Modulation of Splicing by Single-Stranded Silencing RNAs

scientific article published on 10 March 2015

Modulation of Splicing by Single-Stranded Silencing RNAs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/NAT.2014.0527
P932PMC publication ID4440996
P698PubMed publication ID25757055

P2093author name stringJing Liu
David R Corey
Thazha P Prakash
Jiaxin Hu
Jessica A Hicks
P2860cites workAntisense-mediated exon skipping: taking advantage of a trick from Mother Nature to treat rare genetic diseasesQ38184276
Import routes and nuclear functions of Argonaute and other small RNA-silencing proteins.Q38240731
Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defectsQ38247135
The influence of Argonaute proteins on alternative RNA splicingQ38254276
Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscleQ40177871
Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.Q42152387
Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animalsQ44199808
Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 studyQ45033314
Argonaute proteins couple chromatin silencing to alternative splicing.Q45345567
Specific and potent RNAi in the nucleus of human cellsQ45345569
Control of alternative splicing through siRNA-mediated transcriptional gene silencing.Q45960034
Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy.Q52547202
Local dystrophin restoration with antisense oligonucleotide PRO051Q80412961
Single-stranded siRNAs activate RNAi in animalsQ84913472
MicroRNA-373 induces expression of genes with complementary promoter sequencesQ24652547
A chemical view of oligonucleotides for exon skipping and related drug applicationsQ26863684
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplexQ27653175
Argonaute2 is the catalytic engine of mammalian RNAiQ27860545
RNAi factors are present and active in human cell nucleiQ28111715
Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAsQ33632395
Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAsQ33939348
Long non-coding RNA targeting and transcriptional de-repressionQ34326761
Promoter RNA links transcriptional regulation of inflammatory pathway genesQ34368214
RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyondQ34385616
The varied roles of nuclear argonaute-small RNA complexes and avenues for therapyQ34440319
The status of exon skipping as a therapeutic approach to duchenne muscular dystrophyQ34473336
Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cellsQ34480743
Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promotersQ35120827
Exon-skipping therapy: a roadblock, detour, or bump in the road?Q35731229
Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicingQ35740521
Argonaute and the nuclear RNAs: new pathways for RNA-mediated control of gene expressionQ35867143
Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.Q36239309
MicroRNA-directed transcriptional gene silencing in mammalian cellsQ36945167
ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategyQ37271206
Transcriptional silencing by single-stranded RNAs targeting a noncoding RNA that overlaps a gene promoterQ37541625
Chromatin remodeling by the small RNA machinery in mammalian cellsQ37591539
Intracellular localization and routing of miRNA and RNAi pathway componentsQ37971099
Targeting mRNA splicing as a potential treatment for Duchenne muscular dystrophyQ38030657
P4510describes a project that usesImageJQ1659584
P433issue3
P304page(s)113-120
P577publication date2015-03-10
P1433published inNucleic Acid TherapeuticsQ19297428
P1476titleModulation of Splicing by Single-Stranded Silencing RNAs
P478volume25

Reverse relations

cites work (P2860)
Q28080201MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions
Q90110761MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing
Q38289648Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs
Q26776412Regulation of mammalian transcription and splicing by Nuclear RNAi
Q37015869Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

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