| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1081/DMR-120026496 |
| P698 | PubMed publication ID | 14705864 |
| P2093 | author name string | Frank J Gonzalez | |
| P2860 | cites work | NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms | Q28142533 |
| Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects | Q28322217 | ||
| Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas | Q28343187 | ||
| Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene | Q28505619 | ||
| Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development | Q28507862 | ||
| Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice | Q28512092 | ||
| Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension | Q28575908 | ||
| Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor | Q28589085 | ||
| Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2 | Q28591646 | ||
| Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation | Q29615439 | ||
| Functional Cyp2e1 is required for substantial in vivo formation of 2,5-hexanedione from n-hexane in the mouse | Q32000931 | ||
| Meat, metabolic genotypes and risk for colorectal cancer. | Q33709507 | ||
| The genetics and genomics of cancer | Q34180336 | ||
| Glutathione-S-transferase family of enzymes. | Q34355370 | ||
| Pharmacogenomics: the inherited basis for interindividual differences in drug response | Q34433440 | ||
| Genetic basis of glaucoma | Q34553228 | ||
| Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor | Q34977415 | ||
| The relationship between polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer | Q35035614 | ||
| Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. | Q35823922 | ||
| Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases | Q36068630 | ||
| CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity | Q40671039 | ||
| Recent advances in molecular genetics of glaucomas | Q41595926 | ||
| Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery | Q42481869 | ||
| NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin | Q43693218 | ||
| 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine | Q44002334 | ||
| Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice | Q44184640 | ||
| Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems | Q44279157 | ||
| Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6. | Q44346889 | ||
| Modification of ocular defects in mouse developmental glaucoma models by tyrosinase | Q44353964 | ||
| Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity | Q44374579 | ||
| Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2. | Q44381289 | ||
| Expression of the Human CYP3A4 Gene in the Small Intestine of Transgenic Mice: In Vitro Metabolism and Pharmacokinetics of Midazolam | Q44403612 | ||
| Multiple CYP1B1 mutations and incomplete penetrance in an inbred population segregating primary congenital glaucoma suggest frequent de novo events and a dominant modifier locus. | Q52171299 | ||
| Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity. | Q52529689 | ||
| CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice. | Q53419496 | ||
| Role of CYP2E1 in the hepatotoxicity of acetaminophen | Q71142786 | ||
| Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice | Q73187910 | ||
| Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor | Q74032170 | ||
| Metabolism of methyl tert-butyl ether and other gasoline ethers in mouse liver microsomes lacking cytochrome P450 2E1 | Q74636443 | ||
| Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice | Q77409971 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 319-335 | |
| P577 | publication date | 2003-11-01 | |
| P1433 | published in | Drug Metabolism Reviews | Q5308857 |
| P1476 | title | Role of gene knockout and transgenic mice in the study of xenobiotic metabolism | |
| P478 | volume | 35 |
| Q31097755 | A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach |
| Q37652699 | CRISPR knockout rat cytochrome P450 3A1/2 model for advancing drug metabolism and pharmacokinetics research |
| Q39523252 | Current challenges and controversies in drug-induced liver injury. |
| Q34545343 | Cytochrome P450 and xenobiotic receptor humanized mice |
| Q36426794 | Cytochrome P450 pharmacogenetics and cancer. |
| Q34513706 | Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models |
| Q36497642 | Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse model |
| Q35889610 | Genetically modified mouse models for pharmacogenomic research |
| Q33742730 | Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice |
| Q36275152 | LC-MS-based metabolomics in drug metabolism |
| Q36300806 | New horizon of MDR1 (P-glycoprotein) study |
| Q50848251 | Polymorphic variation of CYP1A1 and CYP1B1 genes in a Haryana population. |
| Q90385746 | Polymorphism of xenobiotic metabolizing gene and susceptibility of epithelial ovarian cancer with reference to organochlorine pesticides exposure |
| Q34306783 | Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer |
| Q37864339 | Surgical and pharmacological animal models used in drug metabolism and pharmacokinetics |
| Q35688431 | The use of genetically modified mice in cancer risk assessment: challenges and limitations. |
| Q92493625 | Tyroxine Hydroxylase-Positive Neuronal Cell Population is Increased by Temporal Dioxin Exposure at Early Stage of Differentiation from Human Embryonic Stem Cells |
| Q35001430 | Urinary metabolite profiling reveals CYP1A2-mediated metabolism of NSC686288 (aminoflavone). |
| Q38090712 | Utilization of glutathione S-transferase Mu 1- and Theta 1-null mice as animal models for absorption, distribution, metabolism, excretion and toxicity studies |
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