Molecular medicine for the brain: silencing of disease genes with RNA interference

scientific article published on March 2004

Molecular medicine for the brain: silencing of disease genes with RNA interference is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1474-4422(04)00678-7
P698PubMed publication ID14980529

P2093author name stringBeverly L Davidson
Henry L Paulson
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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
RNA interferenceQ28131798
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2Q28181376
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologueQ28506834
Inactivation of the mouse Huntington's disease gene homolog HdhQ28509662
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in miceQ28594828
Expression profiling reveals off-target gene regulation by RNAiQ29615965
Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectorsQ34028579
Toxic proteins in neurodegenerative diseaseQ34133493
siRNA-mediated gene silencing in vitro and in vivo.Q34150604
RNAi functions in cultured mammalian neuronsQ34154748
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosisQ34224830
In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteinsQ34344453
Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interferenceQ34520619
Genetics of primary dystoniaQ34795185
Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.Q35111738
The specifics of small interfering RNA specificityQ35142626
Genomewide view of gene silencing by small interfering RNAsQ35142839
Allele-specific silencing of dominant disease genesQ35163317
Approaches for the sequence-specific knockdown of mRNA.Q35597089
Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant allelesQ37069801
Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approachQ40870377
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral deliveryQ43685007
BACE1 Suppression by RNA Interference in Primary Cortical NeuronsQ44643912
Local gene knockdown in the brain using viral-mediated RNA interference.Q44666833
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiencyQ45857796
Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinAQ73470858
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectRNA interferenceQ201993
gene silencingQ1431332
P304page(s)145-149
P577publication date2004-03-01
P1433published inLancet NeurologyQ15755067
P1476titleMolecular medicine for the brain: silencing of disease genes with RNA interference
P478volume3

Reverse relations

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