Systemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy

scientific article published on August 2014

Systemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/STEM.1727
P932PMC publication ID4454401
P698PubMed publication ID24801379
P5875ResearchGate publication ID262077063

P2093author name stringBakhos A Tannous
Jian Teng
Christian E Badr
Seyedali Hejazi
P2860cites workDNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistanceQ26825975
Transmigration of neural stem cells across the blood brain barrier induced by glioma cellsQ27329613
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trialQ29547224
Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectorsQ33779347
Functional drug screening assay reveals potential glioma therapeuticsQ33780121
Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage?Q34078735
Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platformQ34691557
Novel therapeutic applications of cardiac glycosidesQ34864765
Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathwayQ35419466
Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP.Q35665706
Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.Q35696355
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomasQ35827956
Emerging insights into the molecular and cellular basis of glioblastomaQ35914897
Targeting cancer cells with the natural compound obtusaquinone.Q36953575
Triple bioluminescence imaging for in vivo monitoring of cellular processes.Q36968192
Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivoQ37217394
A secreted luciferase for ex vivo monitoring of in vivo processesQ37235465
The TRAIL apoptotic pathway in cancer onset, progression and therapyQ37278043
Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.Q37344283
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studiesQ37396577
TRAIL on trial: preclinical advances in cancer therapyQ37433463
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsQ37447217
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emergeQ37729676
Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta stoneQ37879267
Neural stem cell transplantation in central nervous system disorders: from cell replacement to neuroprotectionQ38006628
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Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastomaQ39374075
Microvesicle-associated AAV vector as a novel gene delivery systemQ39400043
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma modelsQ39630653
Irradiation Enhances the Tumor Tropism and Therapeutic Potential of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Glioma TherapyQ39644411
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivoQ41723484
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regressionQ42835214
Absorption and metabolism of lanatoside C. II. Fate after oral administrationQ44128474
Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivoQ44611172
Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.Q45890216
In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke modelsQ48876895
Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studiesQ49069202
P433issue8
P921main subjectglioblastomaQ282142
neural stem cellQ2944097
P304page(s)2021-2032
P577publication date2014-08-01
P1433published inStem CellsQ15724411
P1476titleSystemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy
P478volume32

Reverse relations

cites work (P2860)
Q33902853Elimination of undifferentiated human embryonic stem cells by cardiac glycosides
Q91604362Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs
Q99207673Feasibility of intracerebrally administering multiple doses of genetically modified neural stem cells to locally produce chemotherapy in glioma patients
Q36919260Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase
Q26799013Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities
Q26783167Neural Stem Cell Carriers for the Treatment of Glioblastoma Multiforme
Q38626364New therapeutic strategies regarding endovascular treatment of glioblastoma, the role of the blood-brain barrier and new ways to bypass it.
Q91765663Olfactory Ensheathing Cells: A Trojan Horse for Glioma Gene Therapy
Q47988508Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
Q37109638The homing and inhibiting effects of hNSCs-BMP4 on human glioma stem cells
Q36636067Therapeutic potential of targeting microRNA-10b in established intracranial glioblastoma: first steps toward the clinic.

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