Plasticity of purine release during cerebral ischemia: clinical implications?

scientific article published on October 2003

Plasticity of purine release during cerebral ischemia: clinical implications? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1582-4934.2003.TB00239.X
P932PMC publication ID6740112
P698PubMed publication ID14754505

P50authorNicholas DaleQ42182994
Bruno G FrenguelliQ42530713
Enrique LlaudetQ46487087
P2093author name stringT Pearson
Lori-An V Etherington
Karen Damian
Anne E Gadalla
Ailsa J Currie
P2860cites workInosine binds to A3 adenosine receptors and stimulates mast cell degranulationQ24561372
Ischemic cell death in brain neuronsQ28145434
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptorsQ28209239
Adenosine: does it have a neuroprotective role after all?Q73019376
Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damageQ73149811
Increase in plasma adenosine during brain ischemia in man: a study during transient ischemic attacks, and strokeQ73515528
Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal sliceQ73948192
Volume-regulated anion channels do not contribute extracellular adenosine during the hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampusQ74261550
Delayed production of adenosine underlies temporal modulation of swimming in frog embryoQ74810964
Pharmacological characterization of swelling-induced D-[3H]aspartate release from primary astrocyte culturesQ77060769
Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain sliceQ69693553
Neuronal damage following repeated brief ischemia in the gerbilQ69961646
Effect of adenosine versus adenine nucleotides on evoked potentials in a rat hippocampal slice preparationQ70885143
The metabolism of purine and pyrimidine nucleotides in rat cortex during insulin-induced hypoglycemia and recoveryQ71482376
Inhibition of NMDA receptor-mediated currents in isolated rat hippocampal neurones by adenosine A1 receptor activationQ72030733
Oxypurinol-enhanced postischemic recovery of the rat brain involves preservation of adenine nucleotidesQ72169591
Adenosine, adenosine receptors and myocardial protection: an updated overviewQ28216213
Receptors for purines and pyrimidinesQ28283941
A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in miceQ28594915
Aggravated brain damage after hypoxic ischemia in immature adenosine A2A knockout miceQ31134464
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivoQ31920069
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cellsQ32065053
Adenosine in sleep and wakefulnessQ33645408
Adenosine and suppression of seizuresQ33748604
Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus.Q33797583
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptorQ33931315
Fine-tuning neuromodulation by adenosineQ34023335
Extracellular metabolism of ATP and other nucleotidesQ34101805
Functions of neuronal adenosine receptorsQ34101843
D-Ribose as a supplement for cardiac energy metabolismQ34126034
Adenosine in the treatment of stroke: yes, maybe, or absolutely not?Q34204326
The role and regulation of adenosine in the central nervous systemQ34205330
Synaptic P2X receptorsQ34278097
Adenosine A(2A) receptor antagonist treatment of Parkinson's diseaseQ34536127
Ischemic tolerance.Q35002089
Adenosine receptors in the nervous system: pathophysiological implications.Q35063214
Behavioral characterization of mice lacking the A3 adenosine receptor: sensitivity to hypoxic neurodegenerationQ35133003
Adenosine in the spinal cord and periphery: release and regulation of painQ35145661
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics.Q35172268
Cerebral metabolism in ischaemia: neurochemical basis for therapyQ39845629
Adenosine: a potential mediator of seizure arrest and postictal refractorinessQ41102217
Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemiaQ41356403
Neuroprotective effects of adenosine in cerebral ischemia: window of opportunityQ41377116
Increases in cerebral cortical perfusate adenosine and inosine concentrations during hypoxia and ischemiaQ41467347
Role of adenosine as a modulator of synaptic activity in the central nervous systemQ41478113
Preferential activation of excitatory adenosine receptors at rat hippocampal and neuromuscular synapses by adenosine formed from released adenine nucleotidesQ42011931
Presence of Kynurenic Acid in the Mammalian BrainQ42214297
Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortexQ42440429
Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditionsQ42526953
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injuryQ43541042
A depletable pool of adenosine in area CA1 of the rat hippocampus.Q43551107
Right thing at a wrong time? Adenosine A3 receptors and cerebroprotection in strokeQ43681322
The effect of allopurinol on focal cerebral ischaemia: an experimental study in rabbitsQ43695564
Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicityQ43860882
Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brainQ43883952
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibitionQ44014265
Does caffeine intake protect from Alzheimer's disease?Q44051650
ATP-induced in vivo neurotoxicity in the rat striatum via P2 receptorsQ44157082
Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.Q44161143
Resetting intrinsic purinergic modulation of neural activity: an associative mechanism?Q44228555
Neuroprotective effect of GMP in hippocampal slices submitted to an in vitro model of ischemia.Q44241098
Activity-dependent release of adenosine contributes to short-term depression at CA3-CA1 synapses in rat hippocampus.Q44274606
Pharmacology of ischemia-induced glutamate efflux from rat cerebral cortex in vitro.Q44306234
Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the RatQ44407127
Convergent control of synaptic GABA release from rat dorsal horn neurones by adenosine and GABA autoreceptorsQ44502614
Up-regulation of P2X2, P2X4 receptor and ischemic cell death: prevention by P2 antagonistsQ44505580
Mononucleotide metabolism in the rat brain after transient ischemiaQ44520476
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged ratsQ44540594
Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD.Q44545760
High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices.Q44570072
AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.Q44792363
Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature ratsQ45003157
Increased vulnerability of the mildly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injuryQ45030387
Release of adenosine by activation of NMDA receptors in the hippocampus.Q45964014
Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat.Q47949477
Changes of adenosine and its A(1) receptor in hypoxic preconditioningQ48108532
Adenosine: a sensitive indicator of cerebral ischemia during carotid endarterectomyQ48139197
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampusQ48236923
Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditionsQ48251269
Involvement of P2 purinoceptors and the nitric oxide pathway in [3H]purine outflow evoked by short-term hypoxia and hypoglycemia in rat hippocampal slicesQ48253567
Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemiaQ48259789
Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampusQ48273810
Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blockerQ48290011
Adenosine 5'-triphosphate release from the normoxic and hypoxic in vivo rat cerebral cortexQ48320744
Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brainQ48419290
Increased ATP production during long-term brain ischemia in rats in the presence of propentofyllineQ48428020
Adenosine depletion alters postictal hypoxic cerebral vasodilation in the newborn pig.Q48457410
Flow thresholds for extracellular purine catabolite elevation in cat focal ischemiaQ48482046
Tamoxifen, a chloride channel blocker, reduces glutamate and aspartate release from the ischemic cerebral cortexQ48508648
Purine nucleotide metabolism in the cat brain after one hour of complete ischemiaQ48536228
Source of extracellular brain adenosine during hypoxia in fetal sheepQ48540123
Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humansQ48583746
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampusQ48597401
A postsynaptic interaction between dopamine D1 and NMDA receptors promotes presynaptic inhibition in the rat nucleus accumbens via adenosine release.Q48658263
The effects of metabolic stress on glutamate receptor-mediated depolarizations in the in vitro rat hippocampal sliceQ48665993
Cerebral energy metabolism during severe ischemia of varying duration and following reperfusionQ48909888
Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampusQ48968995
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.Q48982620
Different response of adenine nucleotide synthesis de novo in kidney and brain during aerobic recovery from anoxia and ischemiaQ51123633
Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient IschemiaQ57982925
P433issue4
P921main subjectcerebral infarctionQ1209150
P304page(s)362-375
P577publication date2003-10-01
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titlePlasticity of purine release during cerebral ischemia: clinical implications?
P478volume7

Reverse relations

cites work (P2860)
Q28573737Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats
Q48412364Adenosine released by astrocytes contributes to hypoxia-induced modulation of synaptic transmission.
Q47105207Blood purine measurements as a rapid real-time indicator of reversible brain ischaemia
Q42533509Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum.
Q35210040Differential contributions of adenosine to hypoxia-evoked depressions of three neuronal pathways in isolated spinal cord of neonatal rats.
Q48456190Endogenous activation of adenosine A(1) receptors accelerates ischemic suppression of spontaneous electrocortical activity.
Q36477852Enteric Glial Cells: A New Frontier in Neurogastroenterology and Clinical Target for Inflammatory Bowel Diseases
Q28576289Expression of ecto-nucleoside triphosphate diphosphohydrolase1-3 (NTPDase1-3) by cortical astrocytes after exposure to pro-inflammatory factors in vitro
Q28578172HIF-1 alpha is an essential effector for purine nucleoside-mediated neuroprotection against hypoxia in PC12 cells and primary cerebellar granule neurons
Q36356591Hypoxia-induced changes in neuronal network properties.
Q44338161Hypoxia-ischemia alters nucleotide and nucleoside catabolism and Na+,K+-ATPase activity in the cerebral cortex of newborn rats.
Q37268106Ischemic tolerance as an active and intrinsic neuroprotective mechanism
Q37957734Measurement of purine release with microelectrode biosensors
Q48308531Neuroinflammation after neonatal hypoxia-ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult
Q38110513Neuromodulation: purinergic signaling in respiratory control
Q46937494Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain
Q37700194Release of adenosine and ATP during ischemia and epilepsy
Q37230672Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro
Q41964528Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus
Q48142175The Purine Salvage Pathway and the Restoration of Cerebral ATP: Implications for Brain Slice Physiology and Brain Injury.
Q93186026The Purinome and the preBötzinger Complex - A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response
Q58693534The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures
Q36131077The role of ATP and adenosine in the brain under normoxic and ischemic conditions