Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein

scientific article published on 29 November 2011

Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.312736
P932PMC publication ID3256919
P698PubMed publication ID22128191

P2093author name stringJonah R Chan
Bruce Appel
Bruce D Carter
Allison S Limpert
Sung Ok Yoon
Chhavy Tep
Laura I Opincariu
Mi Lyang Kim
P2860cites workThe cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Q24534460
Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexesQ24647211
Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.Q27919621
Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotypeQ28118345
Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouseQ28201973
Axonal neuregulin-1 regulates myelin sheath thicknessQ28504655
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous systemQ28505213
Role of the PAR-3-KIF3 complex in the establishment of neuronal polarityQ28568399
Neuregulin-1 type III determines the ensheathment fate of axonsQ28585039
Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migrationQ28590412
Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelinationQ28756758
The PAR proteins: fundamental players in animal cell polarizationQ30434403
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.Q30436000
CNS-derived glia ensheath peripheral nerves and mediate motor root developmentQ30486558
Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimersQ33607417
Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPasesQ34515430
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytesQ41950217
Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.Q42480871
Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia.Q44678858
BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons.Q46064931
Anterograde transport and secretion of brain-derived neurotrophic factor along sensory axons promote Schwann cell myelination.Q46274835
p75 is important for axon growth and schwann cell migration during development.Q46547849
Neuromuscular synapses can form in vivo by incorporation of initially aneural postsynaptic specializationsQ46703175
The polarity protein Par-3 directly interacts with p75NTR to regulate myelinationQ46887211
Neural cell fate analysis in zebrafish using olig2 BAC transgenicsQ48087863
Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.Q53572324
Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires PI 3-kinase activityQ73870801
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectSchwann cellQ465621
myelinationQ14876135
P304page(s)1600-1608
P577publication date2011-11-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleBrain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein
P478volume287

Reverse relations

cites work (P2860)
Q30662472Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A.
Q41215173Effects of Angelica Extract on Schwann Cell Proliferation and Expressions of Related Proteins.
Q54358341Electrically induced brain-derived neurotrophic factor release from Schwann cells.
Q50051093Establishment of a myelinating co-culture system with a motor neuron-like cell line NSC-34 and an adult rat Schwann cell line IFRS1.
Q58712573From Neural Crest Development to Cancer and Vice Versa: How p75 and (Pro)neurotrophins Could Act on Cell Migration and Invasion?
Q34670337Gene expression profiling studies in regenerating nerves in a mouse model for CMT1X: uninjured Cx32-knockout peripheral nerves display expression profile of injured wild type nerves
Q58730941Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis
Q89797903Loss-of-function of EBP50 is a new cause of hereditary peripheral neuropathy: EBP50 functions in peripheral nerve system
Q30360890Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway.
Q38364430Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system
Q90751595Necl-4/Cadm4 recruits Par-3 to the Schwann cell adaxonal membrane
Q38225912Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases
Q27335688Pard3 regulates contact between neural crest cells and the timing of Schwann cell differentiation but is not essential for neural crest migration or myelination
Q35101108Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent
Q36530065Polarization and myelination in myelinating glia
Q38455974Rac1 controls Schwann cell myelination through cAMP and NF2/merlin
Q28085669Role of Schwann cells in the regeneration of penile and peripheral nerves
Q91848778Schwann cell interactions during the development of the peripheral nervous system
Q35876798The Polarity Protein Pals1 Regulates Radial Sorting of Axons
Q34176631Using the neurofibromatosis tumor predisposition syndromes to understand normal nervous system development
Q37391606miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins
Q34467645p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1.

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