A fluorescent approach for identifying P2X1 ligands

scientific article published on 28 May 2015

A fluorescent approach for identifying P2X1 ligands is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEUROPHARM.2015.05.016
P932PMC publication ID4728187
P698PubMed publication ID26026951
P5875ResearchGate publication ID277337691

P50authorMarc-David RueppQ55143880
Richard W FarndaleQ61665886
Iwan J P de EschQ89095911
P2093author name stringAndrew J Thompson
James A Brozik
Ruth D Murrell-Lagnado
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Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytesQ39969794
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Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loopQ40725974
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Design, synthesis, and structure-activity relationships of highly potent 5-HT₃ receptor ligandsQ41738282
Conformational flexibility of the agonist binding jaw of the human P2X3 receptor is a prerequisite for channel openingQ41892145
Platelet Ca(2+) responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca(2+) storesQ42326717
NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptorsQ43718770
Carbamazepine derivatives with P2X4 receptor-blocking activity.Q43752016
Pharmacological characterization of P2X1 and P2X3 purinergic receptors in bovine chondrocytesQ44844969
Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladderQ46298821
FlexStation examination of 5-HT3 receptor function using Ca2+ - and membrane potential-sensitive dyes: advantages and potential problems.Q46614630
Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization.Q47907840
N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.Q48332530
Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cellsQ74320313
Critical review of the role of HTS in drug discoveryQ83039041
P4510describes a project that usesImageJQ1659584
P1104number of pages9
P304page(s)13-21
P577publication date2015-05-28
P1433published inNeuropharmacologyQ15332439
P1476titleA fluorescent approach for identifying P2X1 ligands
P478volume98

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Q33843023Unraveling the Thousand Word Picture: An Introduction to Super-Resolution Data Analysiscites workP2860

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