Selectin ligands

scientific article published on August 1994

Selectin ligands is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P819ADS bibcode1994PNAS...91.7390V
P356DOI10.1073/PNAS.91.16.7390
P932PMC publication ID44407
P698PubMed publication ID7519775
P5875ResearchGate publication ID15678882

P2093author name stringVarki A
P2860cites workHigher-affinity oligosaccharide ligands for E-selectinQ24292848
Expression cloning of a functional glycoprotein ligand for P-selectinQ24304912
Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesionQ24336308
SelectinsQ24602099
A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin AQ24643787
Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical studyQ72226978
Involvement of sialic acid on endothelial cells in organ-specific lymphocyte recirculationQ93561918
A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesionQ24673642
Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domainsQ27729350
An endothelial ligand for L-selectin is a novel mucin-like moleculeQ28187110
Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milkQ28261440
Sulfated Glycolipids Are Ligands for a Lymphocyte Homing Receptor, L-Selectin (LECAM-1), Binding Epitope in Sulfated Sugar ChainQ28581968
P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesionQ28756449
Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiencyQ29028780
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversityQ29617967
PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)Q30826588
ELFT: a gene that directs the expression of an ELAM-1 ligandQ33259321
Sialyl Lewisx-containing oligosaccharide attenuates myocardial reperfusion injury in catsQ34132844
Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venulesQ34138342
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancerQ34171030
A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous systemQ34211700
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptorsQ34236758
Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitroQ34237390
Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44, and CD45 by a novel glycoprotease from Pasteurella haemolyticaQ34248065
Biochemistry of carbohydrate-protein interactionQ35379152
Selectins: interpreters of cell-specific carbohydrate information during inflammationQ35532358
Enhanced interaction of L-selectin with the high endothelial venule ligand via selectively oxidized sialic acidsQ36088463
The HNK-1 reactive sulfoglucuronyl glycolipids are ligands for L-selectin and P-selectin but not E-selectin.Q36103740
Physiological and molecular mechanisms of lymphocyte homingQ36135230
Evolutionary conservation of tissue-specific lymphocyte-endothelial cell recognition mechanisms involved in lymphocyte homingQ36219697
Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodesQ36219735
A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venulesQ36223118
Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptorQ36224360
The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1Q36230719
Monospecific and common glycoprotein ligands for E- and P-selectin on myeloid cellsQ36234196
Protective effects of sialylated oligosaccharides in immune complex-induced acute lung injuryQ36362174
GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interactionQ36529172
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptorQ36529782
The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptorQ36530024
The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cellsQ36530308
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cellsQ36533177
The vascular E-selectin binds to the leukocyte integrins CD11/CD18Q41564558
Identification of a glycoprotein ligand for E-selectin on mouse myeloid cellsQ41564745
Molecular mechanisms underlying lymphocyte recirculation. III. Characterization of the LECAM-1 (L-selectin)-dependent adhesion pathway in ratsQ41572490
Neutrophils, monocytes, and lymphocytes bind to cytokine-activated kidney glomerular endothelial cells through L-selectin (LAM-1) in vitroQ41601354
Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditionsQ41619814
P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.Q41620101
Comparison of L-selectin and E-selectin ligand specificities: the L-selectin can bind the E-selectin ligands sialyl Le(x) and sialyl Le(a)Q41627980
Recombinant E-selectin-protein mediates tumor cell adhesion via sialyl-Le(a) and sialyl-Le(x)Q41640023
Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cellsQ41640027
CD62/P-selectin binding sites for myeloid cells and sulfatides are overlappingQ41660720
CD62/P-selectin recognition of myeloid and tumor cell sulfatidesQ41661588
Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitroQ41672543
ELAM-1 is an adhesion molecule for skin-homing T cellsQ41694765
ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le xQ41714445
The complement binding-like domains of the murine homing receptor facilitate lectin activityQ41899904
Phosphorylation of surface E‐selectin and the effect of soluble ligand (Sialyl Lewisx) on the half‐life of E‐selectinQ41938987
Bovine gamma/delta T cells bind E-selectin via a novel glycoprotein receptor: first characterization of a lymphocyte/E-selectin interaction in an animal modelQ42147588
Species differences in the expression of carbohydrate differentiation antigens on mammalian blood cells revealed by immunofluorescence with monoclonal antibodiesQ42243924
Binding of L-Selectin to the Vascular Sialomucin CD34Q42805662
Identification of an E-selectin region critical for carbohydrate recognition and cell adhesionQ43108496
Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectinQ44187789
Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity.Q45148165
Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated plateletsQ46065245
L-selectin-mediated lymphocyte rolling on MAdCAM-1.Q46407093
P-selectin (CD62) binds to subpopulations of human memory T lymphocytes and natural killer cellsQ52073381
Activation-independent binding of human memory T cells to adhesion molecule ELAM-1.Q52100397
Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo.Q53029393
Protective effects of oligosaccharides in P-selectin-dependent lung injuryQ59060638
The glycoprotease of Pasteurella haemolytica A1 eliminates binding of myeloid cells to P-selectin but not to E-selectinQ67464443
Multi-recognition capability of E-selectin in a dynamic flow system, as evidenced by differential effects of sialidases and anti-carbohydrate antibodies on selectin-mediated cell adhesion at low vs. high wall shear stress: A preliminary noteQ67466940
Role of ELAM-1 in adhesion of monocytes to activated human endothelial cellsQ67531916
Evidence for endocytosis of E-selectin in human endothelial cellsQ67543295
GMP-140 binding to neutrophils is inhibited by sulfated glycansQ67684661
Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1Q67689512
Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesionQ67701303
The ligand recognized by ELAM-1 on HL60 cells is not carried by N-linked oligosaccharidesQ67705823
Reactivity of mucin-specific lectin from Sambucus sieboldiana with simple sugars, normal mucins and tumor-associated mucins. Comparison with other lectinsQ68270946
Structural study of the sugar chains of human leukocyte cell adhesion molecules CD11/CD18Q68292370
Characterization of human platelet GMP-140 as a heparin-binding proteinQ69116662
Structure and dynamics of mucin-like glycopeptides. Examination of peptide chain expansion and peptide-carbohydrate interactions by stochastic dynamics simulationsQ70597059
Differential expression of an E-selectin ligand (SLex) by two Chinese hamster ovary cell lines transfected with the same alpha (1,3)-fucosyltransferase gene (ELFT)Q71606780
Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificitiesQ71612632
Characterization of the E-selectin ligand on NK cellsQ71616366
Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endotheliumQ72067065
Interaction of P-selectin (CD62) and its cellular ligand: Analysis of critical residuesQ72074429
L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venulesQ72095769
A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cellsQ72101190
Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell linesQ72101794
Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injuryQ36674634
E-selectin-dependent adhesion efficiency of colonic carcinoma cells is increased by genetic manipulation of their cell surface lysosomal membrane glycoprotein-1 expression levelsQ36696099
Proteoglycans: structures and interactionsQ37285263
Carbohydrate ligands for endothelial-leukocyte adhesion molecule 1.Q37396249
Adhesion protein GMP140 inhibits superoxide anion release by human neutrophilsQ37441993
CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.Q37548676
Human eosinophil adherence to vascular endothelium mediated by binding to vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule 1Q37583010
Structural requirements for the carbohydrate ligand of E-selectinQ37626152
Why are proteins O-glycosylated?Q37951273
Consensus repeat domains of E-selectin enhance ligand bindingQ38311248
Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin.Q38311976
Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammationQ38314015
Structure-function studies on selectin carbohydrate ligands. Modifications to fucose, sialic acid and sulphate as a sialic acid replacementQ38314040
Rotaviruses preferentially bind O-linked sialylglycoconjugates and sialomucinsQ38315491
Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectinQ38317579
Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharidesQ38318413
High affinity binding of the leucocyte adhesion molecule L-selectin to 3'-sulphated-Le(a) and -Le(x) oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharidesQ38325258
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoproteinQ38325798
Further characterization of the interaction between L-selectin and its endothelial ligandsQ38327148
Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin densityQ38327660
CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytokine-activated endothelial cellsQ38327880
The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharideQ38329123
Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Lea and sialosyl-Lex, and sulfated glycans modulate this bindingQ38331669
The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140.Q38333447
A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1Q38333891
Recognition by Elam-1 of the Sialyl-Le x Determinant on Myeloid and Tumor CellsQ38338272
ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNAQ38338410
Oligosaccharide-protein interactions: a three-dimensional viewQ38345532
Lymphocyte homingQ38607582
Adhesion molecules controlling lymphocyte migrationQ38608814
Zona pellucida glycoproteinsQ39532120
Sulfated glycolipids and cell adhesionQ39554324
Selectins.Q40388550
Cell surface lectins in the immune systemQ40491314
Transport and sorting of membrane lipidsQ40788820
In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromesQ41021858
Calcium-Dependent Heparin-Like Ligands For L-Selectin in Nonlymphoid Endothelial CellsQ41541458
L-selectin mediates neutrophil rolling in inflamed venules through sialyl LewisX-dependent and -independent recognition pathways.Q41546428
P433issue16
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)7390-7397
P577publication date1994-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSelectin ligands
P478volume91

Reverse relations

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Q35679738Glycosylation defining cancer cell motility and invasiveness
Q35873312Glycosynapses: microdomains controlling carbohydrate-dependent cell adhesion and signaling
Q37623994Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility
Q40582925Gold glyconanoparticles as new tools in antiadhesive therapy.
Q37600859Guillain-Barré syndrome: update on immunobiology and treatment
Q36205161HECA-452 is a non-function blocking antibody for isolated sialyl Lewis x adhesion to endothelial expressed E-selectin under flow conditions
Q43942998HMG-CoA reductase inhibitor cerivastatin prolonged rat cardiac allograft survival by blocking intercellular signals
Q33971971Helminth C-type lectins and host-parasite interactions
Q24630993Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
Q77324114Heparin and enoxaparin enhance endotoxin-induced tumor necrosis factor-alpha production in human monocytes
Q33637649Heparin in inflammation: potential therapeutic applications beyond anticoagulation.
Q24552437Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
Q35030190Heparin-protein interactions
Q42081647Heterogeneity in Lewis-X and sialyl-Lewis-X antigen expression on monocytes in whole blood: relation to stimulus-induced oxidative burst
Q38297380Heterogeneous processing and zona pellucida binding activity of pig zonadhesin.
Q34000445Human intestinal M cells display the sialyl Lewis A antigen.
Q36332766Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activity
Q48424393Human umbilical cord blood cells protect against hypothalamic apoptosis and systemic inflammation response during heatstroke in rats
Q50475357Human umbilical cord blood-derived mesenchymal stromal cells display a novel interaction between P-selectin and galectin-1.
Q36366319Human vascular adhesion protein 1 (VAP-1) is a unique sialoglycoprotein that mediates carbohydrate-dependent binding of lymphocytes to endothelial cells
Q41296679Human α(1,3/1,4)-Fucosyltransferases Discriminate between Different Oligosaccharide Acceptor Substrates through a Discrete Peptide Fragment
Q40226733Hydrophilic/Hydrophobic balance determines morphology of glycolipids with oligolactose headgroups
Q50129430Identification and characterization of a sialidase released by the salivary gland of the hematophagous insect Triatoma infestans.
Q40957934Identification and characterization of ligands for L-selectin in the kidney. I. Versican, a large chondroitin sulfate proteoglycan, is a ligand for L-selectin
Q28508025Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II
Q36154915Identification of OmpA-Like Protein of Tannerella forsythia as an O-Linked Glycoprotein and Its Binding Capability to Lectins
Q28201648Identification of a missense mutation (G329A;Arg(110)--> GLN) in the human FUT7 gene
Q42601858Identification of an alpha2,6-sialyltransferase induced early after lymphocyte activation
Q34159952Identification of nine alternatively spliced alpha2,3-sialyltransferase, ST3Gal IV, transcripts and analysis of their expression by RT-PCR and laser-induced fluorescent capillary electrophoresis (LIF-CE) in twenty-one human tissues
Q73661014Immunoelectron microscopic detection of tissue ganglioside antigens
Q33939364Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients
Q28370585In vitro alpha1-3 or alpha1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI
Q38323429In vivo ligand specificity of E-selectin binding to multivalent sialyl Lewisx N-linked oligosaccharides
Q31976378In vivo specificity of human alpha1,3/4-fucosyltransferases III-VII in the biosynthesis of LewisX and Sialyl LewisX motifs on complex-type N-glycans. Coexpression studies from bhk-21 cells together with human beta-trace protein
Q33569192In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell--endothelial cell interaction
Q44721520In-plane structures of synthetic oligolactose lipid monolayers--impact of saccharide chain length
Q30452853Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides
Q38336780Inhibition of L- and P-selectin by a rationally synthesized novel core 2-like branched structure containing GalNAc-Lewisx and Neu5Acalpha2-3Galbeta1-3GalNAc sequences
Q74614796Inhibition of P-selectin attenuates neutrophil-mediated myocardial dysfunction in isolated rat heart
Q28144119Inhibition of binding of E- and P-selectin to sialyl-Lewis X molecule suppresses the inflammatory response in hypersensitivity pneumonitis in mice
Q42840045Inhibition of colon carcinoma cell lung colony formation by a soluble form of E-selectin.
Q73895558Inhibition of neuraminidase with neuraminic acid C-glycosides
Q37116804Inhibitors of selectin functions in the treatment of inflammatory skin disorders.
Q35026807Inhibitory effect of locally administered heparin on leukocyte rolling and chemoattractant-induced firm adhesion in rat mesenteric venules in vivo
Q27628438Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1
Q42054912Interaction between complement proteins C5b-7 and erythrocyte membrane sialic acid
Q38301936Interaction of Bordetella adenylate cyclase toxin with complement receptor 3 involves multivalent glycan binding
Q35545087Intervention in endotoxin shock by sulfatide (I3SO3-GalCer) with a concomitant reduction in tumor necrosis factor alpha production
Q52955845Intravascular granulocyte aggregates caused by the selectin-binding carbohydrate fucoidin in pig kidneys.
Q38331679Introducing a C-interglycosidic bond in a biologically active pentasaccharide hardly affects its biological properties
Q24678900Isolated P-selectin glycoprotein ligand-1 dynamic adhesion to P- and E-selectin
Q28378349Isolation and characterization from porcine serum of a soluble sulfotransferase responsible for 6-O-sulfation of the galactose residue in 2'-fucosyllactose: implications in the synthesis of the ligand for L-selectin
Q35592093L-Selectin ligands in lymphoid tissues and models of inflammation
Q24681588L-selectin from human, but not from mouse neutrophils binds directly to E-selectin
Q40650139LDL activates signaling pathways leading to an increase in cytosolic free calcium and stimulation of CD11b expression in monocytes
Q52053045Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment.
Q41052131Lack of selectin-dependent adhesion in prostate cancer cells expressing sialyl Le(x).
Q85117347Lacto-N-fucopentaose III, a Pentasaccharide, Prolongs Heart Transplant Survival
Q41114739Leucocyte adhesion molecules in host defence against infection
Q27027232Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow
Q33819619Leukocyte-endothelial interactions in inflammation
Q73480231Lewis(x)-containing oligosaccharide attenuates schistosome egg antigen-induced immune depression in human schistosomiasis
Q34109076Loss of N-glycolylneuraminic acid in humans: Mechanisms, consequences, and implications for hominid evolution
Q50752339Lymphocyte binding to vascular endothelium in inflamed skin revisited: a central role for vascular adhesion protein-1 (VAP-1).
Q36150816Lymphocyte trafficking to inflamed skin--molecular mechanisms and implications for therapeutic target molecules
Q26774414Mass Spectrometry-Based N-Glycomics of Colorectal Cancer
Q30690412Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis.
Q35839224Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers
Q38309526Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody
Q38296772Modulation of E-selectin structure/function by metal ions. Studies on limited proteolysis and metal ion regeneration
Q41093687Molecular characterization of gp40, a mucin-type glycoprotein from the apical plasma membrane of Madin-Darby canine kidney cells (type I)
Q28611500Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells
Q28569588Molecular cloning of a developmentally regulated N-acetylgalactosamine alpha2,6-sialyltransferase specific for sialylated glycoconjugates
Q22009402Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids
Q73044548Molecular cloning of rat alpha1,3-fucosyltransferase IX (Fuc-TIX) and comparison of the expression of Fuc-TIV and Fuc-TIX genes during rat postnatal cerebellum development
Q41281578Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase.
Q28566036Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments
Q38293078Molecular dynamics simulations of alpha2 --> 8-linked disialoside: conformational analysis and implications for binding to proteins.
Q36254610Monocyte adhesion to activated aortic endothelium: role of L-selectin and heparan sulfate proteoglycans
Q28211394Mucin biosynthesis: epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line
Q28297724Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line
Q73202309Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis
Q38121746Mucins in pancreatic cancer and its microenvironment
Q34270155Multifarious roles of sialic acids in immunity
Q41052960Multiplex RT-PCR method for the analysis of the expression of human sialyltransferases: application to breast cancer cells.
Q28565889Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site
Q34088167N-glycolylneuraminic acid deficiency in humans
Q37131491Nanotechnology in the detection and control of microorganisms
Q91871996Neuraminidase-3 Is a Negative Regulator of LFA-1 Adhesion
Q37359036Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro
Q35764552Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions
Q38296729New sialyl Lewis(x) mimic containing an alpha-substituted beta(3)-amino acid spacer.
Q38301832Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X).
Q26784159Notable Aspects of Glycan-Protein Interactions
Q38349977Novel glycoproteins inhibiting the binding of colorectal cancer cells to E-selectin
Q38299897Novel mimics of sialyl Lewis X: design, synthesis and biological activity of a series of 2- and 3-malonate substituted galactoconjugates
Q77357803Overexpression of MUC1 reconfigures the binding properties of tumor cells
Q36618060Overexpression of alpha(1,3)-fucosyltransferase VII is sufficient for the acquisition of lung colonization phenotype in human lung adenocarcinoma HAL-24Luc cells
Q36237566P-selectin glycoprotein ligand 1 is a ligand for L-selectin on neutrophils, monocytes, and CD34+ hematopoietic progenitor cells
Q41295462P-selectin glycoprotein ligand-1 is the major counter-receptor for P-selectin on stimulated T cells and is widely distributed in non-functional form on many lymphocytic cells
Q36382391P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin
Q28268588P-selectin mediates metastatic progression through binding to sulfatides on tumor cells
Q36236268P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils
Q34265306P-selectin, carcinoma metastasis and heparin: novel mechanistic connections with therapeutic implications
Q77937139Panosialins, inhibitors of an alpha1,3-fucosyltransferase Fuc-TVII, suppress the expression of selectin ligands on U937 cells
Q38301935Partial characterization of the N-linked oligosaccharide structures on P-selectin glycoprotein ligand-1 (PSGL-1).
Q41594921Perspectives on the significance of altered glycosylation of glycoproteins in cancer
Q92012033Pharmaceutical Development and Safety Evaluation of a GMP-Grade Fucoidan for Molecular Diagnosis of Cardiovascular Diseases
Q41756606Pharmacological modulation of cell adhesion molecules
Q34056920Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin
Q27025494Polysaccharide nanosystems for future progress in cardiovascular pathologies
Q43537316Potential pro-inflammatory effects of soluble E-selectin upon neutrophil function
Q47967053Properties and pharmacokinetics of two humanized antibodies specific for L-selectin
Q27691803Protein-carbohydrate interactions as part of plant defense and animal immunity.
Q38294132Purification of cranin, a laminin binding membrane protein. Identity with dystroglycan and reassessment of its carbohydrate moieties
Q39999770Purified polysaccharide from Ginkgo biloba leaves inhibits P-selectin-mediated leucocyte adhesion and inflammation
Q33915643Quantifying rolling adhesion with a cell-free assay: E-selectin and its carbohydrate ligands
Q35130932Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of alpha1-->3 fucosyltransferase VII and newly cloned GlcNAcbeta:6-sulfotransferase cDNA.
Q48164549Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 Å Resolution.
Q33802771Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils
Q35004397Regulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes.
Q40540137Relations of the type and branch of surface N-glycans to cell adhesion, migration and integrin expressions
Q71825143Repression of the Lewis fucosyl transferase by retinoic acid increases apical sialosyl Lewisa secretion in colorectal carcinoma cultures
Q41868366Role of Streptococcus gordonii surface proteins SspA/SspB and Hsa in platelet function.
Q37080012Role of cell adhesion molecules and immune-cell migration in the initiation, onset and development of atherosclerosis
Q35043025Role of selectins on IgE-mediated skin reaction
Q39453175Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.
Q71481083Selectin ligands on human melanoma cells
Q41469716Selectin ligands, leukocyte trafficking, and fucosyltransferase genes
Q37362400Selectin ligands: will the real ones please stand up?
Q41594933Selectin-carbohydrate interactions during inflammation and metastasis
Q39886779Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas
Q30433441Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation
Q27314565Selectins mediate small cell lung cancer systemic metastasis
Q52014822Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or alpha(4)beta(7)-integrin at the lesions of autoimmune gastritis.
Q39272313Self-recognition of high-mannose type glycans mediating adhesion of embryonal fibroblasts.
Q35091575Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.
Q39918308Serum-free production of a chimeric E-selectin-IgG protein from 1 to 100 l scale: Repeated batch cultivation versus continuous spin filter perfusion
Q42435915Sialic acid differential expression in non-melanoma skin cancer biopsies
Q40912594Sialic acids in molecular and cellular interactions
Q26995291Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration
Q34201156Sialoadhesin binds preferentially to cells of the granulocytic lineage.
Q33290245Sialyl Lewis x expression in canine malignant mammary tumours: correlation with clinicopathological features and E-Cadherin expression.
Q71815157Sialyl LewisX carbohydrate is expressed differentially during avian lymphoid cell development
Q64970855Sialyl Lewisx-P-selectin cascade mediates tumor-mesothelial adhesion in ascitic fluid shear flow.
Q71762348Sialyl-Lewis x and Sialyl-Lewis a are associated with MUC1 in human endometrium
Q36237657Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions
Q53965212Solution structure of a Lewis(x) analogue by off-resonance 1H NMR spectroscopy without use of an internal distance reference.
Q50428606Stereoselective Construction of β-Mannopyranosides by Anomeric O-Alkylation: Synthesis of the Trisaccharide Core of N-linked Glycans
Q57559274Strong and specific interaction of ultra small superparamagnetic iron oxide nanoparticles and human activated platelets mediated by fucoidan coating
Q28291747Structural Analysis of the Oligosaccharides Derived from Glycodelin, a Human Glycoprotein with Potent Immunosuppressive and Contraceptive Activities
Q40933396Structural and enzymatic characterization of human recombinant GDP-D-mannose-4,6-dehydratase.
Q30849070Structural characterization of the oligosaccharide chains of human alpha1-microglobulin from urine and amniotic fluid.
Q36559850Structure and function of glycosphingolipids and sphingolipids: recollections and future trends
Q38361429Structure-function analysis of P-selectin-sialyl LewisX binding interactions. Mutagenic alteration of ligand binding specificity
Q41048755Studies on the interaction between hyaluronan and a rat colon cancer cell line
Q38331154Sulfatide from the pig jejunum brush border epithelial cell surface is involved in binding of Escherichia coli enterotoxin b.
Q51754277Sulfochitosan inhibits P-selectin-mediated HL-60 leukocyte adhesion under flow conditions.
Q38339301Sulfomucins in the human body
Q36297281Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting
Q22010048Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin
Q41091026Supramolecular assemblies of a conjugate of nucleobase, amino acids, and saccharide act as agonists for proliferation of embryonic stem cells and development of zygotes
Q43569169Synthesis and biological evaluation of a sialyl Lewis X mimic with significantly improved E-selectin inhibition
Q77576551Synthesis of alpha,alpha-, alpha,Beta-, and Beta,Beta-(dimaltoside)s of ethane-1,2-diol, propane-1,3-diol, and butane-1,4-diol: a proposal for an initial adhesion mode
Q47786094Synthesis of sialyl LeX ganglioside analogues modified at C-6 of the galactose residue to elucidate the mechanism of selection recognition
Q30960455Synthetic potential of molluscan sulfatases for the library synthesis of regioselectively O-sulfonated D-galacto-sugars
Q38312410System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution
Q37483158Systematic analysis of in vitro cell rolling using a multi-well plate microfluidic system
Q38335034TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands
Q36375611Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration
Q36947594Targeting Underglycosylated MUC1 for the Selective Capture of Highly Metastatic Breast Cancer Cells Under Flow
Q51237398Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.
Q52166012Temporal and spatial regulation of expression of two galectins during kidney development of the chicken.
Q58808010The Binding of T Cell-expressed P-selectin Glycoprotein Ligand-1 to E- and P-selectin Is Differentially Regulated
Q30432073The Effects of Load on E-Selectin Bond Rupture and Bond Formation
Q59265017The Glycosylation of Rat Intestinal Muc2 Mucin Varies between Rat Strains and the Small and Large Intestine
Q26750877The Sweet Side of Immune Evasion: Role of Glycans in the Mechanisms of Cancer Progression
Q40842347The adhesive properties of recombinant soluble L-selectin are modulated by its glycosylation
Q34709412The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity
Q40788843The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep.
Q35025910The effect of the selectin binding polysaccharide fucoidin on eosinophil recruitment in vivo
Q42082826The effects of heparin and related molecules on vascular permeability and neutrophil accumulation in rabbit skin.
Q35172546The emerging importance of α-L-fucose in human breast cancer: a review.
Q38367124The expanding field of platelet-bacterial interconnections
Q81077941The expression of E-selectin and chemokines in the cultured human lymphatic endothelium with lipopolysaccharides
Q33897219The glycosynapse
Q24528214The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils
Q71118216The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan
Q33654873The polysaccharide fucoidin inhibits the antibiotic-induced inflammatory cascade in experimental pneumococcal meningitis.
Q85028566The potential role of RTN3 in monocyte recruitment and atherosclerosis
Q41111887The role of cell adhesion molecules and proteases in tumor invasion and metastasis
Q47372818The role of dimension in multivalent binding events: structure-activity relationship of dendritic polyglycerol sulfate binding to L-selectin in correlation with size and surface charge density.
Q46815106The role of mucin-educated platelet activation in tumor invasiveness: An unfolding concern in the realm of cancer biology
Q37869349The thrombotic potential of oral pathogens
Q33786780The versican C-type lectin domain recognizes the adhesion protein tenascin-R.
Q28365403Therapeutic potential of a novel synthetic selectin blocker, OJ-R9188, in allergic dermatitis
Q38290387Tissue Targeting of Multivalent LeX-terminated N-Linked Oligosaccharides in Mice
Q31652037Transendothelial migration of monocytes in rat aorta: distribution of F-actin, alpha-catnin, LFA-1, and PECAM-1.
Q40796882Transfection of the c-erbB2/neu gene upregulates the expression of sialyl Lewis X, alpha1,3-fucosyltransferase VII, and metastatic potential in a human hepatocarcinoma cell line
Q35554103Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-Cancer Vaccines
Q34048052Tumour-associated carbohydrate antigens in breast cancer
Q41110602Two selectins converge on sulphate. Leukocyte adhesion
Q34295441Tyrosine sulfation of P-selectin glycoprotein ligand-1 is required for high affinity binding to P-selectin
Q57183105Ultrasmall superparamagnetic iron oxide nanoparticles coated with fucoidan for molecular MRI of intraluminal thrombus
Q35590174Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface
Q36091832Vesicle size and stability of biomimetic liposomes from 3'-sulfo-Lewis a (SuLea) containing glycolipids
Q70920510[Protein-carbohydrate recognition. Foundation and medical application with illustrations of tumor lectin studies]
Q71553277[Structural and functional aspects of oligosaccharides in human milk]
Q38317234alpha(1,2)-fucosylation prevents sialyl Lewis x expression and E-selectin-mediated adhesion of fucosyltransferase VII-transfected cells

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