MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs

scientific article published on 7 May 2015

MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1019396B
P356DOI10.1371/JOURNAL.PONE.0119396
P932PMC publication ID4423774
P698PubMed publication ID25950587
P5875ResearchGate publication ID276063925

P50authorZishuai WangQ59702672
P2093author name stringKui Li
Chuduan Wang
Xinhua Hou
Yalan Yang
Zhonglin Tang
Shiyun Zhu
Lijing Bai
Ruyi Liang
P2860cites workActivin A impairs insulin action in cardiomyocytes via up-regulation of miR-143Q24297012
miR-145 and miR-143 regulate smooth muscle cell fate and plasticityQ24311186
beta ig-h3: a transforming growth factor-beta-responsive gene encoding a secreted protein that inhibits cell attachment in vitro and suppresses the growth of CHO cells in nude miceQ24313409
The developmental miRNA profiles of zebrafish as determined by small RNA cloningQ24529122
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7Q24615529
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiationQ24650204
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesisQ24656947
Distinctive patterns of microRNA expression in primary muscular disordersQ24675407
miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart developmentQ27320478
Mesenchymal miR-21 regulates branching morphogenesis in murine submandibular gland in vitro.Q51889558
Inhibition of skeletal muscle satellite cell differentiation by transforming growth factor-betaQ68780408
TGF-beta induces the differentiation of bone marrow stem cells into immature cardiomyocytesQ80407884
miR-143: a novel regulator of MyoD expression in fast and slow muscles of Siniperca chuatsiQ87396557
MicroRNAs: small RNAs with a big role in gene regulationQ27860896
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
MEF2: a central regulator of diverse developmental programsQ28254625
MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesisQ28269041
Developmental expression patterns of Beta-ig (betaIG-H3) and its function as a cell adhesion proteinQ28510176
MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiationQ30426550
Muscle-specific microRNA miR-206 promotes muscle differentiationQ30441356
The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytesQ31004726
LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigsQ33287976
A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAsQ33870658
Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathwayQ33878064
Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fateQ34001922
Attenuation of p38-mediated miR-1/133 expression facilitates myoblast proliferation during the early stage of muscle regenerationQ34387916
MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migrationQ34426103
Discovery of MicroRNAs associated with myogenesis by deep sequencing of serial developmental skeletal muscles in pigsQ34533056
Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesisQ35096079
Role of TGF-β signaling in inherited and acquired myopathiesQ35166254
OLFML3 expression is decreased during prenatal muscle development and regulated by microRNA-155 in pigsQ35828544
A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survivalQ35921672
MicroRNA-148a promotes myogenic differentiation by targeting the ROCK1 geneQ36033204
MicroRNA-206: the skeletal muscle-specific myomiR.Q37125050
Differential expression of serum miR-126, miR-141 and miR-21 as novel biomarkers for early detection of liver metastasis in colorectal cancerQ37608685
Regulation of gene expression in vertebrate skeletal muscleQ37773029
Genetic regulation of skeletal muscle developmentQ37786674
Role of miR-21 and its signaling pathways in renal diseasesQ38191696
MIR-206 regulates connexin43 expression during skeletal muscle developmentQ39081907
Blockage of a miR-21/EGFR regulatory feedback loop augments anti-EGFR therapy in glioblastomasQ39099065
MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancerQ39100768
MiR-23a inhibits myogenic differentiation through down regulation of fast myosin heavy chain isoformsQ39318263
A novel target of microRNA-29, Ring1 and YY1-binding protein (Rybp), negatively regulates skeletal myogenesisQ39337764
Mammalian skeletal muscle fiber type transitionsQ41322798
Differential response of embryonic and fetal myoblasts to TGFβ: a possible regulatory mechanism of skeletal muscle histogenesisQ41674323
Muscle development in large and small pig fetusesQ42005778
FGF-4 signaling is involved in mir-206 expression in developing somites of chicken embryosQ44266153
MicroRNA-100 regulates neovascularization by suppression of mammalian target of rapamycin in endothelial and vascular smooth muscle cellsQ45002548
MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factorsQ45887164
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)e0119396
P577publication date2015-05-07
P1433published inPLOS OneQ564954
P1476titleMicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs
P478volume10

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cites work (P2860)
Q64924418Alteration in cardiac PI3K/Akt/mTOR and ERK signaling pathways with the use of growth hormone and swimming, and the roles of miR21 and miR133.
Q37550322Comparative analysis of DNA methylome and transcriptome of skeletal muscle in lean-, obese-, and mini-type pigs
Q38456495Comparison of skeletal muscle miRNA and mRNA profiles among three pig breeds
Q90266321Comprehensive Profiles of mRNAs and miRNAs Reveal Molecular Characteristics of Multiple Organ Physiologies and Development in Pigs
Q92712679Differentially Expressed MiRNAs and tRNA Genes Affect Host Homeostasis During Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infections in Young Pigs
Q39190427Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy
Q39315669Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy
Q64917567Genome-Wide Investigation and Functional Analysis of Sus scrofa RNA Editing Sites across Eleven Tissues.
Q42257887MiR-696 Regulates C2C12 Cell Proliferation and Differentiation by Targeting CNTFRα
Q50161677MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway
Q37675880Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation
Q39978119SMAD7, an antagonist of TGF-beta signaling, is a candidate of prenatal skeletal muscle development and weaning weight in pigs
Q89977097miR-9-5p Inhibits Skeletal Muscle Satellite Cell Proliferation and Differentiation by Targeting IGF2BP3 through the IGF2-PI3K/Akt Signaling Pathway

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