transplant patients are comparableQ73927459
Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidationQ74528702
The pharmacokinetics of a single oral dose of mycophenolate mofetil in patients with varying degrees of renal functionQ74662793
Mycophenolate mofetil in renal transplantation: 3-year results from the placebo-controlled trial. European Mycophenolate Mofetil Cooperative Study GroupQ78164651
Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipientsQ79294815
Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipientsQ79428999
Pharmacokinetic and pharmacodynamic comparison of enteric-coated mycophenolate sodium and mycophenolate mofetil in maintenance renal transplant patientsQ80054548
Is this the drug or dose for you? Impact and consideration of ethnic factors in global drug development, regulatory review, and clinical practiceQ81803899
Mycophenolic acid pharmacokinetics during maintenance immunosuppression in African American and Caucasian renal transplant recipientsQ83136486
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
P304page(s)423-434
P577publication date2015-04-01
P1433published inClinical PharmacokineticsQ5133788
P1476titleInfluence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients
P478volume54

Reverse relations

cites work (P2860)
Q28074348An Update on Treatment and Management of Pediatric Systemic Lupus Erythematosus
Q92889788Different Routes of Proton Pumps Inhibitors Co-Administration have Significant Impact on Mycophenolate Acid (MPA) Serum Levels in Heart Transplant Recipients
Q53126891Pharmacokinetic Variability of Mycophenolic Acid in Pediatric and Adult Patients With Hematopoietic Stem Cell Transplantation.
Q90497577Sex and the kidneys: current understanding and research opportunities
Q38750337Sex differences in transplantation
Q56380780The utility of trough mycophenolic acid levels for the management of lupus nephritis

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