Functional deficiency in IL-7 caused by an N-ethyl-N-nitrosourea-induced point mutation

scientific article published on 18 December 2006

Functional deficiency in IL-7 caused by an N-ethyl-N-nitrosourea-induced point mutation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1534/GENETICS.106.066043
P932PMC publication ID1800635
P698PubMed publication ID17179092
P5875ResearchGate publication ID6621329

P50authorHerbert C. MorseQ37375260
P2093author name stringHongsheng Wang
Jianxun Feng
P2860cites workDefective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiencyQ22008480
Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytesQ24628849
Interleukin 7 is produced by murine and human keratinocytesQ24680412
Cre recombinase: the universal reagent for genome tailoringQ28145361
Marginal-zone B cellsQ28201000
Stimulation of B-cell progenitors by cloned murine interleukin-7Q28294062
A gene-driven approach to the identification of ENU mutants in the mouseQ31039073
Sequence-based analysis of mutagenized miceQ33961944
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locusQ35064395
The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenanceQ36133008
IL-7: a key regulator of B lymphopoiesisQ36319746
Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.Q36361984
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient miceQ36364066
Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell populationQ36367974
Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- miceQ36369614
B-1 B cell developmentQ36571904
Expression and function of the interleukin 7 receptor in murine lymphocytesQ36574038
Evidence of marginal-zone B cell-positive selection in spleenQ40372076
A VH12 transgenic mouse exhibits defects in pre-B cell development and is unable to make IgM+ B cellsQ40790800
Constitutive expression of interleukin-7 mRNA and production of IL-7 by a cloned murine thymic stromal cell lineQ41723545
B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursorsQ41820546
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.Q42064178
Elucidation of a downstream boundary of the 3' IgH regulatory regionQ43169305
Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigensQ44296985
Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.Q52205977
Autocrine expression of interleukin-7 rescues lymphoid expansion in interleukin-7-deficient mice.Q52529328
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell developmentQ57339934
A critical role of λ5 protein in B cell developmentQ57339983
A class switch control region at the 3′ end of the immunoglobulin heavy chain locusQ59886033
Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expressionQ73407033
Keeping track of pro-B cells: a new model for the effects of IL-7 during B cell developmentQ80565253
Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient miceQ80885866
Origins of peripheral B cells in IL-7 receptor-deficient miceQ81535109
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)545-551
P577publication date2006-12-18
P1433published inGeneticsQ3100575
P1476titleFunctional deficiency in IL-7 caused by an N-ethyl-N-nitrosourea-induced point mutation
P478volume175

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cites work (P2860)
Q36927177A new mouse mutant for the LDL receptor identified using ENU mutagenesis
Q33684326Dissecting mammalian immunity through mutation.
Q50537421Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.
Q41575103Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors.

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